rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O69462 | 282 | Y1669_MYCLE Uncharacterized oxidoreductase ML... | 264 | 1e-46 | 163 | 34 | 57 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 32 | B8ZS00 | 282 | Y1669_MYCLB Uncharacterized oxidoreductase ML... | 264 | 1e-46 | 163 | 34 | 57 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 290 | 1e-46 | 164 | 34 | 53 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 34 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 290 | 3e-46 | 163 | 34 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 35 | Q8VCX1 | 325 | AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen... | 290 | 6e-46 | 162 | 33 | 55 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 36 | Q55FL3 | 321 | ALRC_DICDI Aldose reductase C OS=Dictyosteliu... | 286 | 7e-46 | 162 | 33 | 58 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; ISS:dictyBase. | 37 | P50578 | 325 | AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=... | 285 | 4e-45 | 160 | 31 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 38 | Q6IMN8 | 297 | ALRA_DICDI Aldose reductase A OS=Dictyosteliu... | 274 | 5e-45 | 159 | 32 | 56 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase. | 39 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 284 | 5e-45 | 159 | 31 | 56 | | | | | | | | | | | | | | | | | | | | | | 40 | Q54NZ7 | 311 | ALRB_DICDI Aldose reductase B OS=Dictyosteliu... | 285 | 8e-45 | 159 | 32 | 58 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase. | | | | | | | | | | | 41 | Q6W8P9 | 323 | AK1CO_HORSE Aldo-keto reductase family 1 memb... | 287 | 8e-45 | 159 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 42 | P52898 | 323 | DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos... | 288 | 1e-44 | 159 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 43 | A0QV10 | 275 | Y2408_MYCS2 Uncharacterized oxidoreductase MS... | 264 | 2e-44 | 157 | 33 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | Q9JII6 | 325 | AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O... | 284 | 3e-44 | 157 | 31 | 56 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI. | | | | | | | | | | GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI. | 45 | Q5R5D5 | 325 | AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O... | 284 | 3e-44 | 157 | 31 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 46 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 285 | 5e-44 | 157 | 30 | 55 | | | | | | | | | | | | | | | | | | | | | | 47 | Q9TV64 | 326 | AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen... | 291 | 5e-44 | 157 | 32 | 53 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 48 | P51857 | 326 | AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen... | 291 | 6e-44 | 157 | 32 | 53 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB. | 49 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 284 | 9e-44 | 156 | 31 | 55 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 50 | Q8ZM06 | 275 | DKGA_SALTY 2,5-diketo-D-gluconic acid reducta... | 263 | 1e-43 | 155 | 35 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 51 | P58744 | 275 | DKGA_SALTI Putative 2,5-diketo-D-gluconic aci... | 263 | 1e-43 | 155 | 35 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 52 | P17516 | 323 | AK1C4_HUMAN Aldo-keto reductase family 1 memb... | 287 | 3e-43 | 155 | 33 | 51 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB. | 53 | P31210 | 326 | AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenas... | 292 | 1e-42 | 153 | 32 | 54 | | | | | | | | | | | GO:0047568; F:3-oxo-5-beta-steroid 4-dehydrogenase activity; IDA:MGI.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 54 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 286 | 2e-42 | 153 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 55 | P70694 | 323 | DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ... | 293 | 2e-42 | 152 | 32 | 52 | | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IDA:MGI. | 56 | P82125 | 301 | AKCL2_PIG 1,5-anhydro-D-fructose reductase OS... | 280 | 2e-42 | 152 | 32 | 53 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 57 | O60218 | 316 | AK1BA_HUMAN Aldo-keto reductase family 1 memb... | 277 | 4e-42 | 152 | 30 | 53 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc. | 58 | P06632 | 278 | DKGA_CORSC 2,5-diketo-D-gluconic acid reducta... | 255 | 5e-42 | 150 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 59 | P15339 | 277 | DKGB_CORSS 2,5-diketo-D-gluconic acid reducta... | 261 | 1e-41 | 149 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 60 | Q95JH5 | 323 | AK1C4_MACFA Aldo-keto reductase family 1 memb... | 290 | 1e-41 | 150 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 61 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 290 | 3e-41 | 149 | 32 | 53 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. |