| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9ESF1 | 1997 | OTOF_MOUSE Otoferlin OS=Mus musculus (Mouse).... | 96 | 3.8 | 35.8 | 24 | 53 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; IDA:UniProtKB. | 92 | Q9ERC5 | 1993 | OTOF_RAT Otoferlin OS=Rattus norvegicus (Rat)... | 96 | 4.1 | 35.8 | 24 | 53 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB. | 93 | Q9QYJ2 | 834 | RASA3_RAT Ras GTPase-activating protein 3 OS=... | 147 | 0.012 | 43.9 | 24 | 43 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 94 | Q60790 | 834 | RASA3_MOUSE Ras GTPase-activating protein 3 O... | 147 | 0.012 | 43.9 | 24 | 43 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 95 | Q92462 | 767 | PUB1_SCHPO E3 ubiquitin-protein ligase pub1 O... | 72 | 0.012 | 43.9 | 35 | 57 | GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IMP:PomBase. | | | | | | | | | | GO:0060360; P:negative regulation of leucine import in response to ammonium ion; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.::GO:0051453; P:regulation of intracellular pH; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0034762; P:regulation of transmembrane transport; IMP:PomBase. | 96 | Q14644 | 834 | RASA3_HUMAN Ras GTPase-activating protein 3 O... | 184 | 3.5 | 35.8 | 27 | 46 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 97 | P40748 | 588 | SYT3_RAT Synaptotagmin-3 OS=Rattus norvegicus... | 179 | 0.02 | 43.1 | 25 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:RGD.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD. | 98 | P20444 | 672 | KPCA_MOUSE Protein kinase C alpha type OS=Mus... | 98 | 2.9 | 36.2 | 29 | 53 | GO:0030425; C:dendrite; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0002062; P:chondrocyte differentiation; IDA:MGI.::GO:0000188; P:inactivation of MAPK activity; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0050930; P:induction of positive chemotaxis; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0046325; P:negative regulation of glucose import; IMP:MGI.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:MGI.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0030593; P:neutrophil chemotaxis; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050729; P:positive regulation of inflammatory response; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006937; P:regulation of muscle contraction; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:MGI. | 99 | A3KGK3 | 1992 | FR1L4_MOUSE Fer-1-like protein 4 OS=Mus muscu... | 93 | 1.6 | 37.4 | 29 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 100 | Q14184 | 412 | DOC2B_HUMAN Double C2-like domain-containing ... | 75 | 4.4 | 35.4 | 31 | 49 | GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; ISS:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB. | 101 | Q9FVJ3 | 337 | AGD12_ARATH ADP-ribosylation factor GTPase-ac... | 96 | 2.8 | 35.8 | 26 | 50 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 102 | P70169 | 412 | DOC2B_MOUSE Double C2-like domain-containing ... | 75 | 3.9 | 35.4 | 31 | 49 | GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0019905; F:syntaxin binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IMP:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB. | 103 | P05130 | 679 | KPC1_DROME Protein kinase C, brain isozyme OS... | 112 | 0.02 | 43.1 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 104 | Q5SPC5 | 1992 | OTOF_DANRE Otoferlin OS=Danio rerio (Zebrafis... | 111 | 0.021 | 43.5 | 23 | 45 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB. | 105 | Q28013 | 834 | RASA3_BOVIN Ras GTPase-activating protein 3 O... | 147 | 0.021 | 43.1 | 24 | 42 | GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome. | 106 | Q9HC10 | 1997 | OTOF_HUMAN Otoferlin OS=Homo sapiens (Human).... | 125 | 2.1 | 36.6 | 23 | 48 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:ProtInc.::GO:0007605; P:sensory perception of sound; TAS:ProtInc.