| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q6WKZ7 | 506 | NOSTN_MOUSE Nostrin OS=Mus musculus (Mouse). ... | 108 | 0.0004 | 48.1 | 30 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 242 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 51 | 0.017 | 42.7 | 39 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 243 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 74 | 0.0005 | 48.1 | 30 | 57 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 244 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 51 | 0.018 | 42.7 | 39 | 65 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 245 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 51 | 0.021 | 42.4 | 39 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 246 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 152 | 0.0006 | 48.1 | 30 | 45 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 247 | O77774 | 392 | NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos... | 40 | 0.043 | 41.6 | 35 | 73 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB. | 248 | Q8K4I3 | 771 | ARHG6_MOUSE Rho guanine nucleotide exchange f... | 63 | 0.001 | 47.4 | 32 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 249 | Q5XXR3 | 772 | ARHG6_RAT Rho guanine nucleotide exchange fac... | 63 | 0.001 | 47 | 32 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 250 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 76 | 0.72 | 37.7 | 30 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 251 | Q14155 | 803 | ARHG7_HUMAN Rho guanine nucleotide exchange f... | 61 | 0.001 | 46.6 | 33 | 56 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 252 | O89032 | 1124 | SPD2A_MOUSE SH3 and PX domain-containing prot... | 76 | 0.73 | 37.7 | 30 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 253 | O43586 | 416 | PPIP1_HUMAN Proline-serine-threonine phosphat... | 59 | 0.002 | 46.2 | 36 | 61 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome. | 254 | Q2KJB5 | 505 | NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G... | 102 | 0.002 | 46.2 | 31 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 255 | A6ZKU1 | 1244 | SLA1_YEAS7 Actin cytoskeleton-regulatory comp... | 63 | 0.003 | 45.4 | 43 | 62 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 256 | P32790 | 1244 | SLA1_YEAST Actin cytoskeleton-regulatory comp... | 63 | 0.004 | 45.4 | 43 | 62 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD. | 257 | Q5ZLR6 | 764 | ARHG6_CHICK Rho guanine nucleotide exchange f... | 61 | 0.005 | 45.1 | 31 | 57 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 258 | Q15052 | 776 | ARHG6_HUMAN Rho guanine nucleotide exchange f... | 63 | 0.006 | 44.7 | 30 | 57 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 259 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 68 | 0.006 | 43.5 | 38 | 54 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 260 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 59 | 0.006 | 44.7 | 34 | 59 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 261 | P97814 | 415 | PPIP1_MOUSE Proline-serine-threonine phosphat... | 127 | 0.006 | 44.3 | 24 | 45 | GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI. | 262 | P32793 | 468 | YSC84_YEAST Protein YSC84 OS=Saccharomyces ce... | 57 | 0.008 | 43.9 | 35 | 61 | GO:0030479; C:actin cortical patch; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD. | 263 | P27870 | 845 | VAV_MOUSE Proto-oncogene vav OS=Mus musculus ... | 71 | 0.009 | 43.9 | 34 | 59 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI. | | | | | | | | | | GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI. | 264 | Q12929 | 822 | EPS8_HUMAN Epidermal growth factor receptor k... | 71 | 0.011 | 43.9 | 35 | 55 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc. | 265 | Q5R4H4 | 822 | EPS8_PONAB Epidermal growth factor receptor k... | 71 | 0.011 | 43.9 | 35 | 55 | | | | | | | | | | | | | | | | | | | | | | 266 | P15498 | 845 | VAV_HUMAN Proto-oncogene vav OS=Homo sapiens ... | 71 | 0.013 | 43.5 | 34 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 267 | Q96B97 | 665 | SH3K1_HUMAN SH3 domain-containing kinase-bind... | 56 | 0.015 | 43.1 | 36 | 66 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB. | 268 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 122 | 0.016 | 42.7 | 29 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 269 | Q08DN7 | 844 | VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B... | 71 | 0.016 | 43.1 | 34 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 270 | Q8K3E5 | 1047 | AHI1_MOUSE Jouberin OS=Mus musculus (Mouse). ... | 129 | 0.017 | 43.1 | 29 | 46 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0035844; P:cloaca development; IGI:UniProtKB.::GO:0001947; P:heart looping; IGI:UniProtKB.::GO:0030902; P:hindbrain development; IGI:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0071599; P:otic vesicle development; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; IMP:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; IGI:UniProtKB.::GO:0033365; P:protein localization to organelle; IMP:UniProtKB.::GO:0050795; P:regulation of behavior; IMP:UniProtKB.::GO:0010842; P:retina layer formation; IGI:UniProtKB.::GO:0065001; P:specification of axis polarity; IGI:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB. | 271 | O60861 | 476 | GAS7_HUMAN Growth arrest-specific protein 7 O... | 64 | 0.017 | 42.7 | 38 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc. |
