rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q83RE8 | 248 | YDFG_SHIFL NADP-dependent L-serine/L-allo-thr... | 183 | 0.000008 | 49.7 | 23 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 422 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 139 | 0.000008 | 50.4 | 27 | 46 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 423 | P45200 | 252 | Y1430_HAEIN Probable NADP-dependent dehydroge... | 187 | 0.000009 | 49.7 | 22 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 424 | Q1RH28 | 262 | FABI_RICBR Enoyl-[acyl-carrier-protein] reduc... | 261 | 0.00001 | 49.7 | 24 | 44 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 425 | A5PJF6 | 330 | HSDL1_BOVIN Inactive hydroxysteroid dehydroge... | 203 | 0.00001 | 50.1 | 24 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 426 | Q53GQ0 | 312 | DHB12_HUMAN Estradiol 17-beta-dehydrogenase 1... | 230 | 0.00001 | 49.7 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. | 427 | Q9ZKW1 | 271 | VDLC_HELPJ Probable short-chain type dehydrog... | 195 | 0.00001 | 49.7 | 24 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 428 | Q8K3P0 | 313 | DR9C7_MOUSE Short-chain dehydrogenase/reducta... | 227 | 0.00001 | 49.7 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 429 | P54795 | 257 | MOAE_ENTAE Protein moaE OS=Enterobacter aerog... | 154 | 0.00001 | 49.3 | 26 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 430 | Q6P7R8 | 312 | DHB12_RAT Estradiol 17-beta-dehydrogenase 12 ... | 201 | 0.00002 | 49.3 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 431 | A5WWC6 | 319 | HSDL1_DANRE Inactive hydroxysteroid dehydroge... | 213 | 0.00002 | 48.9 | 24 | 43 | GO:0005739; C:mitochondrion; IDA:ZFIN. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 432 | Q5RA68 | 418 | HSDL2_PONAB Hydroxysteroid dehydrogenase-like... | 139 | 0.00002 | 49.3 | 27 | 46 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 433 | Q7Z9I2 | 253 | YCP9_SCHPO Uncharacterized oxidoreductase C66... | 202 | 0.00002 | 48.5 | 26 | 45 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 434 | P69936 | 248 | YDFG_SALTY NADP-dependent L-serine/L-allo-thr... | 183 | 0.00002 | 48.5 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 435 | P69935 | 248 | YDFG_SALTI NADP-dependent L-serine/L-allo-thr... | 183 | 0.00002 | 48.5 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 436 | Q6GV12 | 332 | KDSR_MOUSE 3-ketodihydrosphingosine reductase... | 186 | 0.00002 | 48.9 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; IGI:MGI. | 437 | P50170 | 317 | RDH2_RAT Retinol dehydrogenase 2 OS=Rattus no... | 212 | 0.00002 | 48.9 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0042573; P:retinoic acid metabolic process; IDA:RGD.::GO:0042572; P:retinol metabolic process; IDA:RGD. | 438 | P58381 | 268 | FABI2_RHIME Enoyl-[acyl-carrier-protein] redu... | 198 | 0.00003 | 48.1 | 24 | 47 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 439 | P35320 | 297 | OXIR_STRLI Probable oxidoreductase OS=Strepto... | 227 | 0.00004 | 48.1 | 29 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 440 | P48758 | 277 | CBR1_MOUSE Carbonyl reductase [NADPH] 1 OS=Mu... | 143 | 0.00004 | 47.8 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 441 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 175 | 0.00005 | 47.8 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 442 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 251 | 0.00005 | 48.1 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 443 | Q62730 | 381 | DHB2_RAT Estradiol 17-beta-dehydrogenase 2 OS... | 206 | 0.00006 | 47.8 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; IDA:RGD.::GO:0060348; P:bone development; IEP:RGD.::GO:0071248; P:cellular response to metal ion; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD. | 444 | Q83RC9 | 240 | FOLM_SHIFL Dihydrofolate reductase folM OS=Sh... | 199 | 0.00006 | 47.4 | 29 | 43 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 445 | Q0T4H1 | 240 | FOLM_SHIF8 Dihydrofolate reductase folM OS=Sh... | 199 | 0.00006 | 47.4 | 29 | 43 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 446 | Q07587 | 269 | ADHR_DROLE Alcohol dehydrogenase-related 31 k... | 129 | 0.00006 | 47.4 | 26 | 45 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 447 | Q06417 | 326 | TDA5_YEAST Uncharacterized oxidoreductase TDA... | 211 | 0.00007 | 47.4 | 24 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042493; P:response to drug; IMP:SGD. | 448 | Q5R7K0 | 330 | HSDL1_PONAB Inactive hydroxysteroid dehydroge... | 199 | 0.00007 | 47.4 | 25 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 449 | Q3T0R4 | 325 | DRS7B_BOVIN Dehydrogenase/reductase SDR famil... | 205 | 0.00008 | 47.4 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 450 | O75828 | 277 | CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho... | 285 | 0.00008 | 47 | 22 | 38 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | | 451 | P37059 | 387 | DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ... | 206 | 0.00008 | 47.4 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. |