| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | C0LGI2 | 929 | Y1677_ARATH Probable LRR receptor-like serine... | 200 | 6e-17 | 90.1 | 35 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 512 | Q13164 | 816 | MK07_HUMAN Mitogen-activated protein kinase 7... | 253 | 6e-17 | 90.1 | 27 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 513 | F1N9Y5 | 613 | KSYK_CHICK Tyrosine-protein kinase SYK OS=Gal... | 308 | 6e-17 | 89.4 | 25 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032009; C:early phagosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IMP:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.::GO:0071226; P:cellular response to molecule of fungal origin; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0007159; P:leukocyte cell-cell adhesion; ISS:UniProtKB.::GO:0001945; P:lymph vessel development; ISS:UniProtKB.::GO:0002281; P:macrophage activation involved in immune response; ISS:UniProtKB.::GO:0002283; P:neutrophil activation involved in immune response; ISS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.::GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0090237; P:regulation of arachidonic acid secretion; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043313; P:regulation of neutrophil degranulation; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0032928; P:regulation of superoxide anion generation; ISS:UniProtKB.::GO:0002554; P:serotonin secretion by platelet; ISS:UniProtKB. | 514 | Q9SRH7 | 490 | Y3130_ARATH Receptor-like serine/threonine-pr... | 336 | 7e-17 | 89 | 29 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 515 | O22042 | 651 | M3K3_ARATH Mitogen-activated protein kinase k... | 284 | 7e-17 | 89.4 | 28 | 45 | GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 516 | Q8TDX7 | 302 | NEK7_HUMAN Serine/threonine-protein kinase Ne... | 199 | 7e-17 | 86.7 | 31 | 49 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 517 | Q00993 | 888 | UFO_MOUSE Tyrosine-protein kinase receptor UF... | 322 | 7e-17 | 89.7 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IGI:UniProtKB.::GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0031668; P:cellular response to extracellular stimulus; IDA:MGI.::GO:0007167; P:enzyme linked receptor protein signaling pathway; IGI:MGI.::GO:0034101; P:erythrocyte homeostasis; IMP:MGI.::GO:0021885; P:forebrain cell migration; IGI:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IGI:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0042698; P:ovulation cycle; IGI:MGI.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.::GO:0032940; P:secretion by cell; IMP:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:MGI. | 518 | Q03963 | 515 | E2AK2_MOUSE Interferon-induced, double-strand... | 207 | 7e-17 | 89 | 32 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IDA:MGI.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:MGI.::GO:0033689; P:negative regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006412; P:translation; IDA:MGI.::GO:0006926; P:virus-infected cell apoptotic process; IDA:MGI. | 519 | Q90413 | 922 | FGFR4_DANRE Fibroblast growth factor receptor... | 307 | 7e-17 | 89.7 | 27 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:ZFIN.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 520 | O65472 | 690 | CRK12_ARATH Putative cysteine-rich receptor-l... | 234 | 7e-17 | 89.4 | 32 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 521 | Q8S9L6 | 679 | CRK29_ARATH Cysteine-rich receptor-like prote... | 206 | 7e-17 | 89.4 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR. | 522 | Q5VP69 | 501 | MPK16_ORYSJ Mitogen-activated protein kinase ... | 288 | 8e-17 | 88.6 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 523 | Q7Z8E9 | 914 | STE20_MAGO7 Serine/threonine-protein kinase M... | 202 | 8e-17 | 89.7 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 524 | Q8NEV4 | 1616 | MYO3A_HUMAN Myosin-IIIa OS=Homo sapiens (Huma... | 274 | 8e-17 | 90.1 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030898; F:actin-dependent ATPase activity; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0060002; F:plus-end directed microfilament motor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 525 | Q6YY75 | 534 | NEK6_ORYSJ Serine/threonine-protein kinase Ne... | 203 | 8e-17 | 89 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 526 | Q9LVL5 | 571 | WNK4_ARATH Probable serine/threonine-protein ... | 226 | 8e-17 | 89 | 31 | 48 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 527 | Q09YI9 | 1384 | MET_SHEEP Hepatocyte growth factor receptor O... | 280 | 8e-17 | 90.1 | 24 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 528 | Q61527 | 1308 | ERBB4_MOUSE Receptor tyrosine-protein kinase ... | 283 | 8e-17 | 90.1 | 25 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0061026; P:cardiac muscle tissue regeneration; IMP:UniProtKB.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0021551; P:central nervous system morphogenesis; IMP:UniProtKB.::GO:0009880; P:embryonic pattern specification; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0007595; P:lactation; IMP:UniProtKB.::GO:0060749; P:mammary gland alveolus development; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; IMP:UniProtKB.::GO:0021889; P:olfactory bulb interneuron differentiation; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:2000366; P:positive regulation of STAT protein import into nucleus; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB. | 529 | Q53UA7 | 898 | TAOK3_RAT Serine/threonine-protein kinase TAO... | 279 | 8e-17 | 89.7 | 31 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB. | 530 | O09127 | 1004 | EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus m... | 285 | 9e-17 | 89.7 | 27 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016322; P:neuron remodeling; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. | 531 | O55076 | 298 | CDK2_CRIGR Cyclin-dependent kinase 2 OS=Crice... | 203 | 9e-17 | 86.3 | 33 | 51 | GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 532 | P92958 | 512 | KIN11_ARATH SNF1-related protein kinase catal... | 280 | 9e-17 | 88.6 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW. | 533 | P48025 | 629 | KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus... | 306 | 9e-17 | 89 | 26 | 46 | GO:0019815; C:B cell receptor complex; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032009; C:early phagosome; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:MGI.