| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8Y3U2 | 229 | NPD_LISMO NAD-dependent protein deacetylase O... | 245 | 4e-17 | 84.3 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 32 | Q5RBF1 | 352 | SIR2_PONAB NAD-dependent protein deacetylase ... | 249 | 9e-17 | 85.1 | 30 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 33 | C8V3W5 | 489 | HST1_EMENI NAD-dependent protein deacetylase ... | 271 | 1e-16 | 86.3 | 30 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 34 | Q8R104 | 257 | SIR3_MOUSE NAD-dependent protein deacetylase ... | 247 | 1e-16 | 83.6 | 30 | 43 | GO:0016020; C:membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0009060; P:aerobic respiration; ISS:UniProtKB.::GO:0034983; P:peptidyl-lysine deacetylation; ISS:UniProtKB. | 35 | Q4R834 | 389 | SIR2_MACFA NAD-dependent protein deacetylase ... | 249 | 1e-16 | 85.1 | 30 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 36 | Q8IXJ6 | 389 | SIR2_HUMAN NAD-dependent protein deacetylase ... | 249 | 2e-16 | 84.7 | 30 | 44 | GO:0005677; C:chromatin silencing complex; NAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0017136; F:NAD-dependent histone deacetylase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000183; P:chromatin silencing at rDNA; NAS:UniProtKB.::GO:0006348; P:chromatin silencing at telomere; NAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045843; P:negative regulation of striated muscle tissue development; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; NAS:UniProtKB.::GO:0007096; P:regulation of exit from mitosis; NAS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; NAS:UniProtKB.::GO:0051775; P:response to redox state; NAS:UniProtKB. | 37 | Q927A7 | 229 | NPD_LISIN NAD-dependent protein deacetylase O... | 245 | 2e-16 | 82.8 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 38 | Q8VDQ8 | 389 | SIR2_MOUSE NAD-dependent protein deacetylase ... | 249 | 2e-16 | 84.3 | 30 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB. | | | | | | | | | | GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0017136; F:NAD-dependent histone deacetylase activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0042903; F:tubulin deacetylase activity; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045843; P:negative regulation of striated muscle tissue development; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 39 | Q9YB13 | 245 | NPD_AERPE NAD-dependent protein deacylase OS=... | 280 | 5e-16 | 81.6 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 40 | B5YJW3 | 256 | NPD_THEYD NAD-dependent protein deacetylase O... | 309 | 6e-16 | 81.3 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 41 | O58669 | 249 | NPD_PYRHO NAD-dependent protein deacylase OS=... | 275 | 6e-16 | 81.3 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 42 | Q8U1Q1 | 250 | NPD_PYRFU NAD-dependent protein deacylase OS=... | 276 | 0.000000000000001 | 80.9 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | Q57V41 | 351 | SIR2_TRYB2 NAD-dependent protein deacetylase ... | 240 | 0.000000000000002 | 81.3 | 28 | 41 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 44 | Q9USN7 | 332 | HST2_SCHPO NAD-dependent protein deacetylase ... | 248 | 0.000000000000002 | 80.9 | 31 | 41 | GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0016585; C:chromatin remodeling complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031934; C:mating-type region heterochromatin; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0033553; C:rDNA heterochromatin; IDA:PomBase.::GO:0031933; C:telomeric heterochromatin; IDA:PomBase. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0017136; F:NAD-dependent histone deacetylase activity; TAS:PomBase.::GO:0003714; F:transcription corepressor activity; IMP:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0000183; P:chromatin silencing at rDNA; IMP:PomBase.::GO:0060303; P:regulation of nucleosome density; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 45 | Q735N7 | 242 | NPD_BACC1 NAD-dependent protein deacetylase O... | 305 | 0.000000000000003 | 79.3 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 46 | Q67KQ0 | 251 | NPD_SYMTH NAD-dependent protein deacetylase O... | 245 | 0.000000000000003 | 79 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 47 | P0CS88 | 354 | HST22_EMENI NAD-dependent protein deacetylase... | 398 | 0.000000000000004 | 80.5 | 25 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 48 | Q7ZVK3 | 379 | SIR2_DANRE NAD-dependent protein deacetylase ... | 258 | 0.000000000000004 | 80.5 | 32 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 49 | Q7P1B9 | 244 | NPD_CHRVO NAD-dependent protein deacetylase O... | 250 | 0.000000000000008 | 77.8 | 29 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 50 | Q5HM33 | 246 | NPD_STAEQ NAD-dependent protein deacetylase O... | 258 | 0.000000000000009 | 77.8 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 51 | Q8ZT00 | 249 | NPD2_PYRAE NAD-dependent protein deacylase 2 ... | 264 | 0.000000000000009 | 77.8 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q54P49 | 456 | SIR2C_DICDI NAD-dependent deacetylase sir2C O... | 256 | 0.00000000000001 | 80.1 | 31 | 44 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 53 | Q8R9N6 | 242 | NPD1_THETN NAD-dependent protein deacylase 1 ... | 249 | 0.00000000000001 | 77.4 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 54 | Q81BT4 | 245 | NPD_BACCR NAD-dependent protein deacetylase O... | 305 | 0.00000000000002 | 77 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 55 | Q8CNF4 | 246 | NPD_STAES NAD-dependent protein deacetylase O... | 258 | 0.00000000000002 | 76.6 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 56 | Q639M6 | 245 | NPD_BACCZ NAD-dependent protein deacetylase O... | 295 | 0.00000000000002 | 76.3 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 57 | Q81NT6 | 242 | NPD_BACAN NAD-dependent protein deacetylase O... | 296 | 0.00000000000003 | 76.3 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 58 | O30124 | 253 | NPD2_ARCFU NAD-dependent protein deacylase 2 ... | 238 | 0.00000000000003 | 76.3 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 59 | Q57YZ9 | 306 | SIR4_TRYB2 NAD-dependent protein deacetylase ... | 285 | 0.00000000000003 | 77 | 26 | 41 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 60 | Q9I4E1 | 256 | NPD2_PSEAE NAD-dependent protein deacylase 2 ... | 215 | 0.00000000000004 | 75.9 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 61 | Q6A5T5 | 244 | NPD_PROAC NAD-dependent protein deacetylase O... | 313 | 0.00000000000004 | 75.9 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |
