| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P47125 | 453 | I23O_YEAST Indoleamine 2,3-dioxygenase family... | 453 | 3e-41 | 159 | 31 | 47 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD. | | | | | | | | | | GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD. | 2 | P14902 | 403 | I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=... | 443 | 2e-38 | 149 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome. | 3 | Q9ERD9 | 407 | I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra... | 460 | 1e-37 | 147 | 28 | 46 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD. | 4 | Q8R0V5 | 398 | I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=... | 439 | 2e-33 | 134 | 28 | 45 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q6ZQW0 | 407 | I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=... | 383 | 3e-33 | 134 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB. | 6 | P28776 | 407 | I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=... | 442 | 5e-33 | 133 | 28 | 44 | GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI. | 7 | Q01966 | 378 | MYG_HALDV Myoglobin OS=Haliotis diversicolor ... | 376 | 3e-22 | 102 | 27 | 44 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | P51537 | 378 | MYG_HALMK Myoglobin OS=Haliotis madaka (Giant... | 380 | 1e-21 | 100 | 27 | 43 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q6NRL4 | 325 | GET4A_XENLA Golgi to ER traffic protein 4 hom... | 81 | 1.7 | 34.7 | 36 | 51 | GO:0071818; C:BAT3 complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 10 | A4QNE0 | 325 | GET4_XENTR Golgi to ER traffic protein 4 homo... | 81 | 1.8 | 34.7 | 36 | 51 | GO:0071818; C:BAT3 complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 11 | A7TMC5 | 491 | ATG23_VANPO Autophagy-related protein 23 OS=(... | 80 | 4.3 | 33.9 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