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IDA:MGI. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IMP:MGI.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0043366; P:beta selection; IGI:MGI.::GO:0071226; P:cellular response to molecule of fungal origin; IMP:UniProtKB.::GO:0042742; P:defense response to bacterium; IMP:UniProtKB.::GO:0007167; P:enzyme linked receptor protein signaling pathway; IDA:MGI.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:MGI.::GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0007159; P:leukocyte cell-cell adhesion; ISS:UniProtKB.::GO:0019370; P:leukotriene biosynthetic process; IMP:MGI.::GO:0001945; P:lymph vessel development; IMP:UniProtKB.::GO:0002281; P:macrophage activation involved in immune response; IMP:UniProtKB.::GO:0002283; P:neutrophil activation involved in immune response; IMP:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:UniProtKB.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IGI:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IGI:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IMP:MGI.::GO:0045780; P:positive regulation of bone resorption; IMP:UniProtKB.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:MGI.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IGI:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0045425; P:positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; IMP:MGI.::GO:0045401; P:positive regulation of interleukin-3 biosynthetic process; IMP:MGI.::GO:0043306; P:positive regulation of mast cell degranulation; IMP:MGI.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0090237; P:regulation of arachidonic acid secretion; IMP:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043313; P:regulation of neutrophil degranulation; IMP:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0032928; P:regulation of superoxide anion generation; IMP:UniProtKB.::GO:0002554; P:serotonin secretion by platelet; IMP:UniProtKB. | 534 | P43405 | 635 | KSYK_HUMAN Tyrosine-protein kinase SYK OS=Hom... | 306 | 9e-17 | 89 | 25 | 46 | GO:0005829; C:cytosol; IC:UniProtKB.::GO:0032009; C:early phagosome; ISS:UniProtKB.::GO:0042101; C:T cell receptor complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0071226; P:cellular response to molecule of fungal origin; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007159; P:leukocyte cell-cell adhesion; IDA:UniProtKB.::GO:0001945; P:lymph vessel development; ISS:UniProtKB.::GO:0002281; P:macrophage activation involved in immune response; ISS:UniProtKB.::GO:0002283; P:neutrophil activation involved in immune response; ISS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.::GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0090237; P:regulation of arachidonic acid secretion; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043313; P:regulation of neutrophil degranulation; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0032928; P:regulation of superoxide anion generation; ISS:UniProtKB.::GO:0002554; P:serotonin secretion by platelet; ISS:UniProtKB. | 535 | P0C865 | 806 | MK07_RAT Mitogen-activated protein kinase 7 O... | 253 | 1e-16 | 89.4 | 27 | 47 | GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:RGD. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 536 | Q90ZK6 | 504 | ACVR1_CHICK Activin receptor type-1 OS=Gallus... | 303 | 1e-16 | 88.6 | 28 | 43 | | | | | | | | | | | GO:0048185; F:activin binding; TAS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.::GO:0050431; F:transforming growth factor beta binding; IPI:AgBase.::GO:0005025; F:transforming growth factor beta receptor activity, type I; IDA:AgBase. | | | | | | | | | | GO:0060317; P:cardiac epithelial to mesenchymal transition; IMP:AgBase.::GO:0051216; P:cartilage development; IEP:AgBase.::GO:0042118; P:endothelial cell activation; IMP:AgBase.::GO:0035111; P:leg joint morphogenesis; IMP:AgBase.::GO:0035286; P:leg segmentation; IMP:AgBase.::GO:0001707; P:mesoderm formation; TAS:AgBase.::GO:0010694; P:positive regulation of alkaline phosphatase activity; IMP:AgBase.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:AgBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:AgBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:AgBase.::GO:0032330; P:regulation of chondrocyte differentiation; IGI:AgBase.::GO:0042325; P:regulation of phosphorylation; IPI:AgBase. | 537 | Q9LV48 | 652 | PERK1_ARATH Proline-rich receptor-like protei... | 194 | 1e-16 | 89 | 32 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009620; P:response to fungus; ISS:TAIR.::GO:0009611; P:response to wounding; ISS:TAIR. | 538 | A5PKJ4 | 781 | MK07_BOVIN Mitogen-activated protein kinase 7... | 253 | 1e-16 | 89.4 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 539 | Q55BA0 | 765 | Y9866_DICDI Probable serine/threonine-protein... | 238 | 1e-16 | 89.4 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 540 | Q769I5 | 1384 | MET_BOVIN Hepatocyte growth factor receptor O... | 280 | 1e-16 | 89.7 | 24 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 541 | Q9CAL2 | 646 | CRK3_ARATH Cysteine-rich receptor-like protei... | 216 | 1e-16 | 89 | 31 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | |
