rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q8N3Y7 | 309 | RDHE2_HUMAN Epidermal retinol dehydrogenase 2... | 191 | 0.000000002 | 60.8 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050908; P:detection of light stimulus involved in visual perception; NAS:UniProtKB.::GO:0043616; P:keratinocyte proliferation; IMP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 362 | Q9BUT1 | 245 | BDH2_HUMAN 3-hydroxybutyrate dehydrogenase ty... | 161 | 0.000000002 | 60.1 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:HGNC. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:HGNC.::GO:0051287; F:NAD binding; IDA:HGNC.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IDA:HGNC.::GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 363 | Q8BYK4 | 316 | RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m... | 269 | 0.000000002 | 60.8 | 23 | 43 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 364 | P70684 | 265 | PGDH_CAVPO 15-hydroxyprostaglandin dehydrogen... | 194 | 0.000000002 | 60.1 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 365 | P39577 | 252 | DLTE_BACSU Uncharacterized oxidoreductase dlt... | 191 | 0.000000003 | 59.7 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 366 | P38286 | 347 | MKAR_YEAST 3-ketoacyl-CoA reductase OS=Saccha... | 233 | 0.000000003 | 60.5 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045703; F:ketoreductase activity; IPI:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; IPI:SGD. | 367 | Q29529 | 244 | CBR2_PIG Carbonyl reductase [NADPH] 2 OS=Sus ... | 177 | 0.000000003 | 59.7 | 28 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 368 | O16925 | 314 | STDH4_CAEEL Putative steroid dehydrogenase 4 ... | 248 | 0.000000003 | 60.5 | 25 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 369 | A3LXZ3 | 346 | MKAR_PICST 3-ketoacyl-CoA reductase OS=NRRL Y... | 210 | 0.000000003 | 60.5 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 370 | P69167 | 260 | HSD_MYCTU 3-alpha-(or 20-beta)-hydroxysteroid... | 129 | 0.000000004 | 59.7 | 29 | 51 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IDA:MTBBASE.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IDA:MTBBASE. | 371 | P69166 | 260 | HSD_MYCBO 3-alpha-(or 20-beta)-hydroxysteroid... | 129 | 0.000000004 | 59.7 | 29 | 51 | | | | | | | | | | | GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 372 | P50168 | 427 | DHI2_SHEEP Corticosteroid 11-beta-dehydrogena... | 195 | 0.000000004 | 60.5 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 373 | P50197 | 250 | LINC_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,... | 130 | 0.000000004 | 59.3 | 32 | 52 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW. | 374 | Q70UP6 | 258 | ADH2_CERRO Alcohol dehydrogenase 2 OS=Ceratit... | 151 | 0.000000004 | 59.3 | 27 | 46 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 375 | Q7T2D1 | 336 | RD10B_DANRE Retinol dehydrogenase 10-B OS=Dan... | 142 | 0.000000004 | 60.1 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 376 | Q99MZ7 | 303 | PECR_MOUSE Peroxisomal trans-2-enoyl-CoA redu... | 178 | 0.000000004 | 59.7 | 24 | 46 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 377 | O18404 | 255 | HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase ty... | 190 | 0.000000004 | 59.3 | 28 | 46 | GO:0005829; C:cytosol; NAS:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; ISS:UniProtKB. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0047022; F:7-beta-hydroxysteroid dehydrogenase (NADP+) activity; IDA:FlyBase.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:FlyBase.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:FlyBase.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:FlyBase. | | | | | | | | | | GO:0006637; P:acyl-CoA metabolic process; IDA:FlyBase.::GO:0008209; P:androgen metabolic process; IDA:FlyBase.::GO:0008205; P:ecdysone metabolic process; IDA:FlyBase.::GO:0008210; P:estrogen metabolic process; IDA:FlyBase.::GO:0006631; P:fatty acid metabolic process; IDA:FlyBase.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 378 | P0CG22 | 281 | DR4L1_HUMAN Putative dehydrogenase/reductase ... | 194 | 0.000000004 | 59.7 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 379 | A5PJJ7 | 316 | S16C6_BOVIN Short-chain dehydrogenase/reducta... | 257 | 0.000000005 | 59.7 | 25 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 380 | Q91XV4 | 244 | DCXR_MESAU L-xylulose reductase OS=Mesocricet... | 211 | 0.000000005 | 58.9 | 25 | 48 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 381 | Q1JP75 | 244 | DCXR_BOVIN L-xylulose reductase OS=Bos taurus... | 211 | 0.000000005 | 58.9 | 25 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. | 382 | O77667 | 404 | DHI2_BOVIN Corticosteroid 11-beta-dehydrogena... | 195 | 0.000000005 | 60.1 | 27 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 383 | P39644 | 259 | YWFH_BACSU Bacilysin biosynthesis oxidoreduct... | 239 | 0.000000006 | 58.9 | 24 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 384 | Q48436 | 256 | BUDC_KLEPN Diacetyl reductase [(S)-acetoin fo... | 188 | 0.000000006 | 58.9 | 27 | 44 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 385 | O88876 | 302 | DHRS3_MOUSE Short-chain dehydrogenase/reducta... | 152 | 0.000000006 | 59.3 | 27 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 386 | Q556J2 | 334 | KDSR_DICDI 3-ketodihydrosphingosine reductase... | 156 | 0.000000008 | 58.9 | 28 | 46 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase. | 387 | Q9RPT1 | 256 | RHLG_PSEAE Rhamnolipids biosynthesis 3-oxoacy... | 191 | 0.000000008 | 58.5 | 26 | 45 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.] | | | | | | | | | | | 388 | Q12634 | 283 | T4HR_MAGO7 Tetrahydroxynaphthalene reductase ... | 189 | 0.000000008 | 58.9 | 27 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047039; F:tetrahydroxynaphthalene reductase activity; IEA:EC. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 389 | P76633 | 261 | YGCW_ECOLI Uncharacterized oxidoreductase ygc... | 186 | 0.000000009 | 58.5 | 24 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 390 | P50204 | 242 | PHAB_PARDE Acetoacetyl-CoA reductase OS=Parac... | 185 | 0.000000009 | 58.2 | 26 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 391 | O34717 | 254 | FADH_BACSU Probable 2,4-dienoyl-CoA reductase... | 194 | 0.000000009 | 58.2 | 28 | 49 | | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. |