rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 54 | 0.039 | 42.4 | 37 | 61 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 392 | A8XI74 | 277 | CED2_CAEBR Cell death abnormality protein 2 O... | 67 | 1 | 37.4 | 34 | 49 | | | | | | | | | | | GO:0032403; F:protein complex binding; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB. | 393 | Q8IS20 | 1457 | GEFC_DICDI Ras guanine nucleotide exchange fa... | 177 | 0.039 | 42.7 | 24 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 394 | Q3SZ01 | 341 | SH3Y1_BOVIN SH3 domain-containing YSC84-like ... | 56 | 0.041 | 42 | 36 | 63 | | | | | | | | | | | | | | | | | | | | | | 395 | O01498 | 457 | STAM1_CAEEL Signal transducing adapter molecu... | 57 | 0.041 | 42.4 | 37 | 60 | GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB. | 396 | P56945 | 870 | BCAR1_HUMAN Breast cancer anti-estrogen resis... | 60 | 0.043 | 42.7 | 35 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; IMP:BHF-UCL.::GO:0051301; P:cell division; NAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 397 | P34109 | 1109 | MYOD_DICDI Myosin ID heavy chain OS=Dictyoste... | 56 | 0.42 | 39.7 | 36 | 57 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 398 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 64 | 0.046 | 42.4 | 36 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 399 | P0CR79 | 660 | HSE1_CRYNB Class E vacuolar protein-sorting m... | 61 | 0.31 | 39.7 | 26 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 400 | Q4VAA7 | 574 | SNX33_MOUSE Sorting nexin-33 OS=Mus musculus ... | 92 | 9.3 | 35 | 25 | 49 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 401 | A7MBI0 | 444 | PACN1_BOVIN Protein kinase C and casein kinas... | 79 | 1.4 | 37.4 | 30 | 52 | | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 402 | Q6YKA8 | 211 | DRK_DROSI Protein E(sev)2B OS=Drosophila simu... | 51 | 0.3 | 38.9 | 35 | 57 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 403 | Q08012 | 211 | DRK_DROME Protein enhancer of sevenless 2B OS... | 51 | 0.3 | 38.9 | 35 | 57 | GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase. | 404 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 49 | 0.059 | 42 | 37 | 61 | | | | | | | | | | | | | | | | | | | | | | 405 | O13736 | 1420 | SLA1_SCHPO Actin cytoskeleton-regulatory comp... | 133 | 0.06 | 42.4 | 29 | 44 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; ISS:PomBase. | 406 | O75791 | 330 | GRAP2_HUMAN GRB2-related adapter protein 2 OS... | 51 | 0.84 | 37.7 | 33 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 407 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 49 | 0.063 | 41.6 | 37 | 61 | | | | | | | | | | | | | | | | | | | | | | 408 | P49710 | 486 | HCLS1_MOUSE Hematopoietic lineage cell-specif... | 49 | 1.5 | 37.4 | 31 | 59 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0032403; F:protein complex binding; IPI:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB. | 409 | Q9UNF0 | 486 | PACN2_HUMAN Protein kinase C and casein kinas... | 56 | 1 | 37.7 | 34 | 57 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; TAS:ProtInc. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 410 | Q6P6U0 | 517 | FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus... | 65 | 0.069 | 41.6 | 34 | 54 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB. | 411 | O13154 | 448 | PACN2_CHICK Protein kinase C and casein kinas... | 58 | 0.44 | 38.9 | 34 | 57 | GO:0005829; C:cytosol; ISS:AgBase.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; ISS:AgBase. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; ISS:AgBase. | 412 | P29366 | 551 | BEM1_YEAST Bud emergence protein 1 OS=Sacchar... | 146 | 0.084 | 41.6 | 23 | 42 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD. | 413 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 64 | 0.084 | 41.6 | 34 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 414 | P34258 | 493 | YKA7_CAEEL Uncharacterized protein B0303.7 OS... | 124 | 0.087 | 41.6 | 23 | 44 | | | | | | | | | | | | | | | | | | | | | | 415 | P13115 | 532 | SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X... | 64 | 0.091 | 41.2 | 34 | 55 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 416 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 54 | 0.095 | 41.6 | 43 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 417 | P13116 | 532 | SRC2_XENLA Tyrosine-protein kinase Src-2 OS=X... | 64 | 0.1 | 41.2 | 34 | 55 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 418 | Q6CTM9 | 380 | END3_KLULA Actin cytoskeleton-regulatory comp... | 69 | 0.11 | 40.8 | 38 | 55 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 419 | Q6WKZ7 | 506 | NOSTN_MOUSE Nostrin OS=Mus musculus (Mouse). ... | 51 | 4.8 | 35.8 | 37 | 57 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 420 | Q9VU84 | 531 | DBNL_DROME Drebrin-like protein OS=Drosophila... | 55 | 0.13 | 40.8 | 33 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IC:UniProtKB. | | | | | | | | | | | 421 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 81 | 0.14 | 40.8 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | |