| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q5F415 | 679 | TBC23_CHICK TBC1 domain family member 23 OS=G... | 136 | 0.17 | 38.9 | 22 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 122 | Q54TA5 | 1016 | TBC5B_DICDI TBC1 domain family member 5 homol... | 110 | 0.21 | 38.9 | 23 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 123 | Q01705 | 2531 | NOTC1_MOUSE Neurogenic locus notch homolog pr... | 86 | 0.32 | 38.1 | 28 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0072044; P:collecting duct development; IEP:UniProtKB.::GO:0072017; P:distal tubule development; IEP:UniProtKB.::GO:0003160; P:endocardium morphogenesis; IEP:BHF-UCL.::GO:0072144; P:glomerular mesangial cell development; IEP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0060253; P:negative regulation of glial cell proliferation; IDA:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; IDA:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.::GO:2000974; P:negative regulation of pro-B cell differentiation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; IC:UniProtKB.::GO:0002051; P:osteoblast fate commitment; NAS:BHF-UCL.::GO:0048711; P:positive regulation of astrocyte differentiation; IDA:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:UniProtKB.::GO:0032495; P:response to muramyl dipeptide; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 124 | Q9HA65 | 648 | TBC17_HUMAN TBC1 domain family member 17 OS=H... | 184 | 0.32 | 38.1 | 22 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 125 | Q8K0F1 | 684 | TBC23_MOUSE TBC1 domain family member 23 OS=M... | 305 | 0.81 | 36.6 | 20 | 36 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 126 | P26448 | 306 | BUB2_YEAST Mitotic check point protein BUB2 O... | 187 | 1.1 | 35.8 | 22 | 37 | GO:0005816; C:spindle pole body; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031578; P:mitotic cell cycle spindle orientation checkpoint; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; TAS:SGD. | 127 | P21783 | 2524 | NOTCH_XENLA Neurogenic locus notch protein ho... | 65 | 2 | 35.8 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0050793; P:regulation of developmental process; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 128 | Q19546 | 1056 | WRN_CAEEL Probable Werner syndrome ATP-depend... | 130 | 2.9 | 35 | 27 | 41 | GO:0005694; C:chromosome; IDA:WormBase.::GO:0005654; C:nucleoplasm; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:WormBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase. | 129 | A0KIH3 | 169 | SEQA_AERHH Negative modulator of initiation o... | 90 | 5.3 | 33.1 | 33 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032297; P:negative regulation of DNA-dependent DNA replication initiation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 130 | Q008X6 | 6872 | R1AB_WBV24 Replicase polyprotein 1ab OS=White... | 286 | 9.3 | 33.5 | 23 | 39 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0032774; P:RNA biosynthetic process; IEA:UniProtKB-KW. |
