| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P78621 | 1790 | SEPA_EMENI Cytokinesis protein sepA OS=194 / ... | 802 | 3e-77 | 287 | 29 | 50 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 2 | Q80U19 | 1115 | DAAM2_MOUSE Disheveled-associated activator o... | 364 | 0.000000006 | 65.1 | 23 | 42 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 3 | Q86T65 | 1068 | DAAM2_HUMAN Disheveled-associated activator o... | 425 | 0.0000002 | 60.1 | 21 | 43 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 4 | Q9Y4D1 | 1078 | DAAM1_HUMAN Disheveled-associated activator o... | 310 | 0.00000000006 | 71.2 | 22 | 45 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 5 | Q8BPM0 | 1077 | DAAM1_MOUSE Disheveled-associated activator o... | 318 | 0.0000000001 | 70.5 | 22 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 6 | Q54WH2 | 1218 | FORA_DICDI Formin-A OS=Dictyostelium discoide... | 432 | 0.002 | 46.6 | 22 | 41 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005522; F:profilin binding; ISS:dictyBase.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 7 | Q9Z207 | 1171 | DIAP3_MOUSE Protein diaphanous homolog 3 OS=M... | 313 | 3e-18 | 95.5 | 24 | 48 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 8 | O08808 | 1255 | DIAP1_MOUSE Protein diaphanous homolog 1 OS=M... | 432 | 2e-22 | 108 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0005522; F:profilin binding; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI. | | | | | | | | | | GO:0030041; P:actin filament polymerization; IDA:MGI.::GO:0031175; P:neuron projection development; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW. | 9 | O60610 | 1272 | DIAP1_HUMAN Protein diaphanous homolog 1 OS=H... | 443 | 2e-23 | 112 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0072686; C:mitotic spindle; IDA:BHF-UCL.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0005102; F:receptor binding; NAS:ProtInc.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0071420; P:cellular response to histamine; IMP:BHF-UCL.::GO:0035372; P:protein localization to microtubule; IMP:BHF-UCL.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:BHF-UCL.::GO:0007605; P:sensory perception of sound; TAS:ProtInc. | 10 | Q9NSV4 | 1193 | DIAP3_HUMAN Protein diaphanous homolog 3 OS=H... | 464 | 3e-21 | 104 | 23 | 46 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 11 | P48608 | 1091 | DIA_DROME Protein diaphanous OS=Drosophila me... | 314 | 4e-16 | 88.2 | 25 | 46 | GO:0005912; C:adherens junction; IDA:FlyBase.::GO:0045177; C:apical part of cell; IDA:FlyBase.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0032154; C:cleavage furrow; IDA:FlyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IPI:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0003383; P:apical constriction; IMP:FlyBase.::GO:0007110; P:cytokinesis after meiosis I; IMP:FlyBase.::GO:0007111; P:cytokinesis after meiosis II; IMP:FlyBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:FlyBase.::GO:0032507; P:maintenance of protein location in cell; IMP:FlyBase.::GO:0045448; P:mitotic cell cycle, embryonic; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0009306; P:protein secretion; IMP:FlyBase.::GO:0030589; P:pseudocleavage involved in syncytial blastoderm formation; IMP:FlyBase.::GO:0016476; P:regulation of embryonic cell shape; IMP:FlyBase.::GO:0007605; P:sensory perception of sound; IMP:FlyBase.::GO:0007283; P:spermatogenesis; IMP:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase. | 12 | O60879 | 1101 | DIAP2_HUMAN Protein diaphanous homolog 2 OS=H... | 302 | 0.0000000000007 | 77.8 | 22 | 47 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005102; F:receptor binding; TAS:ProtInc.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW. | 13 | Q27J81 | 1249 | INF2_HUMAN Inverted formin-2 OS=Homo sapiens ... | 297 | 0.000005 | 55.1 | 22 | 45 | GO:0005783; C:endoplasmic reticulum; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 14 | Q9VUC6 | 1183 | Y2138_DROME Formin-like protein CG32138 OS=Dr... | 473 | 5e-28 | 127 | 24 | 46 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 15 | Q9JL26 | 1094 | FMNL_MOUSE Formin-like protein 1 OS=Mus muscu... | 388 | 1e-27 | 126 | 25 | 49 | GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005522; F:profilin binding; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IMP:MGI. | 16 | Q9C0D6 | 1143 | FHDC1_HUMAN FH2 domain-containing protein 1 O... | 383 | 2e-27 | 125 | 26 | 46 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 17 | P41832 | 1953 | BNI1_YEAST Protein BNI1 OS=Saccharomyces cere... | 475 | 2e-27 | 125 | 23 | 46 | GO:0005884; C:actin filament; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0000133; C:polarisome; IPI:SGD.