| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53111 | 347 | ARI1_YEAST NADPH-dependent aldehyde reductase... | 376 | 5e-44 | 160 | 30 | 53 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044237; P:cellular metabolic process; IEA:InterPro. | 2 | Q12068 | 342 | GRE2_YEAST NADPH-dependent methylglyoxal redu... | 361 | 3e-43 | 158 | 32 | 50 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0046568; F:3-methylbutanol:NAD(P) oxidoreductase activity; IMP:SGD.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008204; P:ergosterol metabolic process; IMP:SGD.::GO:0030447; P:filamentous growth; IMP:SGD. | 3 | Q03049 | 344 | YD541_YEAST Putative uncharacterized oxidored... | 366 | 2e-41 | 153 | 30 | 50 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044237; P:cellular metabolic process; IEA:InterPro. | 4 | Q9UUN9 | 343 | ALD2_SPOSA Aldehyde reductase 2 OS=Sporobolom... | 359 | 3e-41 | 153 | 32 | 49 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044237; P:cellular metabolic process; IEA:InterPro. | 5 | Q9UT59 | 336 | YKJ7_SCHPO Putative uncharacterized oxidoredu... | 312 | 5e-41 | 152 | 33 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044237; P:cellular metabolic process; IEA:InterPro.::GO:0033554; P:cellular response to stress; IEP:PomBase. | 6 | P83775 | 341 | GRP2_CANAL Putative NADPH-dependent methylgly... | 332 | 7e-40 | 149 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:CGD. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044237; P:cellular metabolic process; IEA:InterPro. | 7 | P53183 | 348 | YGD9_YEAST Putative uncharacterized oxidoredu... | 376 | 1e-39 | 149 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006725; P:cellular aromatic compound metabolic process; IDA:SGD.::GO:0042180; P:cellular ketone metabolic process; IDA:SGD. | 8 | P51104 | 360 | DFRA_DIACA Dihydroflavonol-4-reductase OS=Dia... | 361 | 2e-25 | 108 | 28 | 46 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 9 | P51102 | 382 | DFRA_ARATH Dihydroflavonol-4-reductase OS=Ara... | 199 | 3e-23 | 102 | 35 | 54 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; TAS:TAIR. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; TAS:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009718; P:anthocyanin biosynthetic process; TAS:TAIR. | 10 | P14720 | 380 | DFRA_PETHY Dihydroflavonol-4-reductase OS=Pet... | 348 | 4e-23 | 102 | 28 | 46 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 11 | Q9XES5 | 348 | DFRA_MALDO Bifunctional dihydroflavonol 4-red... | 362 | 9e-23 | 100 | 26 | 47 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0047890; F:flavanone 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 12 | Q84KP0 | 347 | DFRA_PYRCO Bifunctional dihydroflavonol 4-red... | 362 | 1e-22 | 100 | 26 | 47 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0047890; F:flavanone 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 13 | P51105 | 366 | DFRA_GERHY Dihydroflavonol-4-reductase OS=Ger... | 350 | 2e-22 | 100 | 27 | 46 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 14 | P51107 | 379 | DFRA_SOLLC Dihydroflavonol-4-reductase OS=Sol... | 350 | 6e-21 | 96.3 | 27 | 45 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 15 | P51110 | 337 | DFRA_VITVI Dihydroflavonol-4-reductase OS=Vit... | 362 | 7e-21 | 95.1 | 26 | 44 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 16 | P51109 | 217 | DFRA_MEDSA Dihydroflavonol-4-reductase OS=Med... | 211 | 2e-20 | 91.7 | 32 | 49 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 17 | Q9SEV0 | 340 | BAN_ARATH Anthocyanidin reductase OS=Arabidop... | 277 | 3e-20 | 93.2 | 29 | 46 | | | | | | | | | | | GO:0033729; F:anthocyanidin reductase activity; IDA:TAIR.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.::GO:0009964; P:negative regulation of flavonoid biosynthetic process; IMP:TAIR. | 18 | P51106 | 354 | DFRA_HORVU Dihydroflavonol-4-reductase OS=Hor... | 203 | 2e-19 | 91.7 | 32 | 53 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 19 | O94563 | 336 | YGD4_SCHPO Putative uncharacterized oxidoredu... | 367 | 4e-19 | 90.1 | 29 | 42 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase. | 20 | P51103 | 364 | DFRA_CALCH Dihydroflavonol-4-reductase OS=Cal... | 281 | 5e-19 | 90.5 | 28 | 46 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 21 | P51108 | 357 | DFRA_MAIZE Dihydroflavonol-4-reductase OS=Zea... | 351 | 2e-18 | 88.6 | 26 | 44 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 22 | P14721 | 446 | DFRA_ANTMA Dihydroflavonol-4-reductase OS=Ant... | 353 | 3e-17 | 86.3 | 27 | 44 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 23 | Q3ZBE9 | 356 | NSDHL_BOVIN Sterol-4-alpha-carboxylate 3-dehy... | 198 | 0.00000005 | 57.8 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 24 | Q5PPL3 | 362 | NSDHL_RAT Sterol-4-alpha-carboxylate 3-dehydr... | 198 | 0.0000003 | 55.5 | 26 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 25 | Q9R1J0 | 362 | NSDHL_MOUSE Sterol-4-alpha-carboxylate 3-dehy... | 198 | 0.0000005 | 54.7 | 25 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0007224; P:smoothened signaling pathway; IGI:MGI. | 26 | P26439 | 372 | 3BHS2_HUMAN 3 beta-hydroxysteroid dehydrogena... | 222 | 0.0000007 | 54.3 | 29 | 44 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0030868; C:smooth endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 27 | Q5IFP1 | 373 | 3BHS_CANFA 3 beta-hydroxysteroid dehydrogenas... | 218 | 0.0000009 | 53.9 | 29 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 28 | O46516 | 373 | 3BHS_HORSE 3 beta-hydroxysteroid dehydrogenas... | 268 | 0.000001 | 53.9 | 28 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 29 | Q15738 | 373 | NSDHL_HUMAN Sterol-4-alpha-carboxylate 3-dehy... | 198 | 0.000001 | 53.5 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 30 | P73212 | 343 | DFRA_SYNY3 Putative dihydroflavonol-4-reducta... | 125 | 0.000001 | 53.1 | 30 | 46 | | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0045552; F:dihydrokaempferol 4-reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 31 | P14060 | 373 | 3BHS1_HUMAN 3 beta-hydroxysteroid dehydrogena... | 223 | 0.000001 | 53.1 | 28 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0030868; C:smooth endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004769; F:steroid delta-isomerase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:UniProtKB.::GO:0006703; P:estrogen biosynthetic process; TAS:UniProtKB.::GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. |
