rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P28178 | 479 | PK2_DICDI Protein kinase 2 OS=Dictyostelium d... | 55 | 2.5 | 35 | 42 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 152 | Q8CEE6 | 1383 | PASK_MOUSE PAS domain-containing serine/threo... | 50 | 2.5 | 35.4 | 40 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045719; P:negative regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IMP:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; IMP:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; IMP:UniProtKB. | 153 | Q9WVS4 | 420 | MOK_MOUSE MAPK/MAK/MRK overlapping kinase OS=... | 53 | 2.6 | 35 | 25 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 154 | Q8SSV3 | 652 | MKCD_DICDI Probable serine/threonine-protein ... | 57 | 2.6 | 35 | 35 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 155 | O75385 | 1050 | ULK1_HUMAN Serine/threonine-protein kinase UL... | 44 | 2.8 | 35.4 | 36 | 61 | GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB. | 156 | P15442 | 1659 | GCN2_YEAST Serine/threonine-protein kinase GC... | 42 | 2.8 | 35.4 | 43 | 62 | GO:0022626; C:cytosolic ribosome; IDA:SGD. | | | | | | | | | | GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW. | 157 | Q12701 | 592 | KSG1_SCHPO Serine/threonine-protein kinase ks... | 42 | 2.8 | 35 | 36 | 67 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 158 | Q19192 | 1077 | E2AK3_CAEEL Eukaryotic translation initiation... | 55 | 2.9 | 35.4 | 31 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0002119; P:nematode larval development; IGI:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; IEP:WormBase.::GO:0045948; P:positive regulation of translational initiation; IGI:WormBase.::GO:0010939; P:regulation of necrotic cell death; IGI:WormBase. | 159 | Q39008 | 608 | M3K1_ARATH Mitogen-activated protein kinase k... | 47 | 2.9 | 35 | 34 | 60 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0019900; F:kinase binding; IPI:TAIR.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IDA:TAIR. | 160 | P54739 | 543 | PKAA_STRCO Serine/threonine-protein kinase pk... | 54 | 2.9 | 35 | 30 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 161 | Q39030 | 471 | KPK2_ARATH Serine/threonine-protein kinase At... | 41 | 2.9 | 35 | 41 | 68 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR. | 162 | Q15831 | 433 | STK11_HUMAN Serine/threonine-protein kinase S... | 29 | 3 | 35 | 38 | 76 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0001944; P:vasculature development; ISS:UniProtKB. | 163 | Q8BK63 | 337 | KC1A_MOUSE Casein kinase I isoform alpha OS=M... | 80 | 3 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000902; P:cell morphogenesis; IGI:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 164 | P48729 | 337 | KC1A_HUMAN Casein kinase I isoform alpha OS=H... | 80 | 3 | 34.7 | 34 | 51 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016607; C:nuclear speck; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 165 | P67963 | 337 | KC1A_XENLA Casein kinase I isoform alpha OS=X... | 80 | 3.1 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 166 | P67962 | 337 | KC1A_CHICK Casein kinase I isoform alpha OS=G... | 80 | 3.1 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 167 | Q54HD2 | 2112 | NDRD_DICDI Probable serine/threonine-protein ... | 52 | 3.1 | 35 | 42 | 58 | GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 168 | Q558U1 | 2258 | IFKA_DICDI Probable serine/threonine-protein ... | 93 | 3.1 | 35 | 28 | 47 | GO:0005622; C:intracellular; IC:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IMP:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.::GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.::GO:0048255; P:mRNA stabilization; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0006446; P:regulation of translational initiation; ISS:dictyBase. | 169 | Q75L42 | 454 | CIPKH_ORYSJ CBL-interacting protein kinase 17... | 155 | 3.1 | 35 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 170 | Q550L8 | 1358 | IFKB_DICDI Probable serine/threonine-protein ... | 93 | 3.2 | 35 | 27 | 48 | GO:0005622; C:intracellular; IC:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase. | 171 | Q54PB4 | 481 | MYLKE_DICDI Probable myosin light chain kinas... | 43 | 3.2 | 34.7 | 33 | 63 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 172 | P67829 | 325 | KC1A_SHEEP Casein kinase I isoform alpha OS=O... | 80 | 3.2 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 173 | P67828 | 325 | KC1A_RABIT Casein kinase I isoform alpha OS=O... | 80 | 3.2 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 174 | P67827 | 325 | KC1A_BOVIN Casein kinase I isoform alpha OS=B... | 80 | 3.2 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 175 | Q91819 | 408 | AURAB_XENLA Aurora kinase A-B OS=Xenopus laev... | 50 | 3.3 | 34.7 | 36 | 56 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB. | 176 | Q552C6 | 635 | ZAK2_DICDI Dual specificity protein kinase za... | 49 | 3.4 | 35 | 37 | 59 | | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0042659; P:regulation of cell fate specification; IMP:dictyBase.::GO:0010468; P:regulation of gene expression; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 177 | P97633 | 325 | KC1A_RAT Casein kinase I isoform alpha OS=Rat... | 80 | 3.5 | 34.7 | 34 | 51 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0051219; F:phosphoprotein binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 178 | P54735 | 505 | SPKD_SYNY3 Serine/threonine-protein kinase D ... | 40 | 3.5 | 34.7 | 40 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 179 | P30291 | 646 | WEE1_HUMAN Wee1-like protein kinase OS=Homo s... | 93 | 3.5 | 34.7 | 30 | 47 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome. | 180 | Q5UPU3 | 546 | YL268_MIMIV Putative serine/threonine-protein... | 51 | 3.5 | 34.7 | 33 | 59 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 181 | Q91604 | 432 | STK11_XENLA Serine/threonine-protein kinase s... | 29 | 3.6 | 34.7 | 38 | 76 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0001944; P:vasculature development; ISS:UniProtKB. |