| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P20107 | 442 | ZRC1_YEAST Zinc/cadmium resistance protein OS... | 420 | 2e-99 | 311 | 44 | 60 | GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005385; F:zinc ion transmembrane transporter activity; IMP:SGD. | | | | | | | | | | GO:0006882; P:cellular zinc ion homeostasis; IMP:SGD.::GO:0006824; P:cobalt ion transport; NAS:SGD.::GO:0006749; P:glutathione metabolic process; NAS:SGD.::GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW. | 2 | O13918 | 387 | ZHF1_SCHPO Zinc homeostasis factor 1 OS=Schiz... | 416 | 3e-96 | 301 | 43 | 58 | GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005385; F:zinc ion transmembrane transporter activity; IMP:PomBase. | | | | | | | | | | GO:0006876; P:cellular cadmium ion homeostasis; IMP:PomBase.::GO:0006877; P:cellular cobalt ion homeostasis; IMP:PomBase.::GO:0006882; P:cellular zinc ion homeostasis; IMP:PomBase. | 3 | P32798 | 439 | COT1_YEAST Cobalt uptake protein COT1 OS=Sacc... | 430 | 8e-89 | 284 | 39 | 54 | GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015087; F:cobalt ion transmembrane transporter activity; IMP:SGD.::GO:0005385; F:zinc ion transmembrane transporter activity; IGI:SGD. | | | | | | | | | | GO:0006882; P:cellular zinc ion homeostasis; IMP:SGD. | 4 | Q3UVU3 | 470 | ZNT10_MOUSE Zinc transporter 10 OS=Mus muscul... | 453 | 4e-70 | 236 | 32 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 5 | Q60738 | 503 | ZNT1_MOUSE Zinc transporter 1 OS=Mus musculus... | 485 | 1e-66 | 227 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019855; F:calcium channel inhibitor activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IDA:BHF-UCL.::GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0090281; P:negative regulation of calcium ion import; IDA:BHF-UCL.::GO:0071584; P:negative regulation of zinc ion import; IDA:BHF-UCL. | 6 | Q6XR72 | 485 | ZNT10_HUMAN Zinc transporter 10 OS=Homo sapie... | 463 | 6e-65 | 222 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 7 | Q62720 | 507 | ZNT1_RAT Zinc transporter 1 OS=Rattus norvegi... | 473 | 3e-64 | 221 | 32 | 47 | GO:0016021; C:integral to membrane; IDA:RGD.::GO:0030315; C:T-tubule; IDA:BHF-UCL. | | | | | | | | | | GO:0019855; F:calcium channel inhibitor activity; IMP:BHF-UCL.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:MGI. | | | | | | | | | | GO:0070574; P:cadmium ion transmembrane transport; IMP:BHF-UCL.::GO:0070509; P:calcium ion import; IMP:BHF-UCL.::GO:0071585; P:detoxification of cadmium ion; IMP:BHF-UCL.::GO:0046929; P:negative regulation of neurotransmitter secretion; IMP:BHF-UCL. | 8 | Q9Y6M5 | 507 | ZNT1_HUMAN Zinc transporter 1 OS=Homo sapiens... | 469 | 1e-63 | 219 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030315; C:T-tubule; ISS:BHF-UCL. | | | | | | | | | | GO:0019855; F:calcium channel inhibitor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0070574; P:cadmium ion transmembrane transport; ISS:BHF-UCL.::GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.::GO:0006882; P:cellular zinc ion homeostasis; ISS:BHF-UCL.::GO:0090281; P:negative regulation of calcium ion import; ISS:BHF-UCL.::GO:0046929; P:negative regulation of neurotransmitter secretion; ISS:BHF-UCL.::GO:0071584; P:negative regulation of zinc ion import; ISS:BHF-UCL. | 9 | Q4R6K2 | 505 | ZNT1_MACFA Zinc transporter 1 OS=Macaca fasci... | 469 | 7e-63 | 218 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 10 | Q95QW4 | 561 | CDF1_CAEEL Cation diffusion facilitator famil... | 444 | 9e-43 | 163 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0071294; P:cellular response to zinc ion; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046579; P:positive regulation of Ras protein signal transduction; IGI:WormBase.::GO:0040026; P:positive regulation of vulval development; IGI:WormBase.::GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 11 | Q54T06 | 573 | Y8206_DICDI Probable zinc transporter protein... | 130 | 7e-20 | 95.9 | 39 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005385; F:zinc ion transmembrane transporter activity; ISS:dictyBase. | | | | | | | | | | GO:0006882; P:cellular zinc ion homeostasis; ISS:dictyBase. | 12 | Q9HGQ3 | 732 | CIS4_SCHPO Probable zinc transporter cis4 OS=... | 383 | 5e-19 | 93.6 | 24 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0000139; C:Golgi membrane; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0005385; F:zinc ion transmembrane transporter activity; IMP:PomBase. | | | | | | | | | | GO:0006882; P:cellular zinc ion homeostasis; IMP:PomBase.::GO:0016192; P:vesicle-mediated transport; IMP:PomBase. | 13 | Q8H329 | 316 | MTP8_ORYSJ Metal tolerance protein 8 OS=Oryza... | 129 | 0.000000000000007 | 78.6 | 36 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | | 14 | Q54F34 | 770 | Y1141_DICDI Probable zinc transporter protein... | 116 | 0.0000000006 | 65.1 | 34 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005385; F:zinc ion transmembrane transporter activity; ISS:dictyBase. | | | | | | | | | | | 15 | Q8BGG0 | 367 | ZNT8_MOUSE Zinc transporter 8 OS=Mus musculus... | 143 | 0.000000008 | 60.8 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL. | | | | | | | | | | GO:0030073; P:insulin secretion; IMP:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IMP:BHF-UCL. | 16 | Q52KD7 | 386 | ZNT7A_XENLA Zinc transporter 7-A OS=Xenopus l... | 160 | 0.00000001 | 60.1 | 23 | 46 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 17 | Q8ZGY6 | 312 | ZITB_YERPE Zinc transporter zitB OS=Yersinia ... | 153 | 2e-16 | 83.2 | 32 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 18 | Q66D85 | 312 | ZITB_YERPS Zinc transporter zitB OS=Yersinia ... | 153 | 3e-17 | 85.9 | 33 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 19 | Q08E25 | 388 | ZNT3_BOVIN Zinc transporter 3 OS=Bos taurus (... | 149 | 0.000000004 | 62 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 20 | Q6NRI1 | 390 | ZNT7B_XENLA Zinc transporter 7-B OS=Xenopus l... | 157 | 0.000000005 | 61.6 | 24 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 21 | Q6P3N9 | 390 | ZNT7_XENTR Zinc transporter 7 OS=Xenopus trop... | 157 | 0.000000005 | 61.6 | 24 | 48 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 22 | Q6QIX3 | 388 | ZNT3_RAT Zinc transporter 3 OS=Rattus norvegi... | 137 | 0.0000003 | 55.8 | 28 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 23 | P13512 | 316 | CZCD_RALME Cobalt-zinc-cadmium resistance pro... | 129 | 0.031 | 40 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.::GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 24 | P94178 | 316 | CZCD_ALCSC Cation efflux system protein CzcD ... | 129 | 0.035 | 39.7 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 25 | Q5R617 | 388 | ZNT3_PONAB Zinc transporter 3 OS=Pongo abelii... | 145 | 0.000000004 | 62 | 29 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. | 26 | Q99726 | 388 | ZNT3_HUMAN Zinc transporter 3 OS=Homo sapiens... | 145 | 0.000000002 | 63.2 | 30 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005770; C:late endosome; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015633; F:zinc transporting ATPase activity; TAS:ProtInc. | | | | | | | | | | GO:0061088; P:regulation of sequestering of zinc ion; IDA:BHF-UCL. | 27 | Q8R4H9 | 761 | ZNT5_MOUSE Zinc transporter 5 OS=Mus musculus... | 149 | 0.000000000001 | 73.6 | 31 | 52 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 28 | Q8TAD4 | 765 | ZNT5_HUMAN Zinc transporter 5 OS=Homo sapiens... | 143 | 0.000000000005 | 71.6 | 30 | 52 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:UniProtKB.::GO:0005624; C:membrane fraction; NAS:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0030667; C:secretory granule membrane; TAS:Reactome. | | | | | | | | | | GO:0008270; F:zinc ion binding; NAS:UniProtKB.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0006882; P:cellular zinc ion homeostasis; IDA:UniProtKB.::GO:0006824; P:cobalt ion transport; IDA:MGI.::GO:0010155; P:regulation of proton transport; NAS:UniProtKB.::GO:0010043; P:response to zinc ion; IDA:UniProtKB. | 29 | Q8IWU4 | 369 | ZNT8_HUMAN Zinc transporter 8 OS=Homo sapiens... | 143 | 0.0000000008 | 63.9 | 31 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030667; C:secretory granule membrane; TAS:Reactome.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IC:BHF-UCL.::GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL. | | | | | | | | | | GO:0030073; P:insulin secretion; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0061088; P:regulation of sequestering of zinc ion; ISS:BHF-UCL.::GO:0060627; P:regulation of vesicle-mediated transport; ISS:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IMP:BHF-UCL.::GO:0032119; P:sequestering of zinc ion; IDA:BHF-UCL. | 30 | Q9SI03 | 300 | MTP12_ARATH Metal tolerance protein 12 OS=Ara... | 144 | 0.00000000001 | 68.6 | 31 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | | 31 | Q5MNV6 | 378 | ZNT7_CHICK Zinc transporter 7 OS=Gallus gallu... | 150 | 0.00000004 | 58.5 | 27 | 49 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. |
