rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | B7N6C8 | 270 | HCAB_ECOLU 3-phenylpropionate-dihydrodiol/cin... | 266 | 0.002 | 42.7 | 26 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 542 | Q28960 | 289 | CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ... | 145 | 0.002 | 42.7 | 22 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 543 | P51657 | 344 | DHB1_RAT Estradiol 17-beta-dehydrogenase 1 OS... | 214 | 0.002 | 42.7 | 26 | 43 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD. | | | | | | | | | | GO:0060348; P:bone development; IEP:RGD.::GO:0071248; P:cellular response to metal ion; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD.::GO:0061370; P:testosterone biosynthetic process; IDA:RGD. | 544 | O75452 | 317 | RDH16_HUMAN Retinol dehydrogenase 16 OS=Homo ... | 200 | 0.002 | 42.7 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006629; P:lipid metabolic process; TAS:ProtInc. | 545 | Q8K354 | 277 | CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu... | 246 | 0.002 | 42.4 | 24 | 38 | | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 546 | Q07530 | 308 | YD114_YEAST Uncharacterized oxidoreductase YD... | 226 | 0.002 | 42.4 | 26 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 547 | Q5BE65 | 369 | TSC10_EMENI 3-ketodihydrosphingosine reductas... | 79 | 0.003 | 42.7 | 29 | 58 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 548 | Q81GI3 | 256 | FABI_BACCR Enoyl-[acyl-carrier-protein] reduc... | 94 | 0.003 | 42.4 | 32 | 50 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.] | 549 | Q96NR8 | 316 | RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo ... | 217 | 0.003 | 42.4 | 26 | 43 | GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 550 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 181 | 0.003 | 42.4 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 551 | P47727 | 277 | CBR1_RAT Carbonyl reductase [NADPH] 1 OS=Ratt... | 128 | 0.003 | 42 | 27 | 44 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0001542; P:ovulation from ovarian follicle; IEP:RGD.::GO:0018205; P:peptidyl-lysine modification; NAS:RGD.::GO:0042376; P:phylloquinone catabolic process; IDA:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 552 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 181 | 0.004 | 42 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 553 | P05707 | 259 | SRLD_ECOLI Sorbitol-6-phosphate 2-dehydrogena... | 261 | 0.004 | 42 | 23 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 554 | Q03326 | 298 | OXIR_STRAT Probable oxidoreductase OS=Strepto... | 224 | 0.004 | 42 | 26 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 555 | Q07588 | 254 | ADH_DROIM Alcohol dehydrogenase OS=Drosophila... | 197 | 0.004 | 41.6 | 23 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 556 | Q70UN9 | 257 | ADH1_CERCO Alcohol dehydrogenase 1 OS=Ceratit... | 199 | 0.004 | 41.6 | 25 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 557 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 261 | 0.005 | 42 | 25 | 41 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 558 | Q59V93 | 349 | MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid... | 251 | 0.005 | 42 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 559 | P16152 | 277 | CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho... | 142 | 0.005 | 41.6 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB. | 560 | O77769 | 302 | DHRS3_BOVIN Short-chain dehydrogenase/reducta... | 177 | 0.005 | 41.6 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 561 | Q3ZBV9 | 255 | DHR11_BOVIN Dehydrogenase/reductase SDR famil... | 261 | 0.005 | 41.6 | 21 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 562 | P80365 | 405 | DHI2_HUMAN Corticosteroid 11-beta-dehydrogena... | 191 | 0.005 | 42 | 25 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc. | 563 | A1C6J8 | 345 | MKAR_ASPCL 3-ketoacyl-CoA reductase OS=3887 /... | 205 | 0.005 | 41.6 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 564 | P0CI32 | 270 | HCAB_ECOLX 3-phenylpropionate-dihydrodiol/cin... | 266 | 0.005 | 41.6 | 26 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 565 | Q5RCU5 | 277 | CBR1_PONAB Carbonyl reductase [NADPH] 1 OS=Po... | 142 | 0.005 | 41.6 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 566 | A4IFM3 | 313 | DR9C7_BOVIN Short-chain dehydrogenase/reducta... | 216 | 0.006 | 41.6 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 567 | Q8CHS7 | 311 | DRS7C_MOUSE Dehydrogenase/reductase SDR famil... | 194 | 0.006 | 41.6 | 24 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 568 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 261 | 0.006 | 41.6 | 25 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 569 | P54398 | 256 | FBP2_DROME Fat body protein 2 OS=Drosophila m... | 189 | 0.006 | 41.2 | 20 | 44 | GO:0005811; C:lipid particle; IDA:FlyBase. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0045735; F:nutrient reservoir activity; NAS:UniProtKB. | | | | | | | | | | | 570 | Q6GI75 | 256 | FABI_STAAR Enoyl-[acyl-carrier-protein] reduc... | 128 | 0.006 | 41.2 | 29 | 48 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.] | 571 | Q6R0J2 | 292 | DHI1_MESAU Corticosteroid 11-beta-dehydrogena... | 170 | 0.007 | 41.2 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. |