| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P37058 | 310 | DHB3_HUMAN Testosterone 17-beta-dehydrogenase... | 216 | 0.00003 | 48.1 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030539; P:male genitalia development; TAS:ProtInc. | 182 | Q8NEX9 | 313 | DR9C7_HUMAN Short-chain dehydrogenase/reducta... | 207 | 0.00003 | 48.1 | 24 | 46 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | | 183 | P70385 | 305 | DHB3_MOUSE Testosterone 17-beta-dehydrogenase... | 192 | 0.00003 | 48.1 | 27 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 184 | O07575 | 289 | YHDF_BACSU Uncharacterized oxidoreductase yhd... | 188 | 0.00003 | 47.8 | 26 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 185 | P50161 | 262 | VER1_ASPPA Versicolorin reductase OS=Aspergil... | 194 | 0.00003 | 47.8 | 25 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 186 | Q28960 | 289 | CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ... | 125 | 0.00004 | 47.8 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 187 | Q9PKF7 | 248 | FABG_CHLMU 3-oxoacyl-[acyl-carrier-protein] r... | 209 | 0.00004 | 47.4 | 21 | 47 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 188 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 198 | 0.00004 | 47.8 | 27 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 189 | Q60V51 | 316 | LE767_CAEBR Putative steroid dehydrogenase le... | 197 | 0.00004 | 47.8 | 27 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0042303; P:molting cycle; ISS:UniProtKB.::GO:0032350; P:regulation of hormone metabolic process; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 190 | P50169 | 317 | RDH3_RAT Retinol dehydrogenase 3 OS=Rattus no... | 209 | 0.00004 | 47.8 | 24 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC. | | | | | | | | | | | 191 | Q6Q7D1 | 287 | DHI1L_BOVIN Hydroxysteroid 11-beta-dehydrogen... | 185 | 0.00004 | 47.4 | 28 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 192 | Q5KTS5 | 291 | GRDH_DAUCA Glucose and ribitol dehydrogenase ... | 211 | 0.00004 | 47.4 | 26 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 193 | P16152 | 277 | CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho... | 127 | 0.00005 | 47.4 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB. | 194 | Q6QLL4 | 300 | DHI1_CAVPO Corticosteroid 11-beta-dehydrogena... | 201 | 0.00005 | 47.4 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 195 | Q17704 | 315 | STDH3_CAEEL Putative steroid dehydrogenase 3 ... | 210 | 0.00005 | 47.4 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 196 | Q49117 | 248 | Y182_METEA Uncharacterized oxidoreductase Mex... | 202 | 0.00005 | 47 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 197 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 188 | 0.00005 | 47.4 | 27 | 46 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 198 | Q5R7K0 | 330 | HSDL1_PONAB Inactive hydroxysteroid dehydroge... | 191 | 0.00006 | 47.4 | 25 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 199 | Q1WNP0 | 328 | DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 ... | 184 | 0.00006 | 47 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro. | 200 | Q9WYG0 | 251 | Y325_THEMA Uncharacterized oxidoreductase TM_... | 195 | 0.00006 | 47 | 25 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 201 | P55006 | 317 | RDH7_RAT Retinol dehydrogenase 7 OS=Rattus no... | 209 | 0.00006 | 47 | 24 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC. | | | | | | | | | | | 202 | O54939 | 306 | DHB3_RAT Testosterone 17-beta-dehydrogenase 3... | 226 | 0.00007 | 47 | 25 | 45 | GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD. | 203 | Q8K9J5 | 244 | FABG_BUCAP 3-oxoacyl-[acyl-carrier-protein] r... | 198 | 0.00007 | 46.6 | 26 | 48 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 204 | P37694 | 287 | HETN_NOSS1 Ketoacyl reductase hetN OS=Nostoc ... | 190 | 0.00007 | 46.6 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043158; P:heterocyst differentiation; IEA:UniProtKB-KW. | 205 | Q3KPT7 | 245 | BDH2_XENLA 3-hydroxybutyrate dehydrogenase ty... | 192 | 0.00008 | 46.6 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 206 | P51657 | 344 | DHB1_RAT Estradiol 17-beta-dehydrogenase 1 OS... | 204 | 0.00008 | 47 | 27 | 49 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD. | | | | | | | | | | GO:0060348; P:bone development; IEP:RGD.::GO:0071248; P:cellular response to metal ion; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD.::GO:0061370; P:testosterone biosynthetic process; IDA:RGD. | 207 | Q6Q7D2 | 287 | DHI1L_MACFA Hydroxysteroid 11-beta-dehydrogen... | 188 | 0.00009 | 46.6 | 29 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 208 | P50164 | 260 | TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamu... | 191 | 0.0001 | 46.2 | 25 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC. | | | | | | | | | | | 209 | P97852 | 735 | DHB4_RAT Peroxisomal multifunctional enzyme t... | 221 | 0.0001 | 47 | 24 | 44 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; NAS:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.] | 210 | P19337 | 249 | BAIA2_EUBSP Bile acid 7-dehydroxylase 2 OS=Eu... | 200 | 0.0001 | 46.2 | 26 | 45 | | | | | | | | | | | GO:0033792; F:bile-acid 7alpha-dehydroxylase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 211 | P51660 | 735 | DHB4_MOUSE Peroxisomal multifunctional enzyme... | 196 | 0.0001 | 47 | 24 | 45 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IDA:MGI. | | | | | | | | | | GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0060009; P:Sertoli cell development; IMP:MGI.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:MGI. |