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005522; F:profilin binding; IDA:SGD.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; IMP:SGD.::GO:0045010; P:actin nucleation; IDA:SGD.::GO:0051016; P:barbed-end actin filament capping; IDA:SGD.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:SGD.::GO:0070649; P:formin-nucleated actin cable assembly; IDA:SGD. | 18 | Q5TJ56 | 1220 | FORF_DICDI Formin-F OS=Dictyostelium discoide... | 338 | 0.000000000000001 | 87 | 23 | 48 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005522; F:profilin binding; ISS:dictyBase.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 19 | Q6ZM86 | 1009 | GRD2I_DANRE Delphilin OS=Danio rerio (Zebrafi... | 384 | 2e-26 | 122 | 23 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 20 | Q0QWG9 | 1203 | GRD2I_MOUSE Delphilin OS=Mus musculus (Mouse)... | 387 | 5e-26 | 120 | 22 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:MGI.::GO:0060292; P:long term synaptic depression; IMP:MGI. | 21 | Q10059 | 1841 | CDC12_SCHPO Cell division control protein 12 ... | 474 | 0.00000000001 | 73.9 | 18 | 43 | GO:0005826; C:actomyosin contractile ring; TAS:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; NAS:PomBase.::GO:0045010; P:actin nucleation; TAS:PomBase.::GO:0051016; P:barbed-end actin filament capping; IDA:PomBase.::GO:0051126; P:negative regulation of actin nucleation; TAS:PomBase.::GO:0061164; P:transitional endoplasmic reticulum polarization at cell division site; IMP:PomBase. | 22 | A4D2P6 | 1211 | GRD2I_HUMAN Delphilin OS=Homo sapiens (Human)... | 389 | 7e-26 | 120 | 22 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 23 | Q3ULZ2 | 1149 | FHDC1_MOUSE FH2 domain-containing protein 1 O... | 414 | 2e-25 | 119 | 25 | 45 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 24 | Q0GNC1 | 1273 | INF2_MOUSE Inverted formin-2 OS=Mus musculus ... | 297 | 0.00000007 | 61.2 | 23 | 45 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 25 | Q54ER5 | 2546 | FORJ_DICDI Formin-J OS=Dictyostelium discoide... | 396 | 5e-25 | 117 | 26 | 47 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005522; F:profilin binding; ISS:dictyBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 26 | A2APV2 | 1086 | FMNL2_MOUSE Formin-like protein 2 OS=Mus musc... | 153 | 0.046 | 42.4 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 27 | Q96PY5 | 1086 | FMNL2_HUMAN Formin-like protein 2 OS=Homo sap... | 153 | 0.051 | 42 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 28 | O95466 | 1100 | FMNL_HUMAN Formin-like protein 1 OS=Homo sapi... | 416 | 6e-23 | 110 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB. | 29 | Q54N00 | 1087 | FORH_DICDI Formin-H OS=Dictyostelium discoide... | 276 | 0.0000004 | 58.9 | 21 | 43 | GO:0015629; C:actin cytoskeleton; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0017049; F:GTP-Rho binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase. | | | | | | | | | | GO:0045010; P:actin nucleation; IDA:dictyBase.::GO:0051638; P:barbed-end actin filament uncapping; IDA:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0031268; P:pseudopodium organization; IMP:dictyBase. | 30 | Q10719 | 1372 | FUS1_SCHPO Cell fusion protein fus1 OS=Schizo... | 407 | 0.000000000004 | 75.1 | 22 | 43 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005937; C:mating projection; IDA:PomBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; NAS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0032220; P:plasma membrane fusion involved in cytogamy; IMP:PomBase. | 31 | Q9FJX6 | 899 | FH6_ARATH Formin-like protein 6 OS=Arabidopsi... | 372 | 7e-20 | 100 | 26 | 44 | GO:0005618; C:cell wall; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005819; C:spindle; IDA:TAIR. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. |