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB. | 107 | Q9ZT47 | 150 | PP16A_CUCMA 16 kDa phloem protein 1 OS=Cucurb... | 96 | 0.022 | 40.8 | 29 | 47 | | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 108 | Q9NZM1 | 2061 | MYOF_HUMAN Myoferlin OS=Homo sapiens (Human).... | 280 | 5 | 35.4 | 22 | 39 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IDA:UniProtKB. | | | | | | | | | | GO:0008015; P:blood circulation; TAS:ProtInc.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB. | 109 | P05772 | 671 | KPCB_RABIT Protein kinase C beta type OS=Oryc... | 119 | 0.028 | 42.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 110 | P68403 | 671 | KPCB_RAT Protein kinase C beta type OS=Rattus... | 119 | 0.029 | 42.7 | 28 | 45 | GO:0031526; C:brush border membrane; IDA:RGD.::GO:0005813; C:centrosome; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042488; P:positive regulation of odontogenesis of dentin-containing tooth; IEP:RGD.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0014059; P:regulation of dopamine secretion; IMP:RGD.::GO:0040008; P:regulation of growth; IMP:RGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042493; P:response to drug; IMP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0033280; P:response to vitamin D; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 111 | P68404 | 671 | KPCB_MOUSE Protein kinase C beta type OS=Mus ... | 119 | 0.029 | 42.7 | 28 | 45 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:MGI.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 112 | P05126 | 671 | KPCB_BOVIN Protein kinase C beta type OS=Bos ... | 119 | 0.029 | 42.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 113 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 136 | 0.03 | 42.7 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 114 | Q9T053 | 858 | PLDG1_ARATH Phospholipase D gamma 1 OS=Arabid... | 61 | 0.038 | 42.4 | 41 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:TAIR.::GO:0004630; F:phospholipase D activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0009816; P:defense response to bacterium, incompatible interaction; IGI:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006643; P:membrane lipid metabolic process; IMP:TAIR.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.::GO:0010044; P:response to aluminum ion; IMP:TAIR.::GO:0006979; P:response to oxidative stress; IMP:TAIR. | 115 | Q69ZN7 | 2048 | MYOF_MOUSE Myoferlin OS=Mus musculus (Mouse).... | 83 | 5.1 | 35.4 | 30 | 58 | GO:0005901; C:caveola; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IMP:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0001778; P:plasma membrane repair; IMP:UniProtKB.::GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB. | 116 | Q86XP0 | 818 | PA24D_HUMAN Cytosolic phospholipase A2 delta ... | 79 | 0.046 | 42 | 30 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC. | | | | | | | | | | GO:0009395; P:phospholipid catabolic process; IEA:InterPro. | 117 | Q9UBL6 | 633 | CPNE7_HUMAN Copine-7 OS=Homo sapiens (Human).... | 160 | 4.7 | 35.4 | 24 | 41 | | | | | | | | | | | GO:0005215; F:transporter activity; TAS:ProtInc. | | | | | | | | | | GO:0006629; P:lipid metabolic process; TAS:ProtInc. | 118 | Q96J02 | 903 | ITCH_HUMAN E3 ubiquitin-protein ligase Itchy ... | 87 | 3.4 | 35.8 | 24 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0045236; F:CXCR chemokine receptor binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0090085; P:regulation of protein deubiquitination; ISS:BHF-UCL.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0046718; P:viral entry into host cell; TAS:UniProtKB. | 119 | Q54E35 | 570 | GACEE_DICDI Rho GTPase-activating protein gac... | 125 | 1.5 | 37 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 120 | B2RUP2 | 1085 | UN13D_MOUSE Protein unc-13 homolog D OS=Mus m... | 106 | 0.056 | 42 | 27 | 40 | GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:MGI.::GO:0002467; P:germinal center formation; IMP:MGI.::GO:0002432; P:granuloma formation; IMP:MGI.::GO:0043320; P:natural killer cell degranulation; IMP:MGI.::GO:0006909; P:phagocytosis; IMP:MGI. | 121 | P27715 | 2155 | UNC13_CAEEL Phorbol ester/diacylglycerol-bind... | 143 | 0.47 | 38.9 | 24 | 43 | GO:0048786; C:presynaptic active zone; IDA:WormBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase. |
