rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P61203 | 443 | CSN2_RAT COP9 signalosome complex subunit 2 O... | 454 | 6e-172 | 498 | 56 | 73 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0030182; P:neuron differentiation; IDA:RGD. | 2 | P61202 | 443 | CSN2_MOUSE COP9 signalosome complex subunit 2... | 454 | 6e-172 | 498 | 56 | 73 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0008180; C:signalosome; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 3 | P61201 | 443 | CSN2_HUMAN COP9 signalosome complex subunit 2... | 454 | 6e-172 | 498 | 56 | 73 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0008180; C:signalosome; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:UniProtKB. | | | | | | | | | | GO:0010388; P:cullin deneddylation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB. | 4 | Q6IQT4 | 443 | CSN2_DANRE COP9 signalosome complex subunit 2... | 454 | 3e-171 | 496 | 55 | 73 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 5 | Q6IR75 | 441 | CSN2_XENLA COP9 signalosome complex subunit 2... | 452 | 2e-170 | 494 | 56 | 73 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 6 | Q8W207 | 439 | CSN2_ARATH COP9 signalosome complex subunit 2... | 443 | 2e-164 | 478 | 53 | 73 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0008180; C:signalosome; IPI:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0010388; P:cullin deneddylation; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030163; P:protein catabolic process; TAS:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW. | 7 | Q5B3U7 | 506 | CSN2_EMENI COP9 signalosome complex subunit 2... | 476 | 1e-153 | 454 | 49 | 67 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 8 | Q54HL6 | 449 | CSN2_DICDI COP9 signalosome complex subunit 2... | 428 | 4e-152 | 447 | 50 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IPI:dictyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:dictyBase. | | | | | | | | | | | 9 | Q94899 | 444 | CSN2_DROME COP9 signalosome complex subunit 2... | 439 | 9e-152 | 446 | 51 | 71 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0008231; C:repressor ecdysone receptor complex; IPI:FlyBase.::GO:0008180; C:signalosome; IDA:UniProtKB. | | | | | | | | | | GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:FlyBase.::GO:0035257; F:nuclear hormone receptor binding; IPI:FlyBase.::GO:0042803; F:protein homodimerization activity; IPI:FlyBase.::GO:0003714; F:transcription corepressor activity; IDA:FlyBase. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007275; P:multicellular organismal development; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0050821; P:protein stabilization; IMP:FlyBase. | 10 | Q7SI58 | 490 | CSN2_NEUCR COP9 signalosome complex subunit 2... | 431 | 2e-137 | 411 | 50 | 70 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 11 | Q9HFR0 | 437 | CSN2_SCHPO COP9 signalosome complex subunit 2... | 385 | 2e-129 | 389 | 50 | 71 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0008180; C:signalosome; NAS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0010388; P:cullin deneddylation; NAS:PomBase.::GO:0006974; P:response to DNA damage stimulus; IMP:PomBase. | 12 | O01422 | 495 | CSN2_CAEEL COP9 signalosome complex subunit 2... | 411 | 9e-124 | 377 | 48 | 69 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase. | 13 | A8X379 | 411 | PS11B_CAEBR Probable 26S proteasome regulator... | 376 | 1e-18 | 91.3 | 24 | 46 | GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 14 | Q8BG32 | 422 | PSD11_MOUSE 26S proteasome non-ATPase regulat... | 260 | 3e-18 | 90.5 | 27 | 48 | GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 15 | O00231 | 422 | PSD11_HUMAN 26S proteasome non-ATPase regulat... | 260 | 3e-18 | 90.5 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; TAS:ProtInc. | | | | | | | | | | | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 16 | Q2KI42 | 422 | PSD11_BOVIN 26S proteasome non-ATPase regulat... | 260 | 3e-18 | 90.5 | 27 | 48 | GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 17 | P34481 | 416 | PS11B_CAEEL Probable 26S proteasome regulator... | 379 | 3e-18 | 90.1 | 23 | 46 | GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 18 | Q54UB5 | 413 | PSD11_DICDI 26S proteasome non-ATPase regulat... | 215 | 1e-17 | 88.6 | 26 | 54 | GO:0005838; C:proteasome regulatory particle; ISS:dictyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; ISS:dictyBase. | | | | | | | | | | GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase. | 19 | Q12377 | 434 | RPN6_YEAST 26S proteasome regulatory subunit ... | 283 | 0.00000000000007 | 77 | 26 | 46 | GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; IMP:SGD. | | | | | | | | | | GO:0043248; P:proteasome assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD. | 20 | Q9P7S2 | 421 | RPN6_SCHPO Probable 26S proteasome regulatory... | 256 | 0.0000000000008 | 73.6 | 25 | 48 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase. | 21 | Q20938 | 438 | PS11A_CAEEL Probable 26S proteasome regulator... | 291 | 0.0000008 | 55.1 | 23 | 43 | GO:0005634; C:nucleus; IDA:WormBase.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 22 | Q7RXQ1 | 425 | CSN1_NEUCR COP9 signalosome complex subunit 1... | 245 | 0.0000008 | 55.1 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 23 | Q99LD4 | 471 | CSN1_MOUSE COP9 signalosome complex subunit 1... | 177 | 0.00004 | 49.7 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 24 | Q9VVU5 | 525 | CSN1_DROME COP9 signalosome complex subunit 1... | 177 | 0.00004 | 49.7 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IMP:UniProtKB. | | | | | | | | | | GO:0019781; F:NEDD8 activating enzyme activity; IMP:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0000338; P:protein deneddylation; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IMP:FlyBase. | 25 | P97834 | 471 | CSN1_RAT COP9 signalosome complex subunit 1 O... | 177 | 0.0001 | 48.1 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | | 26 | Q6NRT5 | 487 | CSN1_XENLA COP9 signalosome complex subunit 1... | 177 | 0.0001 | 48.1 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 27 | Q9GS00 | 601 | CSN1_CAEEL COP9 signalosome complex subunit 1... | 105 | 0.0003 | 46.6 | 25 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW. | 28 | Q13098 | 491 | CSN1_HUMAN COP9 signalosome complex subunit 1... | 177 | 0.0005 | 45.8 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IDA:UniProtKB. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc. | | | | | | | | | | GO:0007049; P:cell cycle; TAS:ProtInc.::GO:0010388; P:cullin deneddylation; IDA:UniProtKB.::GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.::GO:0007254; P:JNK cascade; TAS:ProtInc. | 29 | B5DGH9 | 445 | EIF3E_SALSA Eukaryotic translation initiation... | 108 | 0.031 | 40.4 | 26 | 52 | GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q3B8M3 | 446 | EI3EB_XENLA Eukaryotic translation initiation... | 108 | 0.032 | 40.4 | 26 | 52 | GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | Q6P7L9 | 446 | EIF3E_XENTR Eukaryotic translation initiation... | 108 | 0.038 | 40 | 26 | 52 | GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | |