rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6CLS0 | 433 | MCA1_KLULA Metacaspase-1 OS=1267 / NRRL Y-114... | 391 | 5e-113 | 347 | 50 | 62 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 32 | Q75B43 | 452 | MCA1_ASHGO Metacaspase-1 OS=Y-1056) (Yeast) (... | 470 | 6e-113 | 347 | 44 | 57 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 33 | A1D611 | 411 | MCA1B_NEOFI Metacaspase-1B OS=181) (Aspergill... | 303 | 1e-111 | 343 | 57 | 73 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 34 | A2QU58 | 438 | MCA1B_ASPNC Metacaspase-1B OS=Aspergillus nig... | 326 | 9e-110 | 338 | 54 | 71 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 35 | Q08601 | 432 | MCA1_YEAST Metacaspase-1 OS=Saccharomyces cer... | 378 | 8e-105 | 325 | 50 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:SGD.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:SGD. | 36 | A6ZP43 | 432 | MCA1_YEAS7 Metacaspase-1 OS=Saccharomyces cer... | 378 | 8e-105 | 325 | 50 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 37 | Q6FPX9 | 392 | MCA1_CANGA Metacaspase-1 OS=NRRL Y-65) (Yeast... | 335 | 4e-103 | 320 | 51 | 65 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 38 | Q7XJE6 | 367 | MCA1_ARATH Metacaspase-1 OS=Arabidopsis thali... | 279 | 6e-48 | 174 | 37 | 55 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IDA:TAIR. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0043068; P:positive regulation of programmed cell death; IDA:TAIR.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | Q7XJE5 | 418 | MCA2_ARATH Metacaspase-2 OS=Arabidopsis thali... | 283 | 2e-47 | 174 | 35 | 53 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0043069; P:negative regulation of programmed cell death; IGI:TAIR.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 40 | Q9FMG1 | 362 | MCA3_ARATH Metacaspase-3 OS=Arabidopsis thali... | 160 | 4e-41 | 155 | 44 | 69 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 41 | O64517 | 418 | MCA4_ARATH Metacaspase-4 OS=Arabidopsis thali... | 87 | 0.077 | 38.9 | 36 | 56 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0016540; P:protein autoprocessing; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 42 | O64519 | 368 | MCA6_ARATH Metacaspase-6 OS=Arabidopsis thali... | 153 | 6e-23 | 103 | 41 | 56 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | Q6XPT5 | 403 | MCA7_ARATH Metacaspase-7 OS=Arabidopsis thali... | 87 | 0.0008 | 45.4 | 37 | 54 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 44 | Q9FYE1 | 325 | MCA9_ARATH Metacaspase-9 OS=Arabidopsis thali... | 320 | 2e-21 | 98.6 | 29 | 43 | GO:0048046; C:apoplast; IDA:TAIR. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 45 | O64518 | 410 | MCA5_ARATH Metacaspase-5 OS=Arabidopsis thali... | 107 | 0.006 | 42.7 | 36 | 53 | GO:0009507; C:chloroplast; IDA:TAIR. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IDA:TAIR. | | | | | | | | | | GO:0043068; P:positive regulation of programmed cell death; IDA:TAIR.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 46 | Q9SA41 | 381 | MCA8_ARATH Metacaspase-8 OS=Arabidopsis thali... | 151 | 7e-20 | 94.4 | 37 | 53 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IDA:TAIR. | | | | | | | | | | GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IMP:TAIR.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042542; P:response to hydrogen peroxide; IMP:TAIR.::GO:0010225; P:response to UV-C; IEP:TAIR. | 47 | Q9P219 | 2028 | DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu... | 112 | 0.003 | 43.9 | 34 | 38 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 48 | Q9DDT5 | 1084 | SPT5H_DANRE Transcription elongation factor S... | 233 | 0.068 | 39.7 | 25 | 36 | GO:0005634; C:nucleus; IDA:ZFIN. | | | | | | | | | | | | | | | | | | | | GO:0030097; P:hemopoiesis; IMP:ZFIN.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:ZFIN.::GO:0001764; P:neuron migration; IMP:ZFIN.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:ZFIN.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:ZFIN. | 49 | O00267 | 1087 | SPT5H_HUMAN Transcription elongation factor S... | 268 | 0.12 | 38.9 | 26 | 36 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0032785; P:negative regulation of transcription elongation, DNA-dependent; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0010033; P:response to organic substance; TAS:UniProtKB.::GO:0045090; P:retroviral genome replication; NAS:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB. | 50 | Q5R405 | 1083 | SPT5H_PONAB Transcription elongation factor S... | 262 | 0.19 | 38.1 | 26 | 35 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | O55201 | 1082 | SPT5H_MOUSE Transcription elongation factor S... | 259 | 0.23 | 37.7 | 26 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI. | | | | | | | | | | GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:InterPro. | 52 | Q5ZI08 | 1079 | SPT5H_CHICK Transcription elongation factor S... | 268 | 0.47 | 37 | 26 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | A6NC98 | 1476 | CC88B_HUMAN Coiled-coil domain-containing pro... | 171 | 0.48 | 37 | 27 | 36 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro. | 54 | A2CG49 | 2964 | KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ... | 53 | 0.85 | 36.2 | 36 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 55 | Q5VST9 | 7968 | OBSCN_HUMAN Obscurin OS=Homo sapiens (Human).... | 121 | 0.91 | 36.2 | 30 | 31 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; ISS:BHF-UCL.::GO:0030018; C:Z disc; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 56 | Q6FJG8 | 888 | BRO1_CANGA Vacuolar protein-sorting protein B... | 151 | 1.8 | 35 | 29 | 36 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 57 | O88277 | 4351 | FAT2_RAT Protocadherin Fat 2 OS=Rattus norveg... | 127 | 4.6 | 33.9 | 28 | 39 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB. | 58 | P16952 | 1500 | SSP5_STRGN Agglutinin receptor OS=Streptococc... | 113 | 6 | 33.5 | 26 | 32 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009274; C:peptidoglycan-based cell wall; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0044406; P:adhesion to host; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:InterPro. | 59 | Q9NQT8 | 1826 | KI13B_HUMAN Kinesin-like protein KIF13B OS=Ho... | 112 | 6.1 | 33.1 | 28 | 38 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007018; P:microtubule-based movement; TAS:UniProtKB.::GO:0006605; P:protein targeting; TAS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB. | 60 | Q7Z7A1 | 2325 | CNTRL_HUMAN Centriolin OS=Homo sapiens (Human... | 68 | 6.3 | 33.1 | 37 | 38 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. | 61 | B1AT66 | 607 | MOT7_MOUSE Monocarboxylate transporter 7 OS=M... | 104 | 6.6 | 33.1 | 32 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | |