rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
691 | Q9JJN2 | 3550 | ZFHX4_MOUSE Zinc finger homeobox protein 4 OS... | 79 | 1.7 | 35 | 33 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 692 | Q1KKV3 | 275 | HXCCA_TAKRU Homeobox protein Hox-C12a OS=Taki... | 48 | 1.7 | 34.7 | 31 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 693 | Q05916 | 333 | HME1_CHICK Homeobox protein engrailed-1 OS=Ga... | 48 | 1.7 | 34.7 | 27 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 694 | Q9VK71 | 893 | PDM2B_DROME POU domain protein 2, isoform B O... | 43 | 1.7 | 35 | 35 | 58 | GO:0005634; C:nucleus; IMP:UniProtKB. | | | | | | | | | | GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0007398; P:ectoderm development; IMP:UniProtKB.::GO:0014019; P:neuroblast development; IMP:FlyBase. | 695 | Q91907 | 340 | GBX2_XENLA Homeobox protein GBX-2 OS=Xenopus ... | 64 | 1.7 | 34.7 | 28 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 696 | P31259 | 309 | HXB1_CHICK Homeobox protein Hox-B1 OS=Gallus ... | 64 | 1.7 | 34.7 | 30 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 697 | Q90470 | 276 | HXDBA_DANRE Homeobox protein Hox-D11a OS=Dani... | 57 | 1.7 | 34.7 | 33 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 698 | Q5TM83 | 305 | NANOG_MUSMM Homeobox protein NANOG OS=Mus mus... | 50 | 1.8 | 34.7 | 30 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 699 | O55144 | 291 | TLX3_MOUSE T-cell leukemia homeobox protein 3... | 93 | 1.8 | 34.3 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 700 | O43711 | 291 | TLX3_HUMAN T-cell leukemia homeobox protein 3... | 57 | 1.8 | 34.7 | 28 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 701 | P78337 | 314 | PITX1_HUMAN Pituitary homeobox 1 OS=Homo sapi... | 62 | 1.8 | 34.7 | 27 | 50 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 702 | Q99NA7 | 315 | PITX1_RAT Pituitary homeobox 1 OS=Rattus norv... | 62 | 1.8 | 34.7 | 27 | 50 | | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:RGD. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 703 | Q91V10 | 363 | VSX1_MOUSE Visual system homeobox 1 OS=Mus mu... | 55 | 1.8 | 34.7 | 29 | 49 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0042551; P:neuron maturation; IGI:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0060040; P:retinal bipolar neuron differentiation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IMP:MGI. | 704 | A6NMT0 | 343 | DBX1_HUMAN Homeobox protein DBX1 OS=Homo sapi... | 74 | 1.8 | 34.7 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 705 | P47237 | 216 | PAX6_CHICK Paired box protein Pax-6 OS=Gallus... | 53 | 1.8 | 34.3 | 36 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 706 | O43812 | 170 | DUX1_HUMAN Double homeobox protein 1 OS=Homo ... | 55 | 1.8 | 33.9 | 33 | 53 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 707 | P34663 | 305 | HM23_CAEEL Homeobox protein ceh-23 OS=Caenorh... | 51 | 1.8 | 34.7 | 33 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 708 | Q91770 | 233 | NOT2_XENLA Homeobox protein not2 OS=Xenopus l... | 70 | 1.8 | 34.3 | 24 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0014028; P:notochord formation; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 709 | Q9QY61 | 515 | IRX4_MOUSE Iroquois-class homeodomain protein... | 87 | 1.8 | 34.7 | 24 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007507; P:heart development; IMP:MGI. | 710 | P47239 | 503 | PAX7_MOUSE Paired box protein Pax-7 OS=Mus mu... | 49 | 1.9 | 34.7 | 37 | 49 | GO:0005667; C:transcription factor complex; TAS:MGI. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI. | | | | | | | | | | GO:0051216; P:cartilage development; IMP:MGI.::GO:0021904; P:dorsal/ventral neural tube patterning; IDA:MGI.::GO:0048706; P:embryonic skeletal system development; IMP:MGI.::GO:0060415; P:muscle tissue morphogenesis; IGI:MGI.::GO:0048663; P:neuron fate commitment; IGI:MGI.::GO:0014813; P:satellite cell commitment; IMP:MGI.::GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 711 | Q80Z64 | 305 | NANOG_MOUSE Homeobox protein NANOG OS=Mus mus... | 50 | 1.9 | 34.7 | 30 | 54 | GO:0005654; C:nucleoplasm; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0009880; P:embryonic pattern specification; IEP:HGNC.::GO:0008406; P:gonad development; IEP:HGNC.::GO:0001710; P:mesodermal cell fate commitment; IGI:MGI.::GO:0030514; P:negative regulation of BMP signaling pathway; IDA:MGI.::GO:0042664; P:negative regulation of endodermal cell fate specification; TAS:HGNC.::GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.::GO:0045931; P:positive regulation of mitotic cell cycle; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0017145; P:stem cell division; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 712 | P70314 | 315 | PITX1_MOUSE Pituitary homeobox 1 OS=Mus muscu... | 62 | 1.9 | 34.3 | 27 | 50 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0014707; P:branchiomeric skeletal muscle development; IMP:MGI.::GO:0051216; P:cartilage development; IMP:MGI.::GO:0035116; P:embryonic hindlimb morphogenesis; IGI:MGI.::GO:0048625; P:myoblast cell fate commitment; IMP:MGI.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 713 | P21711 | 377 | MIX1_XENLA Homeobox protein Mix.1 OS=Xenopus ... | 60 | 1.9 | 34.7 | 33 | 52 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 714 | O42506 | 283 | HXA9A_TAKRU Homeobox protein Hox-A9a OS=Takif... | 62 | 1.9 | 34.3 | 29 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 715 | P55864 | 422 | PAX6_XENLA Paired box protein Pax-6 OS=Xenopu... | 99 | 1.9 | 34.7 | 30 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 716 | P63015 | 422 | PAX6_MOUSE Paired box protein Pax-6 OS=Mus mu... | 99 | 1.9 | 34.7 | 30 | 44 | GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; TAS:MGI. | | | | | | | | | | GO:0070410; F:co-SMAD binding; IDA:BHF-UCL.::GO:0035035; F:histone acetyltransferase binding; IDA:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IDA:BHF-UCL.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0048708; P:astrocyte differentiation; IMP:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0001709; P:cell fate determination; IMP:MGI.::GO:0021796; P:cerebral cortex regionalization; IMP:MGI.::GO:0021902; P:commitment of neuronal cell to specific neuron type in forebrain; IMP:MGI.::GO:0009950; P:dorsal/ventral axis specification; IMP:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0021797; P:forebrain anterior/posterior pattern specification; IMP:MGI.::GO:0021798; P:forebrain dorsal/ventral pattern formation; IMP:MGI.::GO:0021905; P:forebrain-midbrain boundary formation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0032808; P:lacrimal gland development; IMP:MGI.::GO:0002088; P:lens development in camera-type eye; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0021778; P:oligodendrocyte cell fate specification; IMP:MGI.::GO:0003322; P:pancreatic A cell development; IMP:BHF-UCL.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0033365; P:protein localization to organelle; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0048505; P:regulation of timing of cell differentiation; IMP:MGI.::GO:0021918; P:regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment; IMP:MGI.::GO:0021912; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; IMP:MGI.::GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IMP:MGI.::GO:0007435; P:salivary gland morphogenesis; IMP:MGI.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI.::GO:0007224; P:smoothened signaling pathway; IDA:MGI. | 717 | P26367 | 422 | PAX6_HUMAN Paired box protein Pax-6 OS=Homo s... | 99 | 1.9 | 34.7 | 30 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:BHF-UCL.::GO:0019901; F:protein kinase binding; ISS:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001568; P:blood vessel development; IMP:DFLAT.::GO:0061303; P:cornea development in camera-type eye; IMP:DFLAT.::GO:0042593; P:glucose homeostasis; IMP:DFLAT.::GO:0061072; P:iris morphogenesis; IMP:DFLAT.::GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.::GO:0003322; P:pancreatic A cell development; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0009611; P:response to wounding; IEP:UniProtKB.::GO:0007601; P:visual perception; TAS:ProtInc. | 718 | Q1LZF1 | 422 | PAX6_BOVIN Paired box protein Pax-6 OS=Bos ta... | 99 | 1.9 | 34.7 | 30 | 44 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB. | 719 | P28167 | 3005 | ZFH2_DROME Zinc finger protein 2 OS=Drosophil... | 62 | 1.9 | 35 | 32 | 50 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007399; P:nervous system development; IEP:FlyBase. | 720 | Q00196 | 463 | PO2F2_MOUSE POU domain, class 2, transcriptio... | 66 | 1.9 | 34.7 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0048469; P:cell maturation; IMP:MGI.::GO:0002380; P:immunoglobulin secretion involved in immune response; IMP:MGI.::GO:0002335; P:mature B cell differentiation; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 721 | Q8SW18 | 227 | HD10_ENCCU Homeobox protein HD-10 OS=Encephal... | 58 | 2 | 34.3 | 31 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | |