| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5F4C0 | 235 | HVCN1_CHICK Voltage-gated hydrogen channel 1 ... | 129 | 0.032 | 38.1 | 28 | 47 | GO:0016021; C:integral to membrane; ISS:HGNC. | | | | | | | | | | GO:0030171; F:voltage-gated proton channel activity; ISS:HGNC. | | | | | | | | | | GO:0009268; P:response to pH; ISS:HGNC.::GO:0010043; P:response to zinc ion; ISS:HGNC. | 2 | Q91ZR5 | 686 | CTSR1_MOUSE Cation channel sperm-associated p... | 50 | 1.3 | 33.9 | 28 | 58 | GO:0036128; C:CatSper complex; IDA:UniProtKB.::GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0020017; C:flagellar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IMP:MGI. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001539; P:ciliary or flagellar motility; IMP:MGI.::GO:0007342; P:fusion of sperm to egg plasma membrane; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 3 | P56698 | 2326 | CAC1B_DISOM Probable voltage-dependent N-type... | 117 | 1.8 | 33.5 | 26 | 43 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 4 | P19838 | 968 | NFKB1_HUMAN Nuclear factor NF-kappa-B p105 su... | 57 | 2 | 33.1 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0032269; P:negative regulation of cellular protein metabolic process; IC:BHF-UCL.::GO:0032375; P:negative regulation of cholesterol transport; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.::GO:0010884; P:positive regulation of lipid storage; IC:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 5 | Q6F3J0 | 972 | NFKB1_CANFA Nuclear factor NF-kappa-B p105 su... | 62 | 2.6 | 32.7 | 27 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | P25799 | 971 | NFKB1_MOUSE Nuclear factor NF-kappa-B p105 su... | 57 | 3.1 | 32.7 | 28 | 49 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048535; P:lymph node development; TAS:MGI.::GO:0001818; P:negative regulation of cytokine production; IMP:BHF-UCL.::GO:0045083; P:negative regulation of interleukin-12 biosynthetic process; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q04861 | 983 | NFKB1_CHICK Nuclear factor NF-kappa-B p105 su... | 57 | 3.4 | 32.3 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | P17972 | 498 | KCNAW_DROME Potassium voltage-gated channel p... | 57 | 5.3 | 31.6 | 32 | 54 | GO:0008076; C:voltage-gated potassium channel complex; TAS:FlyBase. | | | | | | | | | | GO:0005249; F:voltage-gated potassium channel activity; TAS:FlyBase. | | | | | | | | | | GO:0030431; P:sleep; IMP:FlyBase. |
