| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q16696 | 494 | CP2AD_HUMAN Cytochrome P450 2A13 OS=Homo sapi... | 537 | 3e-30 | 127 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 182 | P20813 | 491 | CP2B6_HUMAN Cytochrome P450 2B6 OS=Homo sapie... | 493 | 3e-30 | 127 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; NAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042180; P:cellular ketone metabolic process; IDA:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 183 | Q8CIM7 | 500 | CP2DQ_MOUSE Cytochrome P450 2D26 OS=Mus muscu... | 491 | 3e-30 | 127 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 184 | P33264 | 490 | CP2CR_MESAU Cytochrome P450 2C27 OS=Mesocrice... | 465 | 3e-30 | 127 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 185 | P33268 | 503 | CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas... | 518 | 3e-30 | 127 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 186 | P04800 | 504 | CP3A1_RAT Cytochrome P450 3A1 OS=Rattus norve... | 524 | 3e-30 | 127 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 187 | P05093 | 508 | CP17A_HUMAN Steroid 17-alpha-hydroxylase/17,2... | 498 | 5e-30 | 127 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 188 | Q8HYN1 | 508 | CP17A_PANTR Steroid 17-alpha-hydroxylase/17,2... | 497 | 7e-30 | 126 | 25 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 189 | Q91Z85 | 509 | CP17A_PERLE Steroid 17-alpha-hydroxylase/17,2... | 510 | 9e-30 | 126 | 25 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 190 | P20852 | 494 | CP2A5_MOUSE Cytochrome P450 2A5 OS=Mus muscul... | 548 | 1e-29 | 125 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0035634; P:response to stilbenoid; IEP:UniProtKB. | 191 | P08684 | 503 | CP3A4_HUMAN Cytochrome P450 3A4 OS=Homo sapie... | 496 | 1e-29 | 125 | 25 | 46 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0047638; F:albendazole monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0050591; F:quinine 3-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IDA:BHF-UCL.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 192 | Q29497 | 509 | CP17A_SHEEP Steroid 17-alpha-hydroxylase/17,2... | 515 | 1e-29 | 125 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 193 | Q6VVW9 | 501 | CP2R1_MOUSE Vitamin D 25-hydroxylase OS=Mus m... | 486 | 1e-29 | 125 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:MGI. | | | | | | | | | | GO:0042359; P:vitamin D metabolic process; IDA:MGI. | 194 | Q556M4 | 493 | C5082_DICDI Probable cytochrome P450 508A2 OS... | 521 | 1e-29 | 125 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 195 | Q9JMA7 | 504 | CP341_MOUSE Cytochrome P450 3A41 OS=Mus muscu... | 511 | 1e-29 | 125 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 196 | P00176 | 491 | CP2B1_RAT Cytochrome P450 2B1 OS=Rattus norve... | 486 | 1e-29 | 125 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010477; P:response to sulfur dioxide; IEP:RGD. | 197 | Q9VWR5 | 574 | CP306_DROME Cytochrome P450 306a1 OS=Drosophi... | 587 | 2e-29 | 126 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035302; F:ecdysteroid 25-hydroxylase activity; IDA:FlyBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0006697; P:ecdysone biosynthetic process; IDA:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase. | 198 | O81974 | 504 | C71D8_SOYBN Cytochrome P450 71D8 OS=Glycine m... | 509 | 2e-29 | 125 | 23 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 199 | Q9SWR5 | 521 | C93C1_SOYBN 2-hydroxyisoflavanone synthase OS... | 478 | 2e-29 | 125 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0033770; F:2-hydroxyisoflavanone synthase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009717; P:isoflavonoid biosynthetic process; IDA:UniProtKB. | 200 | O65012 | 553 | C78A4_PINRA Cytochrome P450 78A4 OS=Pinus rad... | 529 | 2e-29 | 125 | 25 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 201 | P05185 | 509 | CP17A_BOVIN Steroid 17-alpha-hydroxylase/17,2... | 523 | 3e-29 | 124 | 24 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 202 | O81972 | 522 | C82A2_SOYBN Cytochrome P450 82A2 OS=Glycine m... | 528 | 3e-29 | 124 | 24 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 203 | Q9GMC7 | 509 | CP17A_BISBI Steroid 17-alpha-hydroxylase/17,2... | 526 | 3e-29 | 124 | 24 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 204 | P51538 | 503 | CP3A9_RAT Cytochrome P450 3A9 OS=Rattus norve... | 515 | 3e-29 | 124 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; TAS:RGD. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 205 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 514 | 4e-29 | 124 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 206 | Q64583 | 495 | CP2BF_RAT Cytochrome P450 2B15 OS=Rattus norv... | 519 | 4e-29 | 124 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0008392; F:arachidonic acid epoxygenase activity; IDA:RGD.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:RGD. | 207 | P11509 | 494 | CP2A6_HUMAN Cytochrome P450 2A6 OS=Homo sapie... | 539 | 5e-29 | 124 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008389; F:coumarin 7-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0046226; P:coumarin catabolic process; IDA:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 208 | P00178 | 491 | CP2B4_RABIT Cytochrome P450 2B4 OS=Oryctolagu... | 517 | 5e-29 | 124 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 209 | Q50EK4 | 525 | C75A1_PINTA Cytochrome P450 750A1 OS=Pinus ta... | 509 | 5e-29 | 124 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 210 | Q42798 | 509 | C93A1_SOYBN Cytochrome P450 93A1 OS=Glycine m... | 535 | 8e-29 | 123 | 23 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 211 | O23976 | 490 | C76B1_HELTU 7-ethoxycoumarin O-deethylase OS=... | 511 | 8e-29 | 123 | 25 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |
