rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9D099 | 267 | ACER3_MOUSE Alkaline ceramidase 3 OS=Mus musc... | 242 | 3e-47 | 165 | 38 | 56 | | | | | | | | | | | | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro. | 2 | Q9NUN7 | 267 | ACER3_HUMAN Alkaline ceramidase 3 OS=Homo sap... | 242 | 5e-47 | 164 | 38 | 56 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB. | | | | | | | | | | GO:0070774; F:phytoceramidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0071602; P:phytosphingosine biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB. | 3 | Q02896 | 317 | YDC1_YEAST Alkaline ceramidase YDC1 OS=Saccha... | 271 | 2e-37 | 140 | 31 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071633; F:dihydroceramidase activity; IDA:SGD. | | | | | | | | | | GO:0046514; P:ceramide catabolic process; IMP:SGD. | 4 | P38298 | 316 | YPC1_YEAST Alkaline ceramidase YPC1 OS=Saccha... | 272 | 4e-36 | 136 | 33 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070774; F:phytoceramidase activity; IMP:SGD.::GO:0050291; F:sphingosine N-acyltransferase activity; IMP:SGD. | | | | | | | | | | GO:0046514; P:ceramide catabolic process; IMP:SGD. | 5 | Q6TMJ1 | 288 | DCD3A_DICDI Putative alkaline ceramidase dcd3... | 308 | 6e-26 | 108 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; ISS:dictyBase. | | | | | | | | | | GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase. | 6 | Q55DQ0 | 285 | DCD3B_DICDI Putative alkaline ceramidase dcd3... | 297 | 3e-17 | 82.8 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; ISS:dictyBase. | | | | | | | | | | GO:0046514; P:ceramide catabolic process; ISS:dictyBase.::GO:0006669; P:sphinganine-1-phosphate biosynthetic process; ISS:dictyBase. | 7 | Q5QJU3 | 275 | ACER2_HUMAN Alkaline ceramidase 2 OS=Homo sap... | 247 | 0.000000008 | 58.9 | 25 | 39 | GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB. | | | | | | | | | | GO:0017040; F:ceramidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro.::GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0090285; P:negative regulation of protein glycosylation in Golgi; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:UniProtKB.::GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB. | 8 | Q9VIP7 | 283 | ACASE_DROME Alkaline ceramidase OS=Drosophila... | 243 | 0.000000009 | 58.9 | 26 | 43 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:FlyBase.::GO:0046514; P:ceramide catabolic process; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB. | 9 | Q8VD53 | 275 | ACER2_MOUSE Alkaline ceramidase 2 OS=Mus musc... | 247 | 0.00000009 | 55.8 | 24 | 38 | | | | | | | | | | | GO:0017040; F:ceramidase activity; IEA:EC. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro. | 10 | Q8TDN7 | 264 | ACER1_HUMAN Alkaline ceramidase 1 OS=Homo sap... | 273 | 0.000002 | 51.6 | 22 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; IEA:EC. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 11 | O45145 | 272 | ACASE_CAEEL Alkaline ceramidase OS=Caenorhabd... | 253 | 0.000003 | 51.2 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; IEA:EC. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro. | 12 | Q60WT2 | 272 | ACASE_CAEBR Alkaline ceramidase OS=Caenorhabd... | 259 | 0.000005 | 50.8 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; IEA:EC. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro. | 13 | Q8R4X1 | 273 | ACER1_MOUSE Alkaline ceramidase 1 OS=Mus musc... | 93 | 0.00003 | 48.5 | 31 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; IDA:MGI. | | | | | | | | | | GO:0046514; P:ceramide catabolic process; IDA:MGI.::GO:0019216; P:regulation of lipid metabolic process; IDA:MGI. | 14 | Q568I2 | 266 | ACER1_DANRE Alkaline ceramidase 1 OS=Danio re... | 97 | 0.00008 | 47 | 28 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017040; F:ceramidase activity; IEA:EC. | | | | | | | | | | GO:0006672; P:ceramide metabolic process; IEA:InterPro. | 15 | Q9ZCH1 | 317 | FABH_RICPR 3-oxoacyl-[acyl-carrier-protein] s... | 139 | 0.15 | 37 | 28 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 16 | Q68VX7 | 317 | FABH_RICTY 3-oxoacyl-[acyl-carrier-protein] s... | 139 | 0.31 | 35.8 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] |