| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A4II46 | 862 | ABR_XENTR Active breakpoint cluster region-re... | 214 | 2e-17 | 90.5 | 33 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 32 | Q8CGF1 | 1266 | RHG29_MOUSE Rho GTPase-activating protein 29 ... | 188 | 3e-17 | 90.5 | 35 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 33 | Q5VT97 | 1194 | SYDE2_HUMAN Rho GTPase-activating protein SYD... | 183 | 3e-17 | 90.5 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 34 | Q5SSL4 | 859 | ABR_MOUSE Active breakpoint cluster region-re... | 218 | 3e-17 | 90.1 | 33 | 45 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 35 | Q96P48 | 1450 | ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 199 | 3e-17 | 90.1 | 34 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 36 | Q9HF75 | 2071 | BEM2_ASHGO GTPase-activating protein BEM2 OS=... | 190 | 4e-17 | 90.1 | 33 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 37 | A6QNS3 | 859 | ABR_BOVIN Active breakpoint cluster region-re... | 200 | 4e-17 | 89.4 | 35 | 46 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 38 | Q12979 | 859 | ABR_HUMAN Active breakpoint cluster region-re... | 200 | 5e-17 | 89.4 | 35 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 39 | Q52LW3 | 1261 | RHG29_HUMAN Rho GTPase-activating protein 29 ... | 169 | 6e-17 | 89.4 | 36 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 40 | Q8N264 | 748 | RHG24_HUMAN Rho GTPase-activating protein 24 ... | 167 | 7e-17 | 88.6 | 34 | 51 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 41 | Q5ZMM3 | 475 | RHG15_CHICK Rho GTPase-activating protein 15 ... | 174 | 8e-17 | 87.8 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 42 | Q9V9S7 | 1866 | SYDE_DROME Rho GTPase-activating protein 100F... | 150 | 8e-17 | 89.4 | 35 | 54 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0048786; C:presynaptic active zone; IDA:FlyBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 43 | Q9P107 | 970 | GMIP_HUMAN GEM-interacting protein OS=Homo sa... | 196 | 1e-16 | 88.6 | 32 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:HGNC.::GO:0005100; F:Rho GTPase activator activity; IDA:HGNC. | | | | | | | | | | GO:0034259; P:negative regulation of Rho GTPase activity; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 44 | Q5PQJ5 | 1266 | RHG29_RAT Rho GTPase-activating protein 29 OS... | 188 | 1e-16 | 88.6 | 35 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 45 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 199 | 2e-16 | 88.2 | 34 | 50 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 46 | Q8AVG0 | 862 | ABR_XENLA Active breakpoint cluster region-re... | 214 | 2e-16 | 87.4 | 32 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 47 | Q9VIS1 | 1843 | CDGAP_DROME GTPase-activating protein CdGAPr ... | 214 | 2e-16 | 87.8 | 30 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 48 | Q6AYC5 | 482 | RHG15_RAT Rho GTPase-activating protein 15 OS... | 174 | 2e-16 | 86.3 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 49 | Q6GPD0 | 1940 | RHG32_XENLA Rho GTPase-activating protein 32 ... | 228 | 3e-16 | 87.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 50 | O14559 | 1287 | RHG33_HUMAN Rho GTPase-activating protein 33 ... | 181 | 4e-16 | 86.7 | 30 | 50 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 51 | O14014 | 969 | RGA3_SCHPO Probable Rho-type GTPase-activatin... | 168 | 4e-16 | 86.7 | 32 | 52 | GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 52 | Q20498 | 759 | RRC1_CAEEL GTPase-activating protein rrc-1 OS... | 205 | 5e-16 | 85.9 | 31 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 53 | Q80YF9 | 1305 | RHG33_MOUSE Rho GTPase-activating protein 33 ... | 181 | 6e-16 | 86.3 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 54 | A7YY57 | 1269 | RHG29_BOVIN Rho GTPase-activating protein 29 ... | 188 | 0.000000000000001 | 85.1 | 32 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 55 | O94466 | 695 | RGA7_SCHPO Probable Rho-GTPase-activating pro... | 176 | 0.000000000000001 | 84.7 | 30 | 50 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 56 | Q6PCS4 | 1337 | RHG29_DANRE Rho GTPase-activating protein 29 ... | 185 | 0.000000000000001 | 85.1 | 32 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 57 | Q3TBD2 | 1116 | HMHA1_MOUSE Minor histocompatibility protein ... | 216 | 0.000000000000001 | 85.1 | 31 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 58 | Q03070 | 295 | CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ... | 149 | 0.000000000000002 | 81.6 | 35 | 52 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 59 | Q811P8 | 2089 | RHG32_MOUSE Rho GTPase-activating protein 32 ... | 208 | 0.000000000000002 | 84.7 | 27 | 48 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 60 | A7KAX9 | 2087 | RHG32_HUMAN Rho GTPase-activating protein 32 ... | 243 | 0.000000000000002 | 84.7 | 25 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 61 | Q80XD1 | 332 | CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo... | 149 | 0.000000000000002 | 81.6 | 35 | 52 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |
