| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
961 | O08874 | 985 | PKN2_RAT Serine/threonine-protein kinase N2 O... | 207 | 0.000000004 | 64.3 | 27 | 41 | GO:0043296; C:apical junction complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0043297; P:apical junction assembly; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 962 | P90980 | 682 | KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh... | 207 | 0.000000004 | 64.3 | 28 | 42 | GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 963 | Q8BWW9 | 983 | PKN2_MOUSE Serine/threonine-protein kinase N2... | 217 | 0.000000004 | 64.3 | 28 | 41 | GO:0043296; C:apical junction complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 964 | P51955 | 445 | NEK2_HUMAN Serine/threonine-protein kinase Ne... | 177 | 0.000000004 | 63.5 | 30 | 42 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051299; P:centrosome separation; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 965 | Q7ZYJ0 | 1001 | TAO1B_XENLA Serine/threonine-protein kinase T... | 191 | 0.000000004 | 64.3 | 29 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 966 | Q59S66 | 530 | IPL1_CANAL Spindle assembly checkpoint kinase... | 306 | 0.000000004 | 63.9 | 22 | 39 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 967 | Q55A09 | 1331 | Y9963_DICDI Probable serine/threonine-protein... | 215 | 0.000000004 | 64.3 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 968 | Q15759 | 364 | MK11_HUMAN Mitogen-activated protein kinase 1... | 196 | 0.000000004 | 63.2 | 27 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 969 | P25333 | 603 | HAL4_YEAST Serine/threonine-protein kinase HA... | 303 | 0.000000005 | 63.9 | 25 | 36 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IMP:SGD.::GO:0034613; P:cellular protein localization; IGI:SGD.::GO:0006470; P:protein dephosphorylation; IMP:SGD. | 970 | Q8WU08 | 396 | ST32A_HUMAN Serine/threonine-protein kinase 3... | 205 | 0.000000005 | 63.2 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 971 | Q5KQF5 | 451 | CIPKM_ORYSJ CBL-interacting protein kinase 22... | 234 | 0.000000005 | 63.5 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 972 | Q8SSH1 | 516 | Y255_ENCCU Probable serine/threonine-protein ... | 215 | 0.000000005 | 63.5 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 973 | Q3U1V8 | 1077 | M3K9_MOUSE Mitogen-activated protein kinase k... | 276 | 0.000000005 | 64.3 | 25 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 974 | O42626 | 623 | NRC2_NEUCR Serine/threonine-protein kinase nr... | 299 | 0.000000005 | 63.9 | 24 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 975 | Q63638 | 3259 | SPEG_RAT Striated muscle-specific serine/thre... | 251 | 0.000000007 | 63.9 | 24 | 39 | GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042692; P:muscle cell differentiation; IEP:RGD. | 976 | Q62407 | 3262 | SPEG_MOUSE Striated muscle-specific serine/th... | 251 | 0.000000009 | 63.5 | 24 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 977 | Q15772 | 3267 | SPEG_HUMAN Striated muscle preferentially exp... | 305 | 0.00000001 | 63.2 | 23 | 39 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 978 | P10666 | 629 | KS6AB_XENLA Ribosomal protein S6 kinase 2 bet... | 212 | 0.0000001 | 58.9 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 979 | O14236 | 537 | NOG2_SCHPO Nucleolar GTP-binding protein 2 OS... | 122 | 0.0000003 | 57.8 | 28 | 51 | GO:0005730; C:nucleolus; ISS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase. | | | | | | | | | | GO:0000055; P:ribosomal large subunit export from nucleus; ISS:PomBase. | 980 | Q9C3Z4 | 483 | NOG2_PNECA Nucleolar GTP-binding protein 2 OS... | 94 | 0.000001 | 55.5 | 30 | 52 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 981 | Q696W0 | 2995 | SPEG_DANRE Striated muscle preferentially exp... | 234 | 0.000001 | 57 | 27 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:ZFIN. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007517; P:muscle organ development; ISS:ZFIN. | 982 | Q6CSP9 | 513 | NOG2_KLULA Nucleolar GTP-binding protein 2 OS... | 121 | 0.000002 | 55.1 | 25 | 50 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 983 | Q8MT06 | 581 | GNL3_DROME Guanine nucleotide-binding protein... | 129 | 0.000002 | 55.5 | 29 | 53 | GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB. | | | | | | | | | | GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IMP:FlyBase.::GO:0040014; P:regulation of multicellular organism growth; IMP:FlyBase. | 984 | Q9Z2B9 | 773 | KS6A4_MOUSE Ribosomal protein S6 kinase alpha... | 285 | 0.000002 | 55.1 | 26 | 41 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 985 | O75676 | 772 | KS6A4_HUMAN Ribosomal protein S6 kinase alpha... | 286 | 0.000004 | 54.7 | 25 | 41 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; IGI:UniProtKB.::GO:0004711; F:ribosomal protein S6 kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 986 | Q75DA4 | 502 | NOG2_ASHGO Nucleolar GTP-binding protein 2 OS... | 141 | 0.000006 | 53.5 | 26 | 49 | GO:0005730; C:nucleolus; ISS:RefGenome. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:RefGenome. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 987 | Q7SHR8 | 619 | NOG2_NEUCR Nucleolar GTP-binding protein 2 OS... | 123 | 0.000006 | 53.9 | 28 | 47 | GO:0005730; C:nucleolus; ISS:RefGenome. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:RefGenome. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 988 | P53742 | 486 | NOG2_YEAST Nucleolar GTP-binding protein 2 OS... | 142 | 0.000008 | 53.1 | 25 | 49 | GO:0005730; C:nucleolus; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.::GO:0030687; C:preribosome, large subunit precursor; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD. | 989 | Q8CI11 | 538 | GNL3_MOUSE Guanine nucleotide-binding protein... | 89 | 0.00002 | 51.6 | 30 | 54 | GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB. | 990 | Q8J109 | 720 | NOG2_CRYNV Nucleolar GTP-binding protein 2 OS... | 94 | 0.00003 | 51.2 | 24 | 52 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. | 991 | Q6FWS1 | 494 | NOG2_CANGA Nucleolar GTP-binding protein 2 OS... | 95 | 0.00005 | 50.8 | 25 | 53 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. |
