rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9P7H3 | 282 | PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyce... | 272 | 1e-131 | 381 | 67 | 83 | GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007007; P:inner mitochondrial membrane organization; ISS:PomBase.::GO:0000001; P:mitochondrion inheritance; ISS:PomBase.::GO:0006457; P:protein folding; ISS:PomBase. | 2 | P40961 | 287 | PHB1_YEAST Prohibitin-1 OS=Saccharomyces cere... | 253 | 9e-129 | 374 | 70 | 84 | GO:0005743; C:mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007007; P:inner mitochondrial membrane organization; IMP:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0070584; P:mitochondrion morphogenesis; IMP:SGD.::GO:0045861; P:negative regulation of proteolysis; IPI:SGD.::GO:0006457; P:protein folding; IPI:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 3 | Q54GI9 | 271 | PHB1_DICDI Prohibitin-1, mitochondrial OS=Dic... | 268 | 7e-112 | 330 | 58 | 78 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 4 | P84173 | 272 | PHB_CHICK Prohibitin OS=Gallus gallus (Chicke... | 257 | 1e-107 | 320 | 59 | 78 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 5 | P67779 | 272 | PHB_RAT Prohibitin OS=Rattus norvegicus (Rat)... | 257 | 3e-107 | 318 | 58 | 78 | GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0001552; P:ovarian follicle atresia; IEP:RGD.::GO:0001541; P:ovarian follicle development; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0006950; P:response to stress; IEP:RGD. | 6 | P67778 | 272 | PHB_MOUSE Prohibitin OS=Mus musculus (Mouse).... | 257 | 3e-107 | 318 | 58 | 78 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0071897; P:DNA biosynthetic process; IMP:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 7 | P35232 | 272 | PHB_HUMAN Prohibitin OS=Homo sapiens (Human).... | 257 | 1e-106 | 317 | 58 | 78 | GO:0005887; C:integral to plasma membrane; IDA:HGNC.::GO:0005743; C:mitochondrial inner membrane; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0071354; P:cellular response to interleukin-6; IDA:BHF-UCL.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016575; P:histone deacetylation; IDA:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.::GO:2000323; P:negative regulation of glucocorticoid receptor signaling pathway; IDA:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB. | 8 | Q3T165 | 272 | PHB_BOVIN Prohibitin OS=Bos taurus (Bovine). ... | 257 | 1e-106 | 317 | 58 | 78 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 9 | P24156 | 276 | L2CC_DROME Protein l(2)37Cc OS=Drosophila mel... | 261 | 2e-103 | 309 | 57 | 75 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 10 | Q9BKU4 | 275 | PHB1_CAEEL Mitochondrial prohibitin complex p... | 250 | 5e-99 | 298 | 58 | 77 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030421; P:defecation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0070584; P:mitochondrion morphogenesis; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0002082; P:regulation of oxidative phosphorylation; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 11 | Q54Q31 | 293 | PHB2_DICDI Prohibitin-2 OS=Dictyostelium disc... | 246 | 4e-96 | 291 | 58 | 78 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 12 | P50085 | 310 | PHB2_YEAST Prohibitin-2 OS=Saccharomyces cere... | 234 | 9e-93 | 283 | 57 | 79 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0045861; P:negative regulation of proteolysis; IPI:SGD.::GO:0006457; P:protein folding; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 13 | O94550 | 288 | PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyce... | 241 | 3e-91 | 278 | 56 | 74 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0006457; P:protein folding; ISS:PomBase. | 14 | O35129 | 299 | PHB2_MOUSE Prohibitin-2 OS=Mus musculus (Mous... | 264 | 3e-86 | 266 | 50 | 73 | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0060744; P:mammary gland branching involved in thelarche; IMP:MGI.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:MGI.::GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q99623 | 299 | PHB2_HUMAN Prohibitin-2 OS=Homo sapiens (Huma... | 264 | 3e-86 | 266 | 50 | 73 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q5XIH7 | 299 | PHB2_RAT Prohibitin-2 OS=Rattus norvegicus (R... | 264 | 4e-86 | 266 | 50 | 73 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q5RB19 | 299 | PHB2_PONAB Prohibitin-2 OS=Pongo abelii (Suma... | 261 | 4e-86 | 265 | 51 | 74 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q2HJ97 | 299 | PHB2_BOVIN Prohibitin-2 OS=Bos taurus (Bovine... | 264 | 3e-85 | 263 | 50 | 73 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | A9UMS3 | 301 | PHB2_XENTR Prohibitin-2 OS=Xenopus tropicalis... | 264 | 1e-84 | 262 | 50 | 73 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | P50093 | 294 | PHB2_CAEEL Mitochondrial prohibitin complex p... | 246 | 2e-83 | 259 | 50 | 74 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030421; P:defecation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0070584; P:mitochondrion morphogenesis; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0002082; P:regulation of oxidative phosphorylation; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 21 | Q5ZMN3 | 301 | PHB2_CHICK Prohibitin-2 OS=Gallus gallus (Chi... | 250 | 1e-81 | 254 | 50 | 74 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | P86220 | 87 | PHB_MESAU Prohibitin OS=Mesocricetus auratus ... | 114 | 7e-16 | 74.7 | 44 | 53 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 23 | O28852 | 249 | Y1420_ARCFU Uncharacterized protein AF_1420 O... | 198 | 0.0003 | 45.1 | 24 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 24 | P0AA56 | 305 | QMCA_SHIFL Protein QmcA OS=Shigella flexneri.... | 247 | 0.002 | 42.7 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 25 | P0AA53 | 305 | QMCA_ECOLI Protein QmcA OS=Escherichia coli (... | 247 | 0.002 | 42.7 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 26 | P0AA54 | 305 | QMCA_ECOL6 Protein QmcA OS=Escherichia coli O... | 247 | 0.002 | 42.7 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 27 | P0AA55 | 305 | QMCA_ECO57 Protein QmcA OS=Escherichia coli O... | 247 | 0.002 | 42.7 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 28 | O26788 | 318 | Y692_METTH Uncharacterized protein MTH_692 OS... | 110 | 0.021 | 39.3 | 24 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 29 | P0ABC6 | 334 | HFLC_SHIFL Protein HflC OS=Shigella flexneri.... | 132 | 0.025 | 39.3 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P0ABC3 | 334 | HFLC_ECOLI Modulator of FtsH protease HflC OS... | 132 | 0.025 | 39.3 | 27 | 46 | GO:0071575; C:integral to external side of plasma membrane; IDA:EcoCyc. | | | | | | | | | | GO:0008233; F:peptidase activity; IEA:InterPro. | | | | | | | | | | GO:0048553; P:negative regulation of metalloenzyme activity; IGI:EcoCyc.::GO:0009408; P:response to heat; IEP:EcoCyc. | 31 | P0ABC4 | 334 | HFLC_ECOL6 Protein HflC OS=Escherichia coli O... | 132 | 0.025 | 39.3 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |