| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q6U8D7 | 431 | FOXP3_MACFA Forkhead box protein P3 OS=Macaca... | 99 | 0.00000006 | 57.4 | 31 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051525; F:NFAT protein binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; ISS:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; ISS:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; ISS:UniProtKB.::GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042110; P:T cell activation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 212 | Q12778 | 655 | FOXO1_HUMAN Forkhead box protein O1 OS=Homo s... | 109 | 0.00000006 | 57.8 | 35 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 213 | B4KBF6 | 563 | FOXO_DROMO Forkhead box protein O OS=Drosophi... | 112 | 0.00000006 | 57.4 | 38 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 214 | Q61575 | 648 | FOXN1_MOUSE Forkhead box protein N1 OS=Mus mu... | 61 | 0.00000007 | 57.8 | 39 | 62 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IDA:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0033081; P:regulation of T cell differentiation in thymus; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI. | 215 | B4JSC2 | 630 | FOXO_DROGR Forkhead box protein O OS=Drosophi... | 108 | 0.00000007 | 57.4 | 39 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 216 | B4MB78 | 609 | FOXO_DROVI Forkhead box protein O OS=Drosophi... | 112 | 0.00000007 | 57.4 | 38 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 217 | O15353 | 648 | FOXN1_HUMAN Forkhead box protein N1 OS=Homo s... | 61 | 0.00000008 | 57.4 | 39 | 62 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006952; P:defense response; TAS:ProtInc.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IBA:RefGenome.::GO:0030216; P:keratinocyte differentiation; IBA:RefGenome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048538; P:thymus development; IBA:RefGenome. | 218 | Q99JB6 | 429 | FOXP3_MOUSE Forkhead box protein P3 OS=Mus mu... | 99 | 0.0000001 | 56.6 | 31 | 52 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0035035; F:histone acetyltransferase binding; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0051525; F:NFAT protein binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IMP:MGI.::GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0001816; P:cytokine production; IDA:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0002262; P:myeloid cell homeostasis; IMP:MGI.::GO:0002677; P:negative regulation of chronic inflammatory response; IDA:MGI.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IDA:MGI.::GO:0031064; P:negative regulation of histone deacetylation; IBA:RefGenome.::GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IDA:MGI.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; ISS:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; ISS:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; ISS:UniProtKB.::GO:0032714; P:negative regulation of interleukin-5 production; IDA:MGI.::GO:0032715; P:negative regulation of interleukin-6 production; IMP:MGI.::GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IMP:MGI.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; ISS:UniProtKB.::GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IMP:MGI.::GO:0035066; P:positive regulation of histone acetylation; IDA:MGI.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:MGI.::GO:0002851; P:positive regulation of peripheral T cell tolerance induction; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032914; P:positive regulation of transforming growth factor beta1 production; IDA:MGI.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0048302; P:regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0002456; P:T cell mediated immunity; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.::GO:0002513; P:tolerance induction to self antigen; IMP:MGI. | 219 | Q3BJS1 | 506 | FOXN4_XENLA Forkhead box protein N4 OS=Xenopu... | 84 | 0.0000002 | 56.2 | 32 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 220 | O88621 | 401 | FOXH1_MOUSE Forkhead box protein H1 OS=Mus mu... | 84 | 0.0000003 | 55.5 | 31 | 57 | GO:0032444; C:activin responsive factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0070412; F:R-SMAD binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0048318; P:axial mesoderm development; IMP:MGI.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0042074; P:cell migration involved in gastrulation; IBA:RefGenome.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IMP:MGI.::GO:0021508; P:floor plate formation; IBA:RefGenome.::GO:0001947; P:heart looping; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0010159; P:specification of organ position; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 221 | O70220 | 400 | FOXQ1_MOUSE Forkhead box protein Q1 OS=Mus mu... | 79 | 0.0000003 | 55.5 | 35 | 57 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome. | | | | | | | | | | GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 222 | Q63244 | 399 | FOXQ1_RAT Forkhead box protein Q1 OS=Rattus n... | 79 | 0.0000003 | 55.1 | 35 | 57 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome. | | | | | | | | | | GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031069; P:hair follicle morphogenesis; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 223 | P98177 | 505 | FOXO4_HUMAN Forkhead box protein O4 OS=Homo s... | 119 | 0.0000004 | 55.1 | 34 | 51 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 224 | Q9C009 | 403 | FOXQ1_HUMAN Forkhead box protein Q1 OS=Homo s... | 79 | 0.0000004 | 54.7 | 35 | 57 