| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | O35942 | 443 | NEK2_MOUSE Serine/threonine-protein kinase Ne... | 328 | 2e-22 | 103 | 25 | 41 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:MGI.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0043392; P:negative regulation of DNA binding; IDA:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB. | 602 | O55092 | 1231 | SLK_CAVPO STE20-like serine/threonine-protein... | 247 | 2e-22 | 104 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 603 | B3DL84 | 946 | PLK4_XENTR Serine/threonine-protein kinase PL... | 249 | 2e-22 | 104 | 28 | 47 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 604 | Q9Y2U5 | 619 | M3K2_HUMAN Mitogen-activated protein kinase k... | 298 | 2e-22 | 104 | 27 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 605 | Q9CEF5 | 627 | PKNB_LACLA Probable serine/threonine-protein ... | 309 | 2e-22 | 104 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 606 | Q8XJL8 | 685 | PKN2_CLOPE Probable serine/threonine-protein ... | 243 | 2e-22 | 104 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 607 | P25390 | 1331 | SSK22_YEAST Serine/threonine-protein kinase S... | 277 | 2e-22 | 104 | 28 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD. | 608 | Q0IHQ8 | 951 | STK10_XENTR Serine/threonine-protein kinase 1... | 256 | 2e-22 | 104 | 29 | 46 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 609 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 246 | 2e-22 | 104 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 610 | O08875 | 433 | DCLK1_RAT Serine/threonine-protein kinase DCL... | 300 | 2e-22 | 102 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 611 | Q2TA25 | 602 | PLK1_BOVIN Serine/threonine-protein kinase PL... | 244 | 3e-22 | 103 | 29 | 45 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB. | 612 | O97143 | 769 | PLK4_DROME Serine/threonine-protein kinase PL... | 315 | 3e-22 | 103 | 26 | 43 | GO:0005814; C:centriole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase. | 613 | B3NE99 | 766 | PLK4_DROER Serine/threonine-protein kinase PL... | 315 | 3e-22 | 103 | 26 | 43 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 614 | Q42479 | 529 | CDPK3_ARATH Calcium-dependent protein kinase ... | 301 | 3e-22 | 103 | 29 | 44 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0010359; P:regulation of anion channel activity; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR. | 615 | Q2HJF7 | 488 | KCC2D_BOVIN Calcium/calmodulin-dependent prot... | 309 | 3e-22 | 103 | 26 | 41 | GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB. | 616 | Q9Z265 | 546 | CHK2_MOUSE Serine/threonine-protein kinase Ch... | 250 | 3e-22 | 103 | 28 | 47 | GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042176; P:regulation of protein catabolic process; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:MGI.::GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 617 | Q9DG02 | 475 | KCC2D_XENLA Calcium/calmodulin-dependent prot... | 309 | 3e-22 | 102 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 618 | Q5E9L6 | 487 | STK4_BOVIN Serine/threonine-protein kinase 4 ... | 306 | 3e-22 | 102 | 24 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 619 | O42844 | 504 | KCC2_SCHPO Calcium/calmodulin-dependent prote... | 307 | 3e-22 | 103 | 25 | 46 | GO:0030428; C:cell septum; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; TAS:PomBase.::GO:0005516; F:calmodulin binding; TAS:PomBase.::GO:0004683; F:calmodulin-dependent protein kinase activity; IMP:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase. | 620 | Q6PAD2 | 944 | PLK4_XENLA Serine/threonine-protein kinase PL... | 249 | 3e-22 | 103 | 28 | 47 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 621 | Q9C958 | 361 | SRK2B_ARATH Serine/threonine-protein kinase S... | 312 | 3e-22 | 101 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009651; P:response to salt stress; IDA:TAIR. | 622 | O15075 | 740 | DCLK1_HUMAN Serine/threonine-protein kinase D... | 301 | 3e-22 | 103 | 28 | 44 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; TAS:ProtInc. | | | | | | | | | | GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009615; P:response to virus; IEP:UniProtKB. | 623 | B4PDM5 | 766 | PLK4_DROYA Serine/threonine-protein kinase PL... | 315 | 3e-22 | 103 | 26 | 43 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 624 | P43292 | 353 | SRK2G_ARATH Serine/threonine-protein kinase S... | 317 | 3e-22 | 101 | 26 | 43 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009651; P:response to salt stress; IDA:TAIR. | 625 | B4QK53 | 769 | PLK4_DROSI Serine/threonine-protein kinase PL... | 315 | 3e-22 | 103 | 26 | 43 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 626 | B3NKK1 | 745 | DCLK_DROER Serine/threonine-protein kinase GG... | 295 | 3e-22 | 103 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 627 | O94547 | 580 | SRK1_SCHPO Serine/threonine-protein kinase sr... | 384 | 3e-22 | 103 | 25 | 44 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:PomBase.::GO:0040020; P:regulation of meiosis; IMP:PomBase.::GO:0007088; P:regulation of mitosis; IPI:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase. | 628 | Q8C0X8 | 640 | SMKX_MOUSE Sperm motility kinase X OS=Mus mus... | 288 | 3e-22 | 103 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 629 | O96017 | 543 | CHK2_HUMAN Serine/threonine-protein kinase Ch... | 250 | 4e-22 | 103 | 29 | 47 | GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB.::GO:0090399; P:replicative senescence; NAS:BHF-UCL.::GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 630 | Q75L42 | 454 | CIPKH_ORYSJ CBL-interacting protein kinase 17... | 235 | 4e-22 | 102 | 32 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 631 | B0WAU8 | 761 | PLK4_CULQU Serine/threonine-protein kinase PL... | 306 | 4e-22 | 103 | 25 | 42 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | |
