| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P37120 | 513 | C75A2_SOLME Flavonoid 3',5'-hydroxylase OS=So... | 459 | 6e-35 | 140 | 26 | 47 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 32 | P08682 | 493 | CP2E1_RABIT Cytochrome P450 2E1 OS=Oryctolagu... | 488 | 8e-35 | 140 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 33 | P11715 | 507 | CP17A_RAT Steroid 17-alpha-hydroxylase/17,20 ... | 462 | 1e-34 | 139 | 28 | 46 | GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IDA:RGD. | | | | | | | | | | GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0006702; P:androgen biosynthetic process; TAS:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0030728; P:ovulation; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IMP:RGD.::GO:0010034; P:response to acetate; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0017085; P:response to insecticide; IEP:RGD.::GO:0010212; P:response to ionizing radiation; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD. | 34 | Q5RBQ1 | 516 | CP1A2_PONAB Cytochrome P450 1A2 OS=Pongo abel... | 466 | 1e-34 | 139 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 35 | P10632 | 490 | CP2C8_HUMAN Cytochrome P450 2C8 OS=Homo sapie... | 468 | 2e-34 | 139 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0006082; P:organic acid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 36 | Q6VVW9 | 501 | CP2R1_MOUSE Vitamin D 25-hydroxylase OS=Mus m... | 476 | 3e-34 | 138 | 29 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:MGI. | | | | | | | | | | GO:0042359; P:vitamin D metabolic process; IDA:MGI. | 37 | P00184 | 524 | CP1A1_MOUSE Cytochrome P450 1A1 OS=Mus muscul... | 468 | 5e-34 | 137 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009308; P:amine metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI. | 38 | P00180 | 490 | CP2C1_RABIT Cytochrome P450 2C1 OS=Oryctolagu... | 463 | 6e-34 | 137 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 39 | P33262 | 490 | CP2CK_MACFA Cytochrome P450 2C20 OS=Macaca fa... | 476 | 7e-34 | 137 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 40 | P70085 | 517 | CP17A_ORYLA Steroid 17-alpha-hydroxylase/17,2... | 448 | 8e-34 | 137 | 25 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 41 | O18963 | 495 | CP2E1_BOVIN Cytochrome P450 2E1 OS=Bos taurus... | 489 | 8e-34 | 137 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 42 | P00182 | 489 | CP2C3_RABIT Cytochrome P450 2C3 OS=Oryctolagu... | 484 | 1e-33 | 136 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 43 | Q00557 | 524 | CP1A1_MESAU Cytochrome P450 1A1 OS=Mesocricet... | 526 | 1e-33 | 137 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 44 | P48419 | 508 | C75A3_PETHY Flavonoid 3',5'-hydroxylase 2 OS=... | 489 | 1e-33 | 136 | 25 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 45 | O77809 | 516 | CP1A2_MACFA Cytochrome P450 1A2 OS=Macaca fas... | 464 | 1e-33 | 136 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 46 | P05181 | 493 | CP2E1_HUMAN Cytochrome P450 2E1 OS=Homo sapie... | 478 | 2e-33 | 135 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 47 | Q9D816 | 490 | CP255_MOUSE Cytochrome P450 2C55 OS=Mus muscu... | 470 | 2e-33 | 135 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 48 | Q29473 | 500 | CP2DF_CANFA Cytochrome P450 2D15 OS=Canis fam... | 439 | 2e-33 | 135 | 28 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 49 | P00186 | 513 | CP1A2_MOUSE Cytochrome P450 1A2 OS=Mus muscul... | 466 | 4e-33 | 135 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | GO:0045333; P:cellular respiration; IMP:MGI.::GO:0071276; P:cellular response to cadmium ion; IDA:MGI.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0006778; P:porphyrin-containing compound metabolic process; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI. | 50 | Q9CX98 | 530 | CP2U1_MOUSE Cytochrome P450 2U1 OS=Mus muscul... | 475 | 4e-33 | 135 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 51 | P17666 | 490 | CP2CE_RABIT Cytochrome P450 2C14 OS=Oryctolag... | 487 | 5e-33 | 134 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 52 | Q6GUQ4 | 493 | CP2E1_MACMU Cytochrome P450 2E1 OS=Macaca mul... | 487 | 6e-33 | 134 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 53 | P24453 | 513 | CP1A2_MESAU Cytochrome P450 1A2 OS=Mesocricet... | 463 | 6e-33 | 134 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 54 | Q6VVX0 | 501 | CP2R1_HUMAN Vitamin D 25-hydroxylase OS=Homo ... | 454 | 1e-32 | 133 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042359; P:vitamin D metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 55 | Q4H4C3 | 516 | CP1A2_MACFU Cytochrome P450 1A2 OS=Macaca fus... | 464 | 1e-32 | 133 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 56 | P48418 | 506 | C75A1_PETHY Flavonoid 3',5'-hydroxylase 1 OS=... | 445 | 2e-32 | 133 | 24 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 57 | P70687 | 511 | CP17A_MESAU Steroid 17-alpha-hydroxylase/17,2... | 458 | 2e-32 | 133 | 27 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 58 | Q9MZY0 | 494 | CP2E1_CANFA Cytochrome P450 2E1 OS=Canis fami... | 498 | 2e-32 | 132 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 59 | P51581 | 493 | CP2E1_MESAU Cytochrome P450 2E1 OS=Mesocricet... | 493 | 2e-32 | 132 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 60 | O04790 | 510 | C75A7_EUSER Flavonoid 3',5'-hydroxylase OS=gr... | 491 | 3e-32 | 132 | 24 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 61 | Q92116 | 521 | CP1A1_STECH Cytochrome P450 1A1 OS=Stenotomus... | 507 | 3e-32 | 132 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