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome. | | | | | | | | | | GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031069; P:hair follicle morphogenesis; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 225 | Q5VYV0 | 432 | FOXB2_HUMAN Forkhead box protein B2 OS=Homo s... | 78 | 0.0000005 | 54.3 | 35 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007420; P:brain development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 226 | Q64733 | 428 | FOXB2_MOUSE Forkhead box protein B2 OS=Mus mu... | 78 | 0.0000006 | 54.3 | 35 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007420; P:brain development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 227 | P39521 | 936 | FHL1_YEAST Pre-rRNA-processing protein FHL1 O... | 71 | 0.0000009 | 54.3 | 35 | 55 | GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD. | | | | | | | | | | GO:0010688; P:negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0060963; P:positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 228 | A8MYZ6 | 492 | FOXO6_HUMAN Forkhead box protein O6 OS=Homo s... | 109 | 0.0000009 | 53.9 | 32 | 51 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 229 | O75593 | 365 | FOXH1_HUMAN Forkhead box protein H1 OS=Homo s... | 81 | 0.000001 | 52.8 | 31 | 58 | GO:0032444; C:activin responsive factor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0048318; P:axial mesoderm development; IBA:RefGenome.::GO:0001568; P:blood vessel development; IBA:RefGenome.::GO:0042074; P:cell migration involved in gastrulation; IBA:RefGenome.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IBA:RefGenome.::GO:0021508; P:floor plate formation; IBA:RefGenome.::GO:0001947; P:heart looping; IBA:RefGenome.::GO:1900164; P:nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; NAS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0010159; P:specification of organ position; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:UniProtKB. | 230 | Q70KY4 | 559 | FOXO6_MOUSE Forkhead box protein O6 OS=Mus mu... | 109 | 0.000002 | 53.1 | 32 | 51 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.::GO:0016525; P:negative regulation of angiogenesis; IBA:RefGenome.::GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 231 | Q28GC4 | 515 | FOXH1_XENTR Forkhead box protein H1 OS=Xenopu... | 84 | 0.000003 | 52.4 | 30 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0032924; P:activin receptor signaling pathway; ISS:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 232 | Q8JIT7 | 344 | FAST3_XENLA Forkhead activin signal transduce... | 81 | 0.00001 | 50.1 | 30 | 57 | GO:0032444; C:activin responsive factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IPI:UniProtKB. | | | | | | | | | | GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 233 | P70056 | 518 | FOXH1_XENLA Forkhead box protein H1 OS=Xenopu... | 84 | 0.00003 | 49.3 | 29 | 56 | GO:0032444; C:activin responsive factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0032924; P:activin receptor signaling pathway; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007501; P:mesodermal cell fate specification; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 234 | Q9I9E1 | 472 | FOXH1_DANRE Forkhead box protein H1 OS=Danio ... | 83 | 0.00004 | 48.9 | 30 | 54 | GO:0032444; C:activin responsive factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0070412; F:R-SMAD binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:ZFIN.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0048327; P:axial mesodermal cell fate specification; IMP:ZFIN.::GO:0001568; P:blood vessel development; IMP:ZFIN.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:ZFIN.::GO:0042074; P:cell migration involved in gastrulation; IMP:ZFIN.::GO:0009953; P:dorsal/ventral pattern formation; IMP:ZFIN.::GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IBA:RefGenome.::GO:0060971; P:embryonic heart tube left/right pattern formation; IMP:ZFIN.::GO:0001706; P:endoderm formation; IMP:ZFIN.::GO:0021508; P:floor plate formation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:ZFIN.::GO:0014028; P:notochord formation; IMP:ZFIN.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0021501; P:prechordal plate formation; IMP:ZFIN.::GO:2000223; P:regulation of BMP signaling pathway involved in heart jogging; IMP:ZFIN.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0032525; P:somite rostral/caudal axis specification; IMP:ZFIN.::GO:0010159; P:specification of organ position; IMP:ZFIN.::GO:0060063; P:Spemann organizer formation at the embryonic shield; IMP:ZFIN.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 235 | Q3UTB7 | 268 | FOXR1_MOUSE Forkhead box protein R1 OS=Mus mu... | 55 | 0.00004 | 48.1 | 36 | 62 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 236 | Q3UM89 | 302 | FOXR2_MOUSE Forkhead box protein R2 OS=Mus mu... | 60 | 0.0003 | 45.4 | 33 | 55 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 237 | Q28H65 | 293 | FOXN5_XENTR Forkhead box protein N5 OS=Xenopu... | 70 | 0.002 | 42.7 | 29 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 238 | Q6PIV2 | 292 | FOXR1_HUMAN Forkhead box protein R1 OS=Homo s... | 55 | 0.002 | 42.7 | 33 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 239 | Q3BJS0 | 295 | FOXN5_XENLA Forkhead box protein N5 OS=Xenopu... | 74 | 0.003 | 42.7 | 27 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 240 | Q6PJQ5 | 311 | FOXR2_HUMAN Forkhead box protein R2 OS=Homo s... | 68 | 0.019 | 40 | 26 | 50 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 241 | Q19802 | 461 | FKH5_CAEEL Putative forkhead-related transcri... | 60 | 0.021 | 40 | 35 | 52 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. |
