| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P08684 | 503 | CP3A4_HUMAN Cytochrome P450 3A4 OS=Homo sapie... | 283 | 0.0000001 | 57.8 | 23 | 46 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0047638; F:albendazole monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0050591; F:quinine 3-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IDA:BHF-UCL.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 152 | Q9V4U7 | 509 | C6A14_DROME Probable cytochrome P450 6a14 OS=... | 175 | 0.0000001 | 57.8 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 153 | O15528 | 508 | CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydro... | 225 | 0.0000001 | 57.8 | 25 | 43 | GO:0005741; C:mitochondrial outer membrane; TAS:Reactome. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0030282; P:bone mineralization; IEP:BHF-UCL.::GO:0055074; P:calcium ion homeostasis; IMP:BHF-UCL.::GO:0006816; P:calcium ion transport; ISS:BHF-UCL.::GO:0046697; P:decidualization; IEP:BHF-UCL.::GO:0070314; P:G1 to G0 transition; IMP:BHF-UCL.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:BHF-UCL.::GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IEP:BHF-UCL.::GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IEP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IEP:BHF-UCL.::GO:0033280; P:response to vitamin D; IEP:BHF-UCL.::GO:0042368; P:vitamin D biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 154 | O35132 | 501 | CP27B_RAT 25-hydroxyvitamin D-1 alpha hydroxy... | 225 | 0.0000001 | 57.4 | 24 | 45 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; IDA:RGD.::GO:0007595; P:lactation; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0046688; P:response to copper ion; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0032868; P:response to insulin stimulus; IDA:RGD.::GO:0034695; P:response to prostaglandin E stimulus; IDA:RGD.::GO:0033280; P:response to vitamin D; IDA:RGD.::GO:0042369; P:vitamin D catabolic process; IDA:BHF-UCL. | 155 | O65786 | 504 | C71B4_ARATH Cytochrome P450 71B4 OS=Arabidops... | 220 | 0.0000001 | 57.4 | 22 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 156 | O65012 | 553 | C78A4_PINRA Cytochrome P450 78A4 OS=Pinus rad... | 227 | 0.0000001 | 57.4 | 22 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 157 | P10611 | 510 | CP4A4_RABIT Cytochrome P450 4A4 OS=Oryctolagu... | 192 | 0.0000001 | 57.4 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 158 | P48418 | 506 | C75A1_PETHY Flavonoid 3',5'-hydroxylase 1 OS=... | 237 | 0.0000001 | 57.4 | 22 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 159 | Q9STL0 | 483 | C71AN_ARATH Cytochrome P450 71A23 OS=Arabidop... | 234 | 0.0000002 | 57 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | | 160 | P93846 | 492 | CP51_SORBI Obtusifoliol 14-alpha demethylase ... | 397 | 0.0000002 | 57 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 161 | Q92087 | 518 | CP19A_ORYLA Cytochrome P450 19A1 OS=Oryzias l... | 290 | 0.0000002 | 57 | 22 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 162 | P93149 | 523 | C93B1_GLYEC Licodione synthase OS=Glycyrrhiza... | 263 | 0.0000002 | 57 | 21 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033771; F:licodione synthase activity; IEA:EC. | | | | | | | | | | | 163 | P38364 | 506 | PID6_FUSSO Pisatin demethylase OS=Fusarium so... | 179 | 0.0000002 | 56.6 | 25 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 164 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 193 | 0.0000002 | 56.6 | 22 | 42 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 165 | Q9STL1 | 490 | C71AM_ARATH Cytochrome P450 71A22 OS=Arabidop... | 212 | 0.0000002 | 56.6 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 166 | P98183 | 495 | C71DC_CATRO Tabersonine 16-hydroxylase OS=Cat... | 275 | 0.0000002 | 56.6 | 25 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050594; F:tabersonine 16-hydroxylase activity; IEA:EC. | | | | | | | | | | | 167 | P48416 | 545 | CP10_LYMST Cytochrome P450 10 OS=Lymnaea stag... | 238 | 0.0000002 | 56.6 | 22 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 168 | P14580 | 510 | CP4A6_RABIT Cytochrome P450 4A6 OS=Oryctolagu... | 192 | 0.0000002 | 56.6 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 169 | P79401 | 503 | CP3AT_PIG Cytochrome P450 3A29 OS=Sus scrofa ... | 192 | 0.0000002 | 56.2 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 170 | P58049 | 496 | C71BB_ARATH Cytochrome P450 71B11 OS=Arabidop... | 344 | 0.0000003 | 56.2 | 20 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 171 | Q9LIP5 | 500 | C71BW_ARATH Cytochrome P450 71B35 OS=Arabidop... | 218 | 0.0000003 | 56.2 | 20 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 172 | Q9GJX5 | 504 | CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro... | 193 | 0.0000003 | 56.2 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC. | | | | | | | | | | | 173 | Q5IZM4 | 452 | CP51_MYCVP Lanosterol 14-alpha demethylase OS... | 231 | 0.0000003 | 55.8 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 174 | Q9AR74 | 506 | TCMO_RUTGR Trans-cinnamate 4-monooxygenase OS... | 179 | 0.0000003 | 55.8 | 25 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | | 175 | O65438 | 499 | C71AR_ARATH Cytochrome P450 71A27 OS=Arabidop... | 217 | 0.0000003 | 55.8 | 23 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 176 | P33268 | 503 | CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas... | 192 | 0.0000003 | 55.8 | 24 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 177 | Q964T1 | 501 | CP4CU_BLAGE Cytochrome P450 4c21 OS=Blattella... | 266 | 0.0000004 | 55.8 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 178 | Q9LIP3 | 500 | C71BY_ARATH Cytochrome P450 71B37 OS=Arabidop... | 210 | 0.0000004 | 55.8 | 19 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 179 | Q64417 | 503 | CP3AE_CAVPO Cytochrome P450 3A14 OS=Cavia por... | 189 | 0.0000004 | 55.8 | 23 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 180 | O48923 | 510 | C71DA_SOYBN Cytochrome P450 71D10 OS=Glycine ... | 239 | 0.0000004 | 55.8 | 23 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 181 | O23976 | 490 | C76B1_HELTU 7-ethoxycoumarin O-deethylase OS=... | 276 | 0.0000004 | 55.5 | 24 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |
