rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q6IVY4 | 691 | SSH_XENLA Protein phosphatase Slingshot homol... | 141 | 3e-19 | 89.4 | 38 | 53 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 2 | Q63340 | 280 | DUS7_RAT Dual specificity protein phosphatase... | 162 | 4e-18 | 83.6 | 33 | 54 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | | 3 | Q9D700 | 211 | DUS26_MOUSE Dual specificity protein phosphat... | 139 | 4e-18 | 82.8 | 35 | 54 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 4 | Q9ZR37 | 198 | DUS1_ARATH Dual specificity protein phosphata... | 137 | 4e-18 | 82.4 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 5 | O13632 | 330 | PVH1_SCHPO Tyrosine-protein phosphatase yvh1 ... | 141 | 7e-18 | 82.8 | 36 | 54 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:PomBase.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000027; P:ribosomal large subunit assembly; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 6 | Q5FVI9 | 211 | DUS26_RAT Dual specificity protein phosphatas... | 139 | 1e-17 | 81.3 | 35 | 53 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 7 | Q9DBB1 | 381 | DUS6_MOUSE Dual specificity protein phosphata... | 162 | 1e-17 | 82.8 | 35 | 52 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IMP:MGI. | 8 | Q64346 | 381 | DUS6_RAT Dual specificity protein phosphatase... | 162 | 2e-17 | 82.8 | 35 | 52 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 9 | Q16828 | 381 | DUS6_HUMAN Dual specificity protein phosphata... | 162 | 2e-17 | 82.4 | 35 | 52 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 10 | Q2KJ36 | 381 | DUS6_BOVIN Dual specificity protein phosphata... | 162 | 2e-17 | 82.4 | 35 | 52 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome. | 11 | Q9BV47 | 211 | DUS26_HUMAN Dual specificity protein phosphat... | 171 | 2e-17 | 80.9 | 32 | 47 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 12 | Q17QJ3 | 211 | DUS26_BOVIN Dual specificity protein phosphat... | 171 | 3e-17 | 80.5 | 32 | 46 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 13 | Q91Z46 | 422 | DUS7_MOUSE Dual specificity protein phosphata... | 162 | 3e-17 | 82.4 | 33 | 54 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 14 | Q9QYJ7 | 198 | DUS13_MOUSE Dual specificity protein phosphat... | 141 | 3e-17 | 80.1 | 37 | 54 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | | 15 | Q16829 | 419 | DUS7_HUMAN Dual specificity protein phosphata... | 162 | 3e-17 | 82.4 | 33 | 54 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 16 | Q5R6H6 | 211 | DUS26_PONAB Dual specificity protein phosphat... | 139 | 4e-17 | 79.7 | 35 | 53 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 17 | Q9D7X3 | 185 | DUS3_MOUSE Dual specificity protein phosphata... | 149 | 1e-16 | 77.8 | 33 | 51 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome. | 18 | Q8K330 | 649 | SSH3_MOUSE Protein phosphatase Slingshot homo... | 142 | 2e-16 | 81.3 | 34 | 51 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 19 | Q9UII6 | 198 | DUS13_HUMAN Dual specificity protein phosphat... | 141 | 3e-16 | 77.4 | 36 | 52 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0007126; P:meiosis; TAS:ProtInc.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 20 | Q556Y8 | 476 | DUSPR_DICDI Probable rhodanese domain-contain... | 144 | 4e-16 | 79.3 | 37 | 51 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 21 | Q55E39 | 212 | DUSP1_DICDI Probable dual specificity protein... | 142 | 6e-16 | 76.6 | 34 | 52 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 22 | Q8R4V2 | 235 | DUS15_MOUSE Dual specificity protein phosphat... | 144 | 7e-16 | 76.3 | 34 | 50 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 23 | Q5XIS1 | 652 | SSH3_RAT Protein phosphatase Slingshot homolo... | 142 | 0.000000000000001 | 78.6 | 34 | 51 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 24 | Q9M8K7 | 167 | DUS1B_ARATH Dual specificity protein phosphat... | 147 | 0.000000000000001 | 75.1 | 33 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.::GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.::GO:0010193; P:response to ozone; IMP:TAIR. | 25 | Q8BK84 | 215 | DUPD1_MOUSE Dual specificity phosphatase DUPD... | 142 | 0.000000000000002 | 74.7 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 26 | Q6B8I0 | 188 | MDSP_MOUSE Dual specificity protein phosphata... | 139 | 0.000000000000004 | 73.9 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | | 27 | Q1LWL2 | 208 | DS22A_DANRE Dual specificity protein phosphat... | 141 | 0.000000000000004 | 73.9 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 28 | Q5RD73 | 185 | DUS3_PONAB Dual specificity protein phosphata... | 149 | 0.000000000000004 | 73.9 | 32 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 29 | P51452 | 185 | DUS3_HUMAN Dual specificity protein phosphata... | 149 | 0.000000000000004 | 73.9 | 32 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 30 | O55737 | 142 | 123R_IIV6 Putative tyrosine phosphatase 123R ... | 145 | 0.000000000000004 | 73.2 | 30 | 53 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 31 | P0C594 | 220 | DUPD1_PANTR Dual specificity phosphatase DUPD... | 142 | 0.000000000000005 | 73.9 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | |