rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q76I79 | 1042 | SSH1_MOUSE Protein phosphatase Slingshot homo... | 184 | 0.00000002 | 62 | 27 | 43 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 32 | Q13202 | 625 | DUS8_HUMAN Dual specificity protein phosphata... | 187 | 0.00000002 | 61.6 | 25 | 41 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 33 | Q8WYL5 | 1049 | SSH1_HUMAN Protein phosphatase Slingshot homo... | 187 | 0.00000002 | 61.6 | 27 | 43 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0000902; P:cell morphogenesis; IMP:UniProtKB.::GO:0071318; P:cellular response to ATP; IDA:MGI.::GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0032268; P:regulation of cellular protein metabolic process; IDA:MGI.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 34 | O09112 | 663 | DUS8_MOUSE Dual specificity protein phosphata... | 187 | 0.00000002 | 61.2 | 25 | 41 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 35 | Q9Y6W6 | 482 | DUS10_HUMAN Dual specificity protein phosphat... | 183 | 0.00000002 | 60.8 | 28 | 44 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome. | 36 | Q9ESS0 | 483 | DUS10_MOUSE Dual specificity protein phosphat... | 76 | 0.00000003 | 60.8 | 39 | 58 | GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046329; P:negative regulation of JNK cascade; IMP:MGI.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:MGI.::GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IMP:MGI.::GO:0002819; P:regulation of adaptive immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 37 | Q9JLY7 | 198 | DUS14_MOUSE Dual specificity protein phosphat... | 208 | 0.00000003 | 58.2 | 25 | 38 | GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 38 | Q6IVY4 | 691 | SSH_XENLA Protein phosphatase Slingshot homol... | 184 | 0.0000004 | 57.4 | 24 | 40 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 39 | O95147 | 198 | DUS14_HUMAN Dual specificity protein phosphat... | 209 | 0.0000004 | 54.7 | 28 | 41 | | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 40 | Q17QM8 | 198 | DUS14_BOVIN Dual specificity protein phosphat... | 209 | 0.0000004 | 54.3 | 28 | 41 | | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 41 | Q556Y8 | 476 | DUSPR_DICDI Probable rhodanese domain-contain... | 186 | 0.000001 | 55.1 | 24 | 42 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 42 | Q8TE77 | 659 | SSH3_HUMAN Protein phosphatase Slingshot homo... | 211 | 0.000003 | 54.3 | 26 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 43 | P0C599 | 210 | DUPD1_TAKRU Dual specificity phosphatase DUPD... | 161 | 0.000006 | 51.2 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 44 | Q54Y32 | 856 | MPL3_DICDI MAP kinase phosphatase with leucin... | 187 | 0.000008 | 53.1 | 28 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 45 | Q8WTR2 | 217 | DUS19_HUMAN Dual specificity protein phosphat... | 180 | 0.00001 | 50.8 | 25 | 38 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0008579; F:JUN kinase phosphatase activity; IBA:RefGenome.::GO:0005078; F:MAP-kinase scaffold activity; ISS:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; ISS:BHF-UCL.::GO:0030295; F:protein kinase activator activity; ISS:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:BHF-UCL. | 46 | Q9VVW5 | 411 | DUSK3_DROME Dual specificity protein phosphat... | 191 | 0.00001 | 52 | 24 | 43 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0042127; P:regulation of cell proliferation; IGI:FlyBase. | 47 | Q9M8K7 | 167 | DUS1B_ARATH Dual specificity protein phosphat... | 93 | 0.00001 | 49.7 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.::GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.::GO:0010193; P:response to ozone; IMP:TAIR. | 48 | Q8K4T5 | 220 | DUS19_MOUSE Dual specificity protein phosphat... | 195 | 0.00002 | 50.1 | 25 | 39 | | | | | | | | | | | GO:0005078; F:MAP-kinase scaffold activity; IDA:BHF-UCL.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.::GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0046329; P:negative regulation of JNK cascade; IDA:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL. | 49 | Q5U593 | 223 | STYXB_XENLA Serine/threonine/tyrosine-interac... | 80 | 0.00003 | 49.7 | 34 | 54 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 50 | Q60969 | 223 | STYX_MOUSE Serine/threonine/tyrosine-interact... | 105 | 0.00003 | 49.7 | 33 | 49 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 51 | Q5RD73 | 185 | DUS3_PONAB Dual specificity protein phosphata... | 192 | 0.00003 | 48.9 | 27 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 52 | P51452 | 185 | DUS3_HUMAN Dual specificity protein phosphata... | 192 | 0.00003 | 48.9 | 27 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 53 | Q8K330 | 649 | SSH3_MOUSE Protein phosphatase Slingshot homo... | 207 | 0.00003 | 51.2 | 25 | 38 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 54 | Q4V7N3 | 223 | STYXA_XENLA Serine/threonine/tyrosine-interac... | 80 | 0.00004 | 49.3 | 34 | 54 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 55 | Q54T76 | 394 | DUSP4_DICDI Probable dual specificity protein... | 96 | 0.00004 | 50.1 | 34 | 46 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 56 | Q5RDP3 | 223 | STYX_PONAB Serine/threonine/tyrosine-interact... | 80 | 0.00006 | 48.5 | 35 | 54 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 57 | Q9NRW4 | 184 | DUS22_HUMAN Dual specificity protein phosphat... | 186 | 0.00006 | 47.8 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 58 | Q8WUJ0 | 223 | STYX_HUMAN Serine/threonine/tyrosine-interact... | 80 | 0.00006 | 48.5 | 35 | 54 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007283; P:spermatogenesis; IBA:RefGenome. | 59 | Q9D7X3 | 185 | DUS3_MOUSE Dual specificity protein phosphata... | 184 | 0.00007 | 47.8 | 26 | 46 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome. | 60 | Q5XIS1 | 652 | SSH3_RAT Protein phosphatase Slingshot homolo... | 210 | 0.00008 | 49.7 | 26 | 40 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 61 | Q5XHB2 | 209 | DUS22_XENTR Dual specificity protein phosphat... | 186 | 0.0001 | 47.4 | 24 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. |