rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | Q8K9Q6 | 260 | FABI_BUCAP Enoyl-[acyl-carrier-protein] reduc... | 182 | 0.16 | 36.6 | 24 | 46 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.::GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 542 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 166 | 0.17 | 36.2 | 28 | 47 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 543 | Q50L96 | 256 | ADH_DROAN Alcohol dehydrogenase OS=Drosophila... | 205 | 0.19 | 36.2 | 26 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; ISS:UniProtKB. | 544 | Q9ZMN7 | 275 | FABI_HELPJ Enoyl-[acyl-carrier-protein] reduc... | 249 | 0.21 | 36.2 | 22 | 41 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 545 | P28483 | 256 | ADH_DROER Alcohol dehydrogenase OS=Drosophila... | 197 | 0.21 | 36.2 | 25 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 546 | A6RBW9 | 339 | MKAR_AJECN 3-ketoacyl-CoA reductase OS=(Histo... | 176 | 0.21 | 36.2 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 547 | Q9QYF1 | 316 | RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus m... | 210 | 0.22 | 36.2 | 21 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001917; C:photoreceptor inner segment; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB. | 548 | Q5ZJG8 | 331 | HSDL1_CHICK Hydroxysteroid dehydrogenase-like... | 199 | 0.23 | 36.2 | 25 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 549 | Q03326 | 298 | OXIR_STRAT Probable oxidoreductase OS=Strepto... | 203 | 0.24 | 35.8 | 28 | 38 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 550 | Q24641 | 256 | ADH_DROSI Alcohol dehydrogenase OS=Drosophila... | 197 | 0.26 | 35.8 | 26 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 551 | Q9GN94 | 256 | ADH_DROSE Alcohol dehydrogenase OS=Drosophila... | 197 | 0.26 | 35.8 | 26 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 552 | Q8R536 | 262 | SPRE_MERUN Sepiapterin reductase OS=Meriones ... | 232 | 0.26 | 35.8 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro. | 553 | O54939 | 306 | DHB3_RAT Testosterone 17-beta-dehydrogenase 3... | 195 | 0.26 | 35.8 | 23 | 43 | GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD. | 554 | P00334 | 256 | ADH_DROME Alcohol dehydrogenase OS=Drosophila... | 197 | 0.26 | 35.8 | 26 | 40 | GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IMP:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:FlyBase. | | | | | | | | | | GO:0046164; P:alcohol catabolic process; IMP:UniProtKB.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase. | 555 | P07159 | 256 | ADH_DROOR Alcohol dehydrogenase OS=Drosophila... | 197 | 0.27 | 35.8 | 25 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 556 | O57314 | 312 | DHB12_ANAPL Estradiol 17-beta-dehydrogenase 1... | 200 | 0.27 | 35.8 | 22 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 557 | P35270 | 261 | SPRE_HUMAN Sepiapterin reductase OS=Homo sapi... | 210 | 0.28 | 35.8 | 25 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0050661; F:NADP binding; TAS:UniProtKB.::GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006809; P:nitric oxide biosynthetic process; IDA:UniProtKB.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; TAS:UniProtKB. | 558 | P39831 | 248 | YDFG_ECOLI NADP-dependent 3-hydroxy acid dehy... | 251 | 0.29 | 35.4 | 25 | 41 | | | | | | | | | | | GO:0035527; F:3-hydroxypropionate dehydrogenase (NADP+) activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IDA:EcoCyc. | | | | | | | | | | GO:0006212; P:uracil catabolic process; IMP:EcoCyc. | 559 | Q8X505 | 248 | YDFG_ECO57 NADP-dependent L-serine/L-allo-thr... | 251 | 0.29 | 35.4 | 25 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 560 | Q07586 | 273 | ADHR_DROIM Alcohol dehydrogenase-related 31 k... | 180 | 0.29 | 35.8 | 23 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 561 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 202 | 0.3 | 35.8 | 22 | 43 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 562 | O54753 | 317 | H17B6_RAT 17-beta-hydroxysteroid dehydrogenas... | 232 | 0.31 | 35.8 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; TAS:RGD. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:RGD. | 563 | A9UM79 | 311 | DRS7C_XENTR Dehydrogenase/reductase SDR famil... | 199 | 0.31 | 35.8 | 22 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 564 | A0PJE2 | 317 | DHR12_HUMAN Dehydrogenase/reductase SDR famil... | 91 | 0.31 | 35.8 | 29 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 565 | Q9ZFE4 | 265 | FABI_PSEAE Enoyl-[acyl-carrier-protein] reduc... | 196 | 0.33 | 35.4 | 27 | 42 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 566 | Q7Z5J1 | 315 | DHI1L_HUMAN Hydroxysteroid 11-beta-dehydrogen... | 164 | 0.38 | 35.4 | 24 | 38 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 567 | P35320 | 297 | OXIR_STRLI Probable oxidoreductase OS=Strepto... | 178 | 0.38 | 35.4 | 28 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 568 | P18297 | 262 | SPRE_RAT Sepiapterin reductase OS=Rattus norv... | 231 | 0.42 | 35 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010033; P:response to organic substance; IMP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:RGD. | 569 | Q28960 | 289 | CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ... | 146 | 0.47 | 35 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 570 | P56937 | 341 | DHB7_HUMAN 3-keto-steroid reductase OS=Homo s... | 95 | 0.47 | 35 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 571 | Q6WAU1 | 314 | IPIPR_MENPI (-)-isopiperitenone reductase OS=... | 92 | 0.48 | 35 | 26 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052581; F:(-)-isopiperitenone reductase activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | GO:0031525; P:menthol biosynthetic process; IDA:UniProtKB. |