| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q8HWS3 | 928 | RFX6_HUMAN DNA-binding protein RFX6 OS=Homo s... | 82 | 0.14 | 34.3 | 29 | 44 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB. | 2 | P27619 | 877 | DYN_DROME Dynamin OS=Drosophila melanogaster ... | 47 | 0.2 | 33.9 | 38 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase.::GO:0070864; C:sperm individualization complex; IDA:FlyBase.::GO:0045202; C:synapse; IMP:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:FlyBase.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:FlyBase.::GO:0008017; F:microtubule binding; IDA:FlyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0046667; P:compound eye retinal cell programmed cell death; IMP:FlyBase.::GO:0001661; P:conditioned taste aversion; IMP:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0030198; P:extracellular matrix organization; IMP:FlyBase.::GO:0030536; P:larval feeding behavior; IMP:FlyBase.::GO:0045433; P:male courtship behavior, veined wing generated song production; IMP:FlyBase.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:FlyBase.::GO:0008355; P:olfactory learning; IDA:FlyBase.::GO:0007279; P:pole cell formation; TAS:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:FlyBase.::GO:0007637; P:proboscis extension reflex; IMP:FlyBase.::GO:0006898; P:receptor-mediated endocytosis; NAS:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:FlyBase.::GO:0040008; P:regulation of growth; IMP:FlyBase.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0035152; P:regulation of tube architecture, open tracheal system; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0007291; P:sperm individualization; IMP:FlyBase.::GO:0016185; P:synaptic vesicle budding from presynaptic membrane; IMP:FlyBase.::GO:0048499; P:synaptic vesicle membrane organization; IMP:FlyBase. | 3 | Q9UQ16 | 869 | DYN3_HUMAN Dynamin-3 OS=Homo sapiens (Human).... | 79 | 0.36 | 33.1 | 30 | 39 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0007416; P:synapse assembly; ISS:UniProtKB. | 4 | Q9ESR9 | 2434 | ABCA2_RAT ATP-binding cassette sub-family A m... | 87 | 0.49 | 32.7 | 32 | 44 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:UniProtKB.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0032383; P:regulation of intracellular cholesterol transport; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0048545; P:response to steroid hormone stimulus; ISS:UniProtKB.::GO:0006810; P:transport; NAS:UniProtKB. | 5 | Q9FJ62 | 766 | GLPQ1_ARATH Probable glycerophosphoryl dieste... | 62 | 0.62 | 32.3 | 37 | 44 | GO:0046658; C:anchored to plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:EC. | | | | | | | | | | GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.::GO:0010442; P:guard cell morphogenesis; IGI:TAIR.::GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0052541; P:plant-type cell wall cellulose metabolic process; IGI:TAIR.::GO:0010026; P:trichome differentiation; IGI:TAIR. | 6 | Q640R3 | 418 | HECAM_MOUSE Hepatocyte cell adhesion molecule... | 42 | 0.95 | 32 | 40 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 7 | Q92611 | 657 | EDEM1_HUMAN ER degradation-enhancing alpha-ma... | 61 | 1.2 | 31.6 | 31 | 43 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 8 | P25482 | 391 | VE2_HPV2A Regulatory protein E2 OS=Human papi... | 35 | 1.3 | 31.6 | 34 | 46 | GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006275; P:regulation of DNA replication; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro. | 9 | Q6CAP9 | 389 | MMM11_YARLI Maintenance of mitochondrial morp... | 38 | 1.8 | 31.2 | 39 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 10 | Q24145 | 939 | SHARK_DROME Tyrosine-protein kinase shark OS=... | 43 | 2.1 | 30.8 | 42 | 47 | GO:0005938; C:cell cortex; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IEP:UniProtKB. | 11 | Q90941 | 1633 | PB1_CHICK Protein polybromo-1 OS=Gallus gallu... | 108 | 2.2 | 30.8 | 29 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q9VMA7 | 1430 | TGO1_DROME Transport and Golgi organization p... | 36 | 2.5 | 30.8 | 42 | 42 | GO:0070971; C:endoplasmic reticulum exit site; IDA:FlyBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0009306; P:protein secretion; IMP:UniProtKB. | 13 | D2HNW6 | 928 | RFX6_AILME DNA-binding protein RFX6 OS=Ailuro... | 38 | 3.2 | 30.4 | 37 | 50 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.::GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.::GO:0090104; P:pancreatic E cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB. | 14 | A1CJ92 | 1591 | SRB8_ASPCL Mediator of RNA polymerase II tran... | 70 | 4.1 | 30 | 33 | 44 | GO:0016592; C:mediator complex; IEA:InterPro. | | | | | | | | | | GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro. | | | | | | | | | | | 15 | Q8H199 | 658 | CRK14_ARATH Cysteine-rich receptor-like prote... | 57 | 4.3 | 30 | 30 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | O88831 | 587 | KKCC2_RAT Calcium/calmodulin-dependent protei... | 40 | 5.3 | 29.6 | 38 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.::GO:0030295; F:protein kinase activator activity; TAS:RGD. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 17 | Q0WV90 | 1120 | TPR1_ARATH Topless-related protein 1 OS=Arabi... | 74 | 6.3 | 29.6 | 32 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q9UPG8 | 496 | PLAL2_HUMAN Zinc finger protein PLAGL2 OS=Hom... | 65 | 6.3 | 29.6 | 32 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q6W2J9 | 1755 | BCOR_HUMAN BCL-6 corepressor OS=Homo sapiens ... | 93 | 7.6 | 29.3 | 30 | 42 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0031072; F:heat shock protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB. | | | | | | | | | | GO:0007507; P:heart development; IMP:UniProtKB.::GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.::GO:0000415; P:negative regulation of histone H3-K36 methylation; IMP:UniProtKB.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:0070171; P:negative regulation of tooth mineralization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042476; P:odontogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0065001; P:specification of axis polarity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q94AI7 | 1131 | TPL_ARATH Protein TOPLESS OS=Arabidopsis thal... | 78 | 9.4 | 29.3 | 29 | 37 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:TAIR. | | | | | | | | | | GO:0009867; P:jasmonic acid mediated signaling pathway; IMP:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0010072; P:primary shoot apical meristem specification; IMP:TAIR.::GO:0009733; P:response to auxin stimulus; IPI:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010051; P:xylem and phloem pattern formation; IGI:TAIR. |
