| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q5RBF2 | 959 | NED4L_PONAB E3 ubiquitin-protein ligase NEDD4... | 135 | 0.022 | 43.1 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 32 | Q96PU5 | 975 | NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4... | 135 | 0.026 | 42.7 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB. | 33 | Q8CFI0 | 1004 | NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4... | 135 | 0.022 | 43.1 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 34 | Q55CH0 | 654 | ADCC_DICDI Arrestin domain-containing protein... | 123 | 0.00008 | 50.8 | 30 | 50 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 35 | Q9R0N7 | 403 | SYT7_MOUSE Synaptotagmin-7 OS=Mus musculus (M... | 221 | 0.014 | 43.1 | 24 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0001778; P:plasma membrane repair; IDA:MGI. | 36 | O95294 | 804 | RASL1_HUMAN RasGAP-activating-like protein 1 ... | 201 | 3.2 | 36.2 | 22 | 41 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 37 | P24506 | 439 | SY62_DISOM Synaptotagmin-B OS=Discopyge ommat... | 224 | 1 | 37.4 | 21 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 38 | Q7ZV43 | 276 | TOLIP_DANRE Toll-interacting protein OS=Danio... | 112 | 3.7 | 35 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 39 | P46097 | 422 | SYT2_MOUSE Synaptotagmin-2 OS=Mus musculus (M... | 224 | 1.4 | 37 | 20 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0042598; C:vesicular fraction; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 40 | P46935 | 887 | NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4... | 136 | 0.009 | 44.3 | 27 | 48 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI. | | | | | | | | | | GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI. | | | | | | | | | | GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB. | 41 | Q5M7N9 | 889 | ESYT3_XENTR Extended synaptotagmin-3 OS=Xenop... | 73 | 0.0008 | 47.8 | 38 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 42 | Q9FGS8 | 1027 | C2GR2_ARATH C2 and GRAM domain-containing pro... | 47 | 6.3 | 35 | 38 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 43 | Q62940 | 887 | NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 O... | 143 | 0.008 | 44.3 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006955; P:immune response; IEP:RGD.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB. | 44 | Q0JBH9 | 144 | ERG3_ORYSJ Elicitor-responsive protein 3 OS=O... | 123 | 0.0001 | 47.4 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | | 45 | Q25AG5 | 144 | ERG3_ORYSI Elicitor-responsive protein 3 OS=O... | 123 | 0.0001 | 47.4 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | | 46 | A2RUW1 | 274 | TOLIP_RAT Toll-interacting protein OS=Rattus ... | 113 | 2.9 | 35.4 | 22 | 44 | GO:0016604; C:nuclear body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005150; F:interleukin-1, Type I receptor binding; IPI:RGD.::GO:0032183; F:SUMO binding; IPI:RGD.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; IDA:RGD. | 47 | P29101 | 422 | SYT2_RAT Synaptotagmin-2 OS=Rattus norvegicus... | 224 | 1.5 | 37 | 20 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD. | 48 | Q9VVI3 | 1007 | NEDD4_DROME E3 ubiquitin-protein ligase Nedd-... | 83 | 0.016 | 43.5 | 31 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB. | 49 | O23078 | 927 | PLDB2_ARATH Phospholipase D beta 2 OS=Arabido... | 93 | 0.0002 | 50.1 | 35 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.::GO:0004630; F:phospholipase D activity; IDA:TAIR. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro. | 50 | Q8N9I0 | 419 | SYT2_HUMAN Synaptotagmin-2 OS=Homo sapiens (H... | 224 | 1.7 | 36.6 | 20 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; TAS:Reactome. | 51 | C1BZR1 | 275 | TOLIP_ESOLU Toll-interacting protein OS=Esox ... | 77 | 0.9 | 37 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 52 | Q9QZ06 | 274 | TOLIP_MOUSE Toll-interacting protein OS=Mus m... | 113 | 3.1 | 35.4 | 22 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 53 | Q9H0E2 | 274 | TOLIP_HUMAN Toll-interacting protein OS=Homo ... | 113 | 1.9 | 36.2 | 22 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0045323; C:interleukin-1 receptor complex; NAS:UniProtKB.::GO:0045092; C:interleukin-18 receptor complex; NAS:UniProtKB. | | | | | | | | | | GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:UniProtKB.::GO:0035325; F:Toll-like receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006954; P:inflammatory response; NAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0045321; P:leukocyte activation; NAS:UniProtKB.::GO:0016310; P:phosphorylation; IDA:UniProtKB. | 54 | B5X370 | 275 | TOLIP_SALSA Toll-interacting protein OS=Salmo... | 79 | 1.9 | 36.2 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 55 | Q925C0 | 491 | SYT9_RAT Synaptotagmin-9 OS=Rattus norvegicus... | 114 | 0.23 | 39.7 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030667; C:secretory granule membrane; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0050796; P:regulation of insulin secretion; IMP:RGD. | 56 | Q9R0N9 | 491 | SYT9_MOUSE Synaptotagmin-9 OS=Mus musculus (M... | 114 | 0.23 | 39.7 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 57 | Q5ZK05 | 274 | TOLIP_CHICK Toll-interacting protein OS=Gallu... | 113 | 2.1 | 35.8 | 22 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 58 | Q2LGB5 | 273 | TOLIP_BOVIN Toll-interacting protein OS=Bos t... | 132 | 2.9 | 35.4 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0016310; P:phosphorylation; ISS:UniProtKB. | 59 | P47191 | 424 | SYT1_CHICK Synaptotagmin-1 OS=Gallus gallus (... | 224 | 0.63 | 38.1 | 21 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 60 | Q9R0N5 | 386 | SYT5_MOUSE Synaptotagmin-5 OS=Mus musculus (M... | 182 | 0.022 | 42.7 | 26 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 61 | Q86SS6 | 491 | SYT9_HUMAN Synaptotagmin-9 OS=Homo sapiens (H... | 114 | 2.1 | 36.6 | 27 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | |
