rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O62829 | 382 | PPM1A_BOVIN Protein phosphatase 1A OS=Bos tau... | 172 | 0.11 | 37.7 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase. | 32 | P49443 | 382 | PPM1A_MOUSE Protein phosphatase 1A OS=Mus mus... | 172 | 0.17 | 37 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IDA:MGI. | 33 | Q7XU84 | 352 | P2C42_ORYSJ Probable protein phosphatase 2C 4... | 22 | 0.23 | 36.6 | 64 | 77 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 34 | P49596 | 356 | PP2C2_CAEEL Probable protein phosphatase 2C T... | 162 | 0.25 | 36.6 | 26 | 39 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 35 | Q67J17 | 422 | P2C69_ORYSJ Probable protein phosphatase 2C 6... | 91 | 0.28 | 36.6 | 29 | 47 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 36 | P20650 | 382 | PPM1A_RAT Protein phosphatase 1A OS=Rattus no... | 172 | 0.42 | 35.8 | 25 | 39 | GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB. | | | | | | | | | | | 37 | Q94H98 | 380 | P2C34_ORYSJ Probable protein phosphatase 2C 3... | 156 | 0.44 | 35.8 | 26 | 41 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 38 | Q5MFV5 | 380 | P2C34_ORYSI Probable protein phosphatase 2C 3... | 156 | 0.44 | 35.8 | 26 | 41 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 39 | P35813 | 382 | PPM1A_HUMAN Protein phosphatase 1A OS=Homo sa... | 172 | 0.45 | 35.8 | 25 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IDA:BHF-UCL. | 40 | P35814 | 382 | PPM1A_RABIT Protein phosphatase 1A OS=Oryctol... | 172 | 0.47 | 35.8 | 25 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase. | 41 | O81716 | 355 | P2C21_ARATH Probable protein phosphatase 2C 2... | 192 | 0.47 | 35.4 | 20 | 38 | GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR. | 42 | Q9LHJ9 | 385 | P2C38_ARATH Probable protein phosphatase 2C 3... | 64 | 0.48 | 35.4 | 33 | 59 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 43 | Q9FXE4 | 445 | P2C14_ARATH Probable protein phosphatase 2C 1... | 62 | 0.53 | 35.4 | 34 | 52 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 44 | Q84JD5 | 393 | P2C68_ARATH Probable protein phosphatase 2C 6... | 23 | 0.64 | 35.4 | 61 | 74 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 45 | Q6L5C4 | 491 | P2C52_ORYSJ Probable protein phosphatase 2C 5... | 191 | 0.64 | 35.4 | 23 | 40 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 46 | Q9LUU7 | 422 | P2C43_ARATH Probable protein phosphatase 2C 4... | 25 | 0.85 | 35 | 48 | 72 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 47 | O88483 | 538 | PDP1_RAT [Pyruvate dehydrogenase [acetyl-tran... | 233 | 1 | 34.7 | 20 | 39 | GO:0005759; C:mitochondrial matrix; TAS:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IDA:RGD.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD.::GO:0032403; F:protein complex binding; IMP:RGD. | | | | | | | | | | GO:0043085; P:positive regulation of catalytic activity; IC:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.] | 48 | Q7XCJ7 | 393 | P2C72_ORYSJ Probable protein phosphatase 2C 7... | 74 | 1.3 | 34.3 | 34 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 49 | Q9SZ53 | 357 | P2C60_ARATH Probable protein phosphatase 2C 6... | 22 | 1.8 | 33.9 | 55 | 77 | GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 50 | Q94AT1 | 420 | P2C76_ARATH Probable protein phosphatase 2C 7... | 190 | 2.2 | 33.5 | 22 | 38 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 51 | Q9SD12 | 379 | P2C46_ARATH Probable protein phosphatase 2C 4... | 55 | 2.5 | 33.5 | 36 | 55 | GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 52 | P39966 | 464 | PP2C2_YEAST Protein phosphatase 2C homolog 2 ... | 37 | 2.5 | 33.5 | 38 | 65 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; IGI:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD. | 53 | Q7XHN8 | 377 | P2C61_ORYSJ Probable protein phosphatase 2C 6... | 23 | 3.3 | 33.1 | 57 | 70 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 54 | Q5RA52 | 537 | PDP1_PONAB [Pyruvate dehydrogenase [acetyl-tr... | 234 | 3.7 | 33.1 | 20 | 38 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro.] | 55 | P35816 | 538 | PDP1_BOVIN [Pyruvate dehydrogenase [acetyl-tr... | 234 | 4.2 | 32.7 | 20 | 38 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; NAS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro.] | 56 | Q501F9 | 370 | P2C67_ARATH Probable protein phosphatase 2C 6... | 20 | 4.8 | 32.3 | 55 | 75 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 57 | A3A8W2 | 340 | P2C21_ORYSJ Probable protein phosphatase 2C 2... | 25 | 5 | 32.3 | 44 | 64 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 58 | Q9P0J1 | 537 | PDP1_HUMAN [Pyruvate dehydrogenase [acetyl-tr... | 234 | 5.2 | 32.3 | 20 | 38 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC. | | | | | | | | | | GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.] | 59 | P38089 | 393 | PP2C4_YEAST Protein phosphatase 2C homolog 4 ... | 74 | 5.2 | 32.3 | 32 | 46 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IDA:SGD. | 60 | Q6K1U4 | 521 | P2C16_ORYSJ Probable protein phosphatase 2C 1... | 22 | 5.4 | 32.3 | 50 | 73 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 61 | Q7XUC5 | 388 | P2C43_ORYSJ Probable protein phosphatase 2C 4... | 23 | 5.5 | 32.3 | 48 | 74 | GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. |