| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O88491 | 2588 | NSD1_MOUSE Histone-lysine N-methyltransferase... | 59 | 0.0005 | 47.8 | 37 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | O94880 | 888 | PHF14_HUMAN PHD finger protein 14 OS=Homo sap... | 49 | 0.21 | 38.9 | 35 | 53 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 63 | Q9D4H9 | 881 | PHF14_MOUSE PHD finger protein 14 OS=Mus musc... | 49 | 0.2 | 38.9 | 35 | 53 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 64 | Q96L73 | 2696 | NSD1_HUMAN Histone-lysine N-methyltransferase... | 59 | 0.0007 | 47.4 | 37 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 65 | Q13342 | 867 | LY10_HUMAN Nuclear body protein SP140 OS=Homo... | 69 | 0.0008 | 47 | 38 | 49 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005635; C:nuclear envelope; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; TAS:ProtInc. | 66 | Q38JA7 | 1556 | KDM5C_CANFA Lysine-specific demethylase 5C OS... | 63 | 1.4 | 36.6 | 35 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 67 | A1YVX4 | 1516 | KDM5C_PIG Lysine-specific demethylase 5C OS=S... | 63 | 1.5 | 36.2 | 35 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 68 | P41229 | 1560 | KDM5C_HUMAN Lysine-specific demethylase 5C OS... | 63 | 1.3 | 36.6 | 35 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 69 | Q9VMJ7 | 1838 | KDM5_DROME Lysine-specific demethylase lid OS... | 35 | 0.85 | 37 | 46 | 63 | GO:0070822; C:Sin3-type complex; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0043992; F:histone acetyltransferase activity (H3-K9 specific); IMP:FlyBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IMP:FlyBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 70 | Q09908 | 538 | PHF2_SCHPO SWM histone demethylase complex su... | 76 | 0.001 | 45.8 | 33 | 47 | GO:0033193; C:Lsd1/2 complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034605; P:cellular response to heat; IEP:PomBase.::GO:0033169; P:histone H3-K9 demethylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 71 | Q9UGL1 | 1544 | KDM5B_HUMAN Lysine-specific demethylase 5B OS... | 62 | 0.54 | 37.7 | 34 | 53 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:GDB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 72 | Q80Y84 | 1544 | KDM5B_MOUSE Lysine-specific demethylase 5B OS... | 62 | 1.4 | 36.6 | 32 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 73 | A6ZZW1 | 594 | BYE1_YEAS7 Transcription factor BYE1 OS=Sacch... | 52 | 0.002 | 45.4 | 35 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 74 | P36106 | 594 | BYE1_YEAST Transcription factor BYE1 OS=Sacch... | 52 | 0.002 | 45.4 | 35 | 58 | GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 75 | Q96PU4 | 802 | UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2... | 33 | 0.77 | 37 | 42 | 67 | GO:0005720; C:nuclear heterochromatin; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEP:HGNC.::GO:0008283; P:cell proliferation; IEP:HGNC.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:HGNC. | 76 | Q5F3R2 | 1522 | KDM5B_CHICK Lysine-specific demethylase 5B OS... | 48 | 0.003 | 45.1 | 40 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 77 | Q96T88 | 793 | UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1... | 47 | 0.026 | 42 | 45 | 62 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IEP:BHF-UCL.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.::GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 78 | P41230 | 1554 | KDM5C_MOUSE Lysine-specific demethylase 5C OS... | 63 | 1.3 | 36.6 | 35 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 79 | Q7TMI3 | 803 | UHRF2_MOUSE E3 ubiquitin-protein ligase UHRF2... | 32 | 0.69 | 37.4 | 44 | 63 | GO:0005720; C:nuclear heterochromatin; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; ISS:HGNC.::GO:0008283; P:cell proliferation; ISS:HGNC.::GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:HGNC. | 80 | Q9HDV4 | 1513 | LID2_SCHPO Lid2 complex component lid2 OS=Sch... | 34 | 0.36 | 38.5 | 47 | 62 | GO:0048189; C:Lid2 complex; IDA:PomBase.::GO:0031934; C:mating-type region heterochromatin; IDA:PomBase.::GO:0031618; C:nuclear centromeric heterochromatin; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:PomBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0031507; P:heterochromatin assembly; IMP:PomBase.::GO:0051567; P:histone H3-K9 methylation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0034630; P:RITS complex localization; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 81 | Q9ULU4 | 1186 | PKCB1_HUMAN Protein kinase C-binding protein ... | 48 | 0.004 | 44.7 | 38 | 54 | GO:0005634; C:nucleus; ISS:BHF-UCL. | | | | | | | | | | GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 82 | P29375 | 1690 | KDM5A_HUMAN Lysine-specific demethylase 5A OS... | 102 | 0.005 | 44.7 | 25 | 43 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 83 | Q3UXZ9 | 1690 | KDM5A_MOUSE Lysine-specific demethylase 5A OS... | 46 | 0.007 | 43.9 | 37 | 59 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 84 | Q96T23 | 1441 | RSF1_HUMAN Remodeling and spacing factor 1 OS... | 40 | 0.36 | 38.5 | 43 | 55 | GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031213; C:RSF complex; IPI:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034080; P:CenH3-containing nucleosome assembly at centromere; TAS:Reactome.::GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0016584; P:nucleosome positioning; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; IDA:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IDA:UniProtKB. | 85 | Q30DN6 | 1545 | KDM5D_CANFA Lysine-specific demethylase 5D OS... | 125 | 5.6 | 34.3 | 30 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 86 | Q8NEZ4 | 4911 | MLL3_HUMAN Histone-lysine N-methyltransferase... | 32 | 1.9 | 36.2 | 44 | 59 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 87 | Q8BRH4 | 4903 | MLL3_MOUSE Histone-lysine N-methyltransferase... | 32 | 2.3 | 35.8 | 44 | 59 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 88 | Q6IQX0 | 1503 | KD5BB_DANRE Lysine-specific demethylase 5B-B ... | 132 | 0.88 | 37 | 29 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 89 | Q9HB58 | 689 | SP110_HUMAN Sp110 nuclear body protein OS=Hom... | 52 | 0.016 | 42.7 | 37 | 46 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 90 | Q9VWF2 | 2006 | SAYP_DROME Supporter of activation of yellow ... | 61 | 0.016 | 42.7 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000791; C:euchromatin; IDA:UniProtKB.::GO:0000792; C:heterochromatin; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005701; C:polytene chromosome chromocenter; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016458; P:gene silencing; IMP:UniProtKB.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0031936; P:negative regulation of chromatin silencing; IGI:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB. | 91 | Q62240 | 1548 | KDM5D_MOUSE Lysine-specific demethylase 5D OS... | 76 | 0.02 | 42.4 | 33 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. |
