Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
182136
Length:
1226
Number of sequences:
10438
Description:
estExt_fgenesh2_pm.C_10331
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q66HA1    850   M3K11_RAT Mitogen-activated protein kinase ki...580.82     37.7     36     60GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IPI:RGD.
GO:0008219; P:cell death; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
362Q07839    416   EG13_ECHGR Antigen EG13 OS=Echinococcus granu...1080.83     37.4     31     42
363Q64355    560   EFS_MOUSE Embryonal Fyn-associated substrate ...690.87     37.4     29     54
GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
364Q16584    847   M3K11_HUMAN Mitogen-activated protein kinase ...580.9     37.4     36     60GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:UniProtKB.::GO:0007017; P:microtubule-based process; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
365Q8CJ53    603   CIP4_MOUSE Cdc42-interacting protein 4 OS=Mus...630.91     37.4     38     63GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; TAS:MGI.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
366Q2KEW0    304   SHO1_MAGO7 High osmolarity signaling protein ...1191     37     32     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
367P33832    271   A4_VAR67 39kDa core protein OS=Variola virus ...1241.1     36.6     23     44GO:0019012; C:virion; IEA:UniProtKB-SubCell.
368P19174    1290   PLCG1_HUMAN 1-phosphatidylinositol 4,5-bispho...1171.1     37.4     26     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
369O14302    886   CYK3_SCHPO cytokinesis protein 3 OS=Schizosac...631.1     37.4     30     54GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.
GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.
370P39743    482   RV167_YEAST Reduced viability upon starvation...521.1     37     35     60GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.
371Q6GPJ9    229   GRB2B_XENLA Growth factor receptor-bound prot...531.8     35.8     30     66GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.
GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
372Q9H6S3    715   ES8L2_HUMAN Epidermal growth factor receptor ...981.2     37     27     45GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
373Q07883    217   GRB2_CHICK Growth factor receptor-bound prote...535.2     34.3     30     64GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
374P86963    337   KCP2_PINMA BPTI/Kunitz domain-containing prot...341.2     36.6     50     59GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
375O70145    525   NCF2_MOUSE Neutrophil cytosol factor 2 OS=Mus...911.2     37     27     47GO:0001669; C:acrosomal vesicle; IDA:MGI.
GO:0048365; F:Rac GTPase binding; IPI:MGI.
GO:0042554; P:superoxide anion generation; IDA:MGI.
376A1IGU4    676   ARH37_MOUSE Rho guanine nucleotide exchange f...1021.3     37     27     42GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
377Q64434    451   PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus m...571.3     37     35     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0060575; P:intestinal epithelial cell differentiation; IMP:UniProtKB.::GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB.
378Q6BVC2    304   SHO1_DEBHA High osmolarity signaling protein ...581.3     36.6     38     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
379Q9R1Z8    733   VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ...641.4     37     34     53GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
380Q60631    217   GRB2_MOUSE Growth factor receptor-bound prote...561.8     35.4     32     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0012506; C:vesicle membrane; IDA:MGI.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI.
GO:0048646; P:anatomical structure formation involved in morphogenesis; IMP:MGI.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0043408; P:regulation of MAPK cascade; IGI:MGI.
381Q5RC07    716   ES8L2_PONAB Epidermal growth factor receptor ...981.4     37     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
382P62994    217   GRB2_RAT Growth factor receptor-bound protein...561.7     35.8     32     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0001784; F:phosphotyrosine binding; IPI:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0007568; P:aging; IPI:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0007265; P:Ras protein signal transduction; TAS:RGD.
383Q5R4J7    217   GRB2_PONAB Growth factor receptor-bound prote...561.7     35.8     32     52GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
384P62993    217   GRB2_HUMAN Growth factor receptor-bound prote...561.7     35.8     32     52GO:0005829; C:cytosol; TAS:HGNC.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0070436; C:Grb2-EGFR complex; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.::GO:0031623; P:receptor internalization; IMP:BHF-UCL.::GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome.
385O77775    527   NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos...911.4     36.6     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
386Q9WVE9    1217   ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ...713.2     35.8     34     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD.
387Q5VV41    709   ARHGG_HUMAN Rho guanine nucleotide exchange f...631.5     36.6     32     59GO:0005829; C:cytosol; TAS:Reactome.
GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0032864; P:activation of Cdc42 GTPase activity; IDA:BHF-UCL.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
388O42287    1270   ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (...439.2     34.3     26     65GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
389Q99M51    377   NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu...771.6     36.2     32     48GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI.
GO:0019904; F:protein domain specific binding; IPI:MGI.
GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
390Q14562    1220   DHX8_HUMAN ATP-dependent RNA helicase DHX8 OS...671.6     36.6     37     54GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
391Q63767    968   BCAR1_RAT Breast cancer anti-estrogen resista...431.6     36.6     33     63GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
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