| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q54JG7 | 485 | DST4_DICDI Serine/threonine-protein kinase ds... | 272 | 4e-20 | 99 | 30 | 49 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 212 | P41239 | 450 | CSK_CHICK Tyrosine-protein kinase CSK OS=Gall... | 272 | 4e-20 | 98.2 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 213 | P41242 | 505 | MATK_MOUSE Megakaryocyte-associated tyrosine-... | 261 | 4e-20 | 99 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 214 | Q6XHB2 | 1726 | ROCO4_DICDI Probable serine/threonine-protein... | 301 | 4e-20 | 100 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 215 | Q5UQG7 | 1651 | YR818_MIMIV Putative serine/threonine-protein... | 287 | 5e-20 | 100 | 27 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 216 | Q05438 | 502 | BMR1B_CHICK Bone morphogenetic protein recept... | 302 | 5e-20 | 99 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0051216; P:cartilage development; IEA:UniProtKB-KW. | 217 | Q5PXS1 | 509 | LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotu... | 285 | 5e-20 | 99 | 28 | 49 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 218 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 281 | 5e-20 | 99 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 219 | O00238 | 502 | BMR1B_HUMAN Bone morphogenetic protein recept... | 302 | 5e-20 | 98.6 | 29 | 45 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0043235; C:receptor complex; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:HGNC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IDA:HGNC.::GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; NAS:UniProtKB.::GO:0001502; P:cartilage condensation; NAS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0035108; P:limb morphogenesis; IMP:UniProtKB.::GO:0001550; P:ovarian cumulus expansion; ISS:UniProtKB.::GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL. | 220 | P41241 | 450 | CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ... | 273 | 5e-20 | 98.2 | 28 | 49 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC. | 221 | Q55A55 | 986 | Y9848_DICDI Probable serine/threonine-protein... | 220 | 5e-20 | 100 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 222 | P06213 | 1382 | INSR_HUMAN Insulin receptor OS=Homo sapiens (... | 297 | 5e-20 | 100 | 28 | 47 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005899; C:insulin receptor complex; IMP:BHF-UCL.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; IDA:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0031995; F:insulin-like growth factor II binding; IPI:BHF-UCL.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:BHF-UCL.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0051425; F:PTB domain binding; IPI:UniProtKB.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IDA:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:BHF-UCL.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.::GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; IMP:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IDA:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:BHF-UCL.::GO:0045821; P:positive regulation of glycolysis; IMP:BHF-UCL.::GO:0043410; P:positive regulation of MAPK cascade; IMP:BHF-UCL.::GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0060267; P:positive regulation of respiratory burst; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0051290; P:protein heterotetramerization; IDA:UniProtKB.::GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:BHF-UCL.::GO:0019087; P:transformation of host cell by virus; IMP:BHF-UCL. | 223 | Q5ZJK4 | 486 | STK4_CHICK Serine/threonine-protein kinase 4 ... | 202 | 6e-20 | 98.2 | 36 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 224 | Q95KR7 | 509 | LCK_SAISC Proto-oncogene tyrosine-protein kin... | 285 | 6e-20 | 98.6 | 28 | 49 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 225 | Q0VBZ0 | 450 | CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ... | 271 | 7e-20 | 97.8 | 28 | 49 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 226 | Q90344 | 987 | EPHB2_COTJA Ephrin type-B receptor 2 OS=Cotur... | 286 | 7e-20 | 99.8 | 29 | 48 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB. | 227 | P07948 | 512 | LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo... | 266 | 7e-20 | 98.2 | 26 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0070668; P:positive regulation of mast cell proliferation; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0070304; P:positive regulation of stress-activated protein kinase signaling cascade; IDA:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090025; P:regulation of monocyte chemotaxis; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 228 | Q924U5 | 570 | TESK2_RAT Dual specificity testis-specific pr... | 279 | 7e-20 | 98.6 | 30 | 49 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:UniProtKB. | 