| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q05688 | 640 | IGF1R_BOVIN Insulin-like growth factor 1 rece... | 302 | 4e-19 | 96.7 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0051389; P:inactivation of MAPKK activity; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB. | 272 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 294 | 5e-19 | 97.1 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 273 | P09560 | 638 | RAF1_XENLA RAF proto-oncogene serine/threonin... | 285 | 5e-19 | 96.3 | 29 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 274 | P00533 | 1210 | EGFR_HUMAN Epidermal growth factor receptor O... | 281 | 5e-19 | 97.1 | 26 | 48 | GO:0016323; C:basolateral plasma membrane; IDA:BHF-UCL.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; NAS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0070435; C:Shc-EGFR complex; ISS:BHF-UCL. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003690; F:double-stranded DNA binding; NAS:UniProtKB.::GO:0005006; F:epidermal growth factor-activated receptor activity; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004710; F:MAPK/ERK kinase kinase activity; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0043006; P:activation of phospholipase A2 activity by calcium-mediated signaling; TAS:UniProtKB.::GO:0007202; P:activation of phospholipase C activity; TAS:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0016337; P:cell-cell adhesion; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProtKB.::GO:0001503; P:ossification; NAS:UniProtKB.::GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0051205; P:protein insertion into membrane; TAS:UniProtKB.::GO:0050999; P:regulation of nitric-oxide synthase activity; IDA:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:UniProtKB.::GO:0006950; P:response to stress; NAS:UniProtKB.::GO:0070141; P:response to UV-A; IDA:BHF-UCL. | 275 | P43293 | 389 | NAK_ARATH Probable serine/threonine-protein k... | 331 | 6e-19 | 94 | 28 | 46 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 276 | P00535 | 604 | ERBB_AVIER Tyrosine-protein kinase transformi... | 281 | 6e-19 | 95.9 | 26 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 277 | Q8K0D0 | 523 | CDK17_MOUSE Cyclin-dependent kinase 17 OS=Mus... | 200 | 6e-19 | 95.5 | 32 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 278 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 293 | 6e-19 | 95.5 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 279 | Q55FT4 | 2247 | TSUA_DICDI Probable serine/threonine-protein ... | 196 | 7e-19 | 97.1 | 35 | 52 | GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 280 | O65405 | 683 | CRK28_ARATH Cysteine-rich receptor-like prote... | 231 | 7e-19 | 95.9 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 281 | B2MVY4 | 303 | CDK4_SHEEP Cyclin-dependent kinase 4 OS=Ovis ... | 234 | 7e-19 | 93.2 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 282 | Q32KY4 | 303 | CDK4_BOVIN Cyclin-dependent kinase 4 OS=Bos t... | 234 | 7e-19 | 93.2 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 283 | Q8RXC8 | 460 | RBK2_ARATH Receptor-like cytosolic serine/thr... | 250 | 7e-19 | 94.7 | 31 | 46 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 284 | P79432 | 303 | CDK4_PIG Cyclin-dependent kinase 4 OS=Sus scr... | 234 | 7e-19 | 92.8 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 285 | Q62413 | 1035 | EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus m... | 349 | 7e-19 | 96.7 | 28 | 43 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IEA:InterPro. | | | | | | | | | | | 286 | Q9DGD3 | 303 | CDK1_ORYLA Cyclin-dependent kinase 1 OS=Oryzi... | 205 | 7e-19 | 92.8 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 287 | F1NBT0 | 969 | STK10_CHICK Serine/threonine-protein kinase 1... | 201 | 7e-19 | 96.3 | 30 | 47 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 288 | P00531 | 380 | MIL_AVIMH Serine/threonine-protein kinase-tra... | 276 | 8e-19 | 93.6 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 289 | P12931 | 536 | SRC_HUMAN Proto-oncogene tyrosine-protein kin... | 288 | 8e-19 | 95.1 | 28 | 47 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 290 | O08815 | 1206 | SLK_RAT STE20-like serine/threonine-protein k... | 209 | 8e-19 | 96.7 | 31 | 48 | GO:0005737; C:cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 291 | Q3EDL4 | 472 | Y1154_ARATH Probable serine/threonine-protein... | 213 | 8e-19 | 94.7 | 31 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR. | 292 | Q1ZXD6 | 2800 | ROCO5_DICDI Probable serine/threonine-protein... | 279 | 9e-19 | 96.7 | 29 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 293 | Q9DGA2 | 303 | CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzi... | 205 | 9e-19 | 92.8 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 294 | P30530 | 894 | UFO_HUMAN Tyrosine-protein kinase receptor UF... | 322 | 1e-18 | 95.9 | 30 | 47 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0048469; P:cell maturation; IEP:UniProtKB.::GO:0035457; P:cellular response to interferon-alpha; IDA:UniProtKB.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.::GO:0097028; P:dendritic cell differentiation; IEP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:2000669; P:negative regulation of dendritic cell apoptotic process; IDA:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.::GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0032825; P:positive regulation of natural killer cell differentiation; IDA:UniProtKB. | 295 | Q9DG98 | 303 | CDK1_ORYLU Cyclin-dependent kinase 1 OS=Oryzi... | 205 | 1e-18 | 92.4 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 296 | O54988 | 1233 | SLK_MOUSE STE20-like serine/threonine-protein... | 209 | 1e-18 | 96.3 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 297 | Q9QY78 | 757 | IKKB_RAT Inhibitor of nuclear factor kappa-B ... | 226 | 1e-18 | 95.5 | 33 | 50 | GO:0008385; C:IkappaB kinase complex; IDA:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD. | 298 | Q01279 | 1210 | EGFR_MOUSE Epidermal growth factor receptor O... | 281 | 1e-18 | 95.9 | 26 | 48 | GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005006; F:epidermal growth factor-activated receptor activity; IDA:MGI.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0000902; P:cell morphogenesis; IGI:MGI.::GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0048546; P:digestive tract morphogenesis; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0060571; P:morphogenesis of an epithelial fold; IMP:MGI.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:MGI.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0007435; P:salivary gland morphogenesis; IMP:MGI. | 299 | P08103 | 524 | HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus ... | 275 | 1e-18 | 94.7 | 26 | 50 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IGI:MGI.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 300 | Q9PVZ4 | 1362 | INSR_XENLA Insulin receptor OS=Xenopus laevis... | 301 | 1e-18 | 95.9 | 26 | 47 | GO:0005887; C:integral to plasma membrane; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.::GO:0051425; F:PTB domain binding; IPI:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051290; P:protein heterotetramerization; IDA:UniProtKB. | 301 | P09769 | 529 | FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo... | 290 | 1e-18 | 94.7 | 27 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc. |
