| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
841 | Q04736 | 541 | YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ... | 270 | 0.0001 | 48.1 | 22 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0015758; P:glucose transport; IDA:MGI. | 842 | Q2QSL4 | 327 | CDKF2_ORYSJ Putative cyclin-dependent kinase ... | 224 | 0.0001 | 47.8 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 843 | O35280 | 476 | CHK1_MOUSE Serine/threonine-protein kinase Ch... | 245 | 0.0001 | 48.1 | 25 | 44 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005657; C:replication fork; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:MGI.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; IDA:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:UniProtKB. | 844 | Q91821 | 651 | MELK_XENLA Maternal embryonic leucine zipper ... | 153 | 0.0001 | 48.1 | 23 | 50 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 845 | Q8SR90 | 309 | Y8H9_ENCCU Probable cell division protein kin... | 228 | 0.0001 | 47.8 | 25 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 846 | Q7X996 | 443 | CIPK2_ORYSJ CBL-interacting protein kinase 2 ... | 243 | 0.0001 | 48.1 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 847 | P19454 | 339 | CSK22_YEAST Casein kinase II subunit alpha' O... | 159 | 0.0001 | 47.8 | 24 | 47 | GO:0005956; C:protein kinase CK2 complex; IDA:SGD.::GO:0034456; C:UTP-C complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0001300; P:chronological cell aging; IMP:SGD.::GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IDA:SGD. | 848 | P07313 | 608 | MYLK2_RABIT Myosin light chain kinase 2, skel... | 108 | 0.0001 | 48.1 | 28 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:BHF-UCL.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0032971; P:regulation of muscle filament sliding; IC:BHF-UCL. | 849 | Q9VXE5 | 639 | PAKM_DROME Serine/threonine-protein kinase PA... | 212 | 0.0001 | 48.1 | 26 | 42 | GO:0005913; C:cell-cell adherens junction; IDA:FlyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:FlyBase.::GO:0045315; P:positive regulation of compound eye photoreceptor development; IMP:UniProtKB. | 850 | Q9Y463 | 629 | DYR1B_HUMAN Dual specificity tyrosine-phospho... | 189 | 0.0001 | 48.1 | 28 | 47 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 851 | Q4P0K0 | 990 | ATG1_USTMA Serine/threonine-protein kinase AT... | 270 | 0.0001 | 48.5 | 21 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 852 | Q54BC9 | 915 | DYRK2_DICDI Probable serine/threonine-protein... | 217 | 0.0001 | 48.5 | 22 | 43 | GO:0005737; C:cytoplasm; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 853 | P20689 | 610 | MYLK2_RAT Myosin light chain kinase 2, skelet... | 108 | 0.0001 | 48.1 | 28 | 53 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0032027; F:myosin light chain binding; IMP:RGD.::GO:0004687; F:myosin light chain kinase activity; IDA:RGD. | | | | | | | | | | GO:0018105; P:peptidyl-serine phosphorylation; TAS:RGD.::GO:0051272; P:positive regulation of cellular component movement; IMP:RGD.::GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; IMP:RGD.::GO:0051726; P:regulation of cell cycle; IMP:RGD.::GO:0043408; P:regulation of MAPK cascade; IMP:RGD.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0048489; P:synaptic vesicle transport; IMP:RGD.::GO:0006833; P:water transport; IMP:RGD. | 854 | P65732 | 589 | PKNJ_MYCTU Probable serine/threonine-protein ... | 214 | 0.0001 | 48.1 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:MTBBASE. | 855 | P65733 | 589 | PKNJ_MYCBO Probable serine/threonine-protein ... | 214 | 0.0001 | 48.1 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 856 | P39745 | 444 | SUR1_CAEEL Mitogen-activated protein kinase m... | 156 | 0.0001 | 47.8 | 27 | 47 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0007265; P:Ras protein signal transduction; IGI:WormBase.::GO:0040025; P:vulval development; IMP:UniProtKB. | 857 | Q75Q66 | 357 | HOG1_GLOLA Mitogen-activated protein kinase H... | 205 | 0.0001 | 47.8 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 858 | P32485 | 435 | HOG1_YEAST Mitogen-activated protein kinase H... | 168 | 0.0001 | 47.8 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0006972; P:hyperosmotic response; IMP:SGD.::GO:0046020; P:negative regulation of transcription from RNA polymerase II promoter by pheromones; IEP:SGD.::GO:0007231; P:osmosensory signaling pathway; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0046685; P:response to arsenic-containing substance; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 859 | Q3SWY6 | 426 | STK25_BOVIN Serine/threonine-protein kinase 2... | 213 | 0.0001 | 47.8 | 23 | 41 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 860 | P34908 | 807 | BRAF_COTJA Serine/threonine-protein kinase B-... | 223 | 0.0001 | 48.1 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 861 | Q9Z188 | 629 | DYR1B_MOUSE Dual specificity tyrosine-phospho... | 189 | 0.0001 | 48.1 | 28 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007520; P:myoblast fusion; IMP:MGI. | 862 | P05132 | 351 | KAPCA_MOUSE cAMP-dependent protein kinase cat... | 194 | 0.0001 | 47.8 | 28 | 40 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0071374; P:cellular response to parathyroid hormone stimulus; IMP:MGI.::GO:0001707; P:mesoderm formation; IGI:MGI.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0048240; P:sperm capacitation; IDA:UniProtKB. | 863 | Q6BVA0 | 412 | IPL1_DEBHA Spindle assembly checkpoint kinase... | 243 | 0.0001 | 47.8 | 21 | 43 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 864 | P18266 | 420 | GSK3B_RAT Glycogen synthase kinase-3 beta OS=... | 166 | 0.0001 | 47.8 | 27 | 44 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IDA:RGD.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD. | 865 | Q9WV60 | 420 | GSK3B_MOUSE Glycogen synthase kinase-3 beta O... | 166 | 0.0001 | 47.8 | 27 | 44 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB. | 866 | Q5JLQ9 | 476 | CIPKU_ORYSJ CBL-interacting protein kinase 30... | 221 | 0.0001 | 47.8 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 867 | Q05655 | 676 | KPCD_HUMAN Protein kinase C delta type OS=Hom... | 212 | 0.0001 | 48.1 | 27 | 40 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; TAS:BHF-UCL.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0090398; P:cellular senescence; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032091; P:negative regulation of protein binding; TAS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042119; P:neutrophil activation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000304; P:positive regulation of ceramide biosynthetic process; IMP:BHF-UCL.::GO:2000753; P:positive regulation of glucosylceramide catabolic process; IMP:BHF-UCL.::GO:1900163; P:positive regulation of phospholipid scramblase activity; IMP:UniProtKB.::GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.::GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.::GO:2000755; P:positive regulation of sphingomyelin catabolic process; IMP:BHF-UCL.::GO:0032930; P:positive regulation of superoxide anion generation; IMP:UniProtKB.::GO:0050821; P:protein stabilization; NAS:UniProtKB.::GO:0010469; P:regulation of receptor activity; TAS:BHF-UCL.::GO:0023021; P:termination of signal transduction; IMP:BHF-UCL. | 868 | P0C431 | 357 | HOG1_GIBZE Mitogen-activated protein kinase H... | 205 | 0.0001 | 47.8 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 869 | Q8NEV4 | 1616 | MYO3A_HUMAN Myosin-IIIa OS=Homo sapiens (Huma... | 162 | 0.0001 | 48.5 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030898; F:actin-dependent ATPase activity; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0060002; F:plus-end directed microfilament motor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 870 | Q8N5S9 | 505 | KKCC1_HUMAN Calcium/calmodulin-dependent prot... | 141 | 0.0001 | 47.8 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007268; P:synaptic transmission; TAS:Reactome. | 871 | Q6ZQ29 | 1240 | TAOK2_MOUSE Serine/threonine-protein kinase T... | 147 | 0.0001 | 48.1 | 25 | 44 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB. |
