| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | O65438 | 499 | C71AR_ARATH Cytochrome P450 71A27 OS=Arabidop... | 204 | 0.000000000000002 | 80.1 | 27 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 452 | P10612 | 520 | CP11A_PIG Cholesterol side-chain cleavage enz... | 162 | 0.000000000000002 | 80.1 | 32 | 48 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 453 | Q1ZXL2 | 490 | C518B_DICDI Probable cytochrome P450 518B1 OS... | 189 | 0.000000000000002 | 79.7 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 454 | O15528 | 508 | CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydro... | 166 | 0.000000000000003 | 79.7 | 32 | 49 | GO:0005741; C:mitochondrial outer membrane; TAS:Reactome. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0030282; P:bone mineralization; IEP:BHF-UCL.::GO:0055074; P:calcium ion homeostasis; IMP:BHF-UCL.::GO:0006816; P:calcium ion transport; ISS:BHF-UCL.::GO:0046697; P:decidualization; IEP:BHF-UCL.::GO:0070314; P:G1 to G0 transition; IMP:BHF-UCL.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:BHF-UCL.::GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IEP:BHF-UCL.::GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IEP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IEP:BHF-UCL.::GO:0033280; P:response to vitamin D; IEP:BHF-UCL.::GO:0042368; P:vitamin D biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 455 | Q2XV99 | 521 | CP11A_MACFA Cholesterol side-chain cleavage e... | 162 | 0.000000000000003 | 79.3 | 33 | 48 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 456 | Q93VK5 | 595 | LUT5_ARATH Protein LUTEIN DEFICIENT 5, chloro... | 203 | 0.000000000000004 | 79.7 | 33 | 47 | GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0010291; F:carotene beta-ring hydroxylase activity; IMP:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016117; P:carotenoid biosynthetic process; IMP:TAIR. | 457 | Q93ZB2 | 509 | KO1_ARATH Ent-kaurene oxidase, chloroplastic ... | 179 | 0.000000000000004 | 79.3 | 32 | 46 | GO:0009707; C:chloroplast outer membrane; IDA:TAIR.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IMP:TAIR.::GO:0009740; P:gibberellic acid mediated signaling pathway; TAS:TAIR.::GO:0009686; P:gibberellin biosynthetic process; IDA:TAIR. | 458 | P36423 | 533 | THAS_MOUSE Thromboxane-A synthase OS=Mus musc... | 194 | 0.000000000000004 | 79.3 | 32 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0004796; F:thromboxane-A synthase activity; IMP:MGI. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 459 | Q86A22 | 494 | C515A_DICDI Probable cytochrome P450 515A1 OS... | 286 | 0.000000000000004 | 79.3 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 460 | Q27698 | 516 | CP6D1_MUSDO Cytochrome P450 6d1 OS=Musca dome... | 169 | 0.000000000000004 | 79.3 | 30 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 461 | P46194 | 503 | CP19A_BOVIN Cytochrome P450 19A1 OS=Bos tauru... | 247 | 0.000000000000005 | 79 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 462 | Q69FB6 | 503 | CP19A_LAGAC Cytochrome P450 19A1 OS=Lagenorhy... | 248 | 0.000000000000005 | 79 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 463 | Q1PS23 | 495 | AMO_ARTAN Amorpha-4,11-diene C-12 oxidase OS=... | 164 | 0.000000000000005 | 79 | 32 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 464 | O46051 | 507 | C4D14_DROME Probable cytochrome P450 4d14 OS=... | 167 | 0.000000000000006 | 78.6 | 34 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 465 | P24464 | 508 | CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv... | 176 | 0.000000000000006 | 78.6 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 466 | Q5QQX7 | 503 | CP19A_CANFA Cytochrome P450 19A1 OS=Canis fam... | 246 | 0.000000000000008 | 78.6 | 27 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 467 | Q9VE00 | 536 | C12A4_DROME Probable cytochrome P450 12a4, mi... | 191 | 0.000000000000008 | 78.2 | 33 | 50 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0017085; P:response to insecticide; IMP:FlyBase. | 468 | Q9LTM2 | 499 | C71BL_ARATH Cytochrome P450 71B21 OS=Arabidop... | 197 | 0.000000000000009 | 78.2 | 31 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 469 | P24462 | 503 | CP3A7_HUMAN Cytochrome P450 3A7 OS=Homo sapie... | 161 | 0.000000000000009 | 78.2 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 470 | Q9GJX5 | 504 | CP4AL_PIG Taurochenodeoxycholic 6 alpha-hydro... | 176 | 0.00000000000001 | 78.2 | 29 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC. | | | | | | | | | | | 471 | Q98T91 | 502 | C340_ORYLA Cytochrome P450 3A40 OS=Oryzias la... | 196 | 0.00000000000001 | 78.2 | 28 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 472 | P20817 | 507 | CP4AE_RAT Cytochrome P450 4A14 OS=Rattus norv... | 176 | 0.00000000000001 | 77.8 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IMP:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IMP:RGD.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IMP:RGD.::GO:0046456; P:icosanoid biosynthetic process; IMP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0043651; P:linoleic acid metabolic process; IDA:RGD. | 473 | P79153 | 520 | CP11A_CAPHI Cholesterol side-chain cleavage e... | 165 | 0.00000000000001 | 77.4 | 33 | 47 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 474 | Q5RCN6 | 525 | CP4V2_PONAB Cytochrome P450 4V2 OS=Pongo abel... | 171 | 0.00000000000002 | 77.4 | 36 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0010430; P:fatty acid omega-oxidation; ISS:UniProtKB. | 475 | P29981 | 511 | CP4C1_BLADI Cytochrome P450 4C1 OS=Blaberus d... | 194 | 0.00000000000002 | 77.4 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 476 | Q5TCH4 | 519 | CP4AM_HUMAN Cytochrome P450 4A22 OS=Homo sapi... | 176 | 0.00000000000002 | 77.4 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 477 | Q91WL5 | 508 | CP4CA_MOUSE Cytochrome P450 4A12A OS=Mus musc... | 176 | 0.00000000000002 | 77.4 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:MGI.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. | 478 | P51871 | 537 | CP4F6_RAT Cytochrome P450 4F6 OS=Rattus norve... | 187 | 0.00000000000002 | 77.4 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD. | 479 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 176 | 0.00000000000002 | 77.4 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 480 | P58045 | 497 | C71AE_ARATH Cytochrome P450 71A14 OS=Arabidop... | 253 | 0.00000000000002 | 77.4 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 481 | P00189 | 520 | CP11A_BOVIN Cholesterol side-chain cleavage e... | 165 | 0.00000000000002 | 77.4 | 33 | 47 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042359; P:vitamin D metabolic process; IDA:UniProtKB. |