229 | P42685 | 505 | FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo... | 296 | 8e-20 | 98.2 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 230 | Q64261 | 326 | CDK6_MOUSE Cyclin-dependent kinase 6 OS=Mus m... | 228 | 8e-20 | 96.3 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:MGI.::GO:0060218; P:hemopoietic stem cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0033077; P:T cell differentiation in thymus; IMP:MGI. | 231 | Q6PA14 | 485 | STK4_XENLA Serine/threonine-protein kinase 4 ... | 269 | 9e-20 | 97.8 | 30 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 232 | P15208 | 1372 | INSR_MOUSE Insulin receptor OS=Mus musculus (... | 302 | 9e-20 | 99.8 | 28 | 47 | GO:0005901; C:caveola; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043559; F:insulin binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB.::GO:0051425; F:PTB domain binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IDA:MGI.::GO:0031017; P:exocrine pancreas development; IMP:MGI.::GO:0030238; P:male sex determination; IMP:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051290; P:protein heterotetramerization; ISS:UniProtKB. | 233 | Q00534 | 326 | CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo ... | 201 | 9e-20 | 95.9 | 34 | 53 | GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0001726; C:ruffle; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021542; P:dentate gyrus development; ISS:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IEP:BHF-UCL.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0021670; P:lateral ventricle development; ISS:UniProtKB.::GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB. | 234 | Q6NU21 | 1001 | TAO1A_XENLA Serine/threonine-protein kinase T... | 290 | 9e-20 | 99.4 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 235 | P57097 | 994 | MERTK_RAT Tyrosine-protein kinase Mer OS=Ratt... | 311 | 1e-19 | 99.4 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001750; C:photoreceptor outer segment; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:RGD. | | | | | | | | | | | 236 | Q10407 | 1116 | MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S... | 284 | 1e-19 | 99.4 | 30 | 46 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase. | 237 | P15127 | 1383 | INSR_RAT Insulin receptor OS=Rattus norvegicu... | 302 | 1e-19 | 99.4 | 28 | 47 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005768; C:endosome; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0045202; C:synapse; IDA:RGD. | | | | | | | | | | GO:0043423; F:3-phosphoinositide-dependent protein kinase binding; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043559; F:insulin binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IMP:RGD.::GO:0005009; F:insulin-activated receptor activity; IDA:RGD.::GO:0031405; F:lipoic acid binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IMP:RGD. | | | | | | | | | | GO:0045444; P:fat cell differentiation; IEP:RGD.::GO:0042593; P:glucose homeostasis; IDA:RGD.::GO:0010629; P:negative regulation of gene expression; IMP:RGD.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:RGD.::GO:0032410; P:negative regulation of transporter activity; IMP:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:RGD.::GO:0010560; P:positive regulation of glycoprotein biosynthetic process; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051290; P:protein heterotetramerization; IDA:RGD.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; IDA:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:BHF-UCL.::GO:0010042; P:response to manganese ion; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0034612; P:response to tumor necrosis factor; IMP:RGD.::GO:0033280; P:response to vitamin D; IEP:RGD. | 238 | Q91147 | 729 | FGFR2_NOTVI Fibroblast growth factor receptor... | 309 | 1e-19 | 98.6 | 26 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 239 | Q91727 | 319 | CDK4_XENLA Cyclin-dependent kinase 4 OS=Xenop... | 227 | 1e-19 | 95.5 | 35 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 240 | Q84TI6 | 470 | CDKE1_ARATH Cyclin-dependent kinase E-1 OS=Ar... | 220 | 1e-19 | 97.1 | 33 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW. | 241 | Q06418 | 890 | TYRO3_HUMAN Tyrosine-protein kinase receptor ... | 318 | 1e-19 | 98.6 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0005635; C:nuclear envelope; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; NAS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; ISS:UniProtKB.::GO:0021885; P:forebrain cell migration; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; ISS:UniProtKB.::GO:0070050; P:neuron homeostasis; ISS:UniProtKB.::GO:0042698; P:ovulation cycle; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; NAS:UniProtKB.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032940; P:secretion by cell; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. |
