| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P18052 | 829 | PTPRA_MOUSE Receptor-type tyrosine-protein ph... | 105 | 1.6 | 33.5 | 24 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 92 | Q64512 | 2453 | PTN13_MOUSE Tyrosine-protein phosphatase non-... | 44 | 1.7 | 33.5 | 34 | 50 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 93 | Q16827 | 1216 | PTPRO_HUMAN Receptor-type tyrosine-protein ph... | 61 | 1.8 | 33.5 | 30 | 51 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0030424; C:axon; ISS:UniProtKB.::GO:0043197; C:dendritic spine; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0016328; C:lateral plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0017147; F:Wnt-protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0002548; P:monocyte chemotaxis; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; ISS:UniProtKB. | 94 | P49445 | 359 | PTN7_RAT Tyrosine-protein phosphatase non-rec... | 62 | 1.8 | 33.1 | 39 | 52 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 95 | O35239 | 593 | PTN9_MOUSE Tyrosine-protein phosphatase non-r... | 65 | 1.9 | 33.1 | 31 | 43 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 96 | P70261 | 859 | PALD_MOUSE Paladin OS=Mus musculus (Mouse). G... | 68 | 2 | 33.1 | 31 | 46 | | | | | | | | | | | | | | | | | | | | | | 97 | P04157 | 1273 | PTPRC_RAT Receptor-type tyrosine-protein phos... | 58 | 2.4 | 33.1 | 36 | 50 | GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; TAS:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0019887; F:protein kinase regulator activity; TAS:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:RGD. | | | | | | | | | | GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:RGD.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 98 | Q79LY0 | 468 | HOPD2_PSESM Effector protein hopD2 OS=Pseudom... | 75 | 2.5 | 32.7 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 99 | P74851 | 543 | SPTP_SALTI Secreted effector protein sptP OS=... | 71 | 2.9 | 32.7 | 30 | 46 | GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 100 | A5DJ85 | 1216 | TOF1_PICGU Topoisomerase 1-associated factor ... | 127 | 2.9 | 32.7 | 23 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. | 101 | P06800 | 1291 | PTPRC_MOUSE Receptor-type tyrosine-protein ph... | 47 | 3.2 | 32.7 | 38 | 49 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 102 | Q86IL4 | 163 | TP4AB_DICDI Probable protein tyrosine phospha... | 122 | 3.3 | 31.6 | 20 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 103 | P29352 | 802 | PTN22_MOUSE Tyrosine-protein phosphatase non-... | 54 | 3.4 | 32.3 | 31 | 52 | GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI. | 104 | O95278 | 331 | EPM2A_HUMAN Laforin OS=Homo sapiens (Human). ... | 58 | 3.7 | 32 | 31 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005844; C:polysome; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:2001070; F:starch binding; IEA:InterPro. | | | | | | | | | | GO:0005977; P:glycogen metabolic process; NAS:UniProtKB. | 105 | Q68CZ2 | 1445 | TENS3_HUMAN Tensin-3 OS=Homo sapiens (Human).... | 46 | 3.7 | 32.3 | 33 | 54 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 106 | Q61152 | 453 | PTN18_MOUSE Tyrosine-protein phosphatase non-... | 44 | 4.7 | 32 | 36 | 57 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 107 | Q16849 | 979 | PTPRN_HUMAN Receptor-type tyrosine-protein ph... | 70 | 6.6 | 31.6 | 36 | 46 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB. | 108 | P56722 | 979 | PTPRN_BOVIN Receptor-type tyrosine-protein ph... | 102 | 7.1 | 31.6 | 31 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB. | 109 | Q60673 | 979 | PTPRN_MOUSE Receptor-type tyrosine-protein ph... | 102 | 7.2 | 31.6 | 31 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI. | 110 | Q9D658 | 173 | TP4A3_MOUSE Protein tyrosine phosphatase type... | 154 | 8.5 | 30.4 | 25 | 41 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 111 | Q63259 | 983 | PTPRN_RAT Receptor-type tyrosine-protein phos... | 102 | 8.5 | 31.2 | 31 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD. | 112 | Q99952 | 460 | PTN18_HUMAN Tyrosine-protein phosphatase non-... | 44 | 9.4 | 30.8 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | |
