rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q6DHL5 | 238 | LRC57_DANRE Leucine-rich repeat-containing pr... | 76 | 3.1 | 33.1 | 34 | 54 | | | | | | | | | | | | | | | | | | | | | | 362 | Q9NYK1 | 1049 | TLR7_HUMAN Toll-like receptor 7 OS=Homo sapie... | 225 | 0.12 | 38.5 | 27 | 43 | GO:0032009; C:early phagosome; ISS:UniProtKB.::GO:0036020; C:endolysosome membrane; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0035197; F:siRNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.::GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL. | 363 | Q80TM9 | 1593 | NISCH_MOUSE Nischarin OS=Mus musculus (Mouse)... | 129 | 0.37 | 37 | 29 | 51 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005178; F:integrin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI. | 364 | Q01129 | 354 | PGS2_RAT Decorin OS=Rattus norvegicus (Rat). ... | 239 | 0.001 | 44.3 | 29 | 46 | GO:0005589; C:collagen type VI; IDA:RGD. | | | | | | | | | | GO:0005518; F:collagen binding; IDA:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007519; P:skeletal muscle tissue development; IEP:RGD.::GO:0042060; P:wound healing; IEP:RGD. | 365 | Q6R5N8 | 991 | TLR13_MOUSE Toll-like receptor 13 OS=Mus musc... | 250 | 6.9 | 32.7 | 24 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 366 | Q8WUA8 | 353 | TSK_HUMAN Tsukushin OS=Homo sapiens (Human). ... | 283 | 0.001 | 44.3 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 367 | Q80WD1 | 420 | R4RL2_RAT Reticulon-4 receptor-like 2 OS=Ratt... | 207 | 0.001 | 44.3 | 29 | 45 | GO:0046658; C:anchored to plasma membrane; ISS:UniProtKB.::GO:0009897; C:external side of plasma membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD. | | | | | | | | | | GO:0004872; F:receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; NAS:RGD. | 368 | Q86UN3 | 420 | R4RL2_HUMAN Reticulon-4 receptor-like 2 OS=Ho... | 180 | 0.001 | 44.3 | 29 | 46 | GO:0046658; C:anchored to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004872; F:receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0031103; P:axon regeneration; TAS:UniProtKB. | 369 | Q29393 | 360 | PGS2_CANFA Decorin OS=Canis familiaris (Dog) ... | 64 | 3.4 | 33.5 | 39 | 55 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 370 | Q5M8M9 | 314 | LRC52_MOUSE Leucine-rich repeat-containing pr... | 150 | 0.001 | 43.9 | 33 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 371 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 73 | 7 | 32.7 | 33 | 56 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 372 | P51122 | 249 | AN32A_BOVIN Acidic leucine-rich nuclear phosp... | 62 | 0.002 | 43.5 | 42 | 61 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 373 | O75427 | 683 | LRCH4_HUMAN Leucine-rich repeat and calponin ... | 128 | 2.1 | 34.3 | 31 | 48 | GO:0016605; C:PML body; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007399; P:nervous system development; TAS:ProtInc. | 374 | Q6UWE0 | 723 | LRSM1_HUMAN E3 ubiquitin-protein ligase LRSAM... | 98 | 0.028 | 40.4 | 29 | 56 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005576; C:extracellular region; IEA:InterPro.::GO:0044425; C:membrane part; IDA:UniProtKB. | | | | | | | | | | GO:0005179; F:hormone activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045806; P:negative regulation of endocytosis; IMP:UniProtKB.::GO:0046755; P:non-lytic virus budding; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0070086; P:ubiquitin-dependent endocytosis; IDA:UniProtKB. | 375 | P39687 | 249 | AN32A_HUMAN Acidic leucine-rich nuclear phosp... | 62 | 0.002 | 43.5 | 42 | 61 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0006913; P:nucleocytoplasmic transport; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 376 | B6CZ54 | 192 | LRC51_PROCO Leucine-rich repeat-containing pr... | 93 | 0.002 | 42.7 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 377 | B6CZ45 | 192 | LRC51_MACMU Leucine-rich repeat-containing pr... | 93 | 0.002 | 42.7 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 378 | P0CE12 | 788 | SSPH2_SALTY E3 ubiquitin-protein ligase sspH2... | 204 | 0.022 | 40.8 | 27 | 45 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0009405; P:pathogenesis; ISS:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; ISS:UniProtKB. | 379 | D0ZPH9 | 788 | SSPH2_SALT1 E3 ubiquitin-protein ligase sspH2... | 204 | 0.022 | 40.8 | 27 | 45 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0009405; P:pathogenesis; IDA:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; IDA:UniProtKB. | 380 | Q8HY67 | 249 | AN32A_CANFA Acidic leucine-rich nuclear phosp... | 62 | 0.002 | 43.1 | 42 | 61 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 381 | B6CZ61 | 192 | LRC51_RAT Leucine-rich repeat-containing prot... | 93 | 0.002 | 42.4 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 382 | P21793 | 360 | PGS2_BOVIN Decorin OS=Bos taurus (Bovine). GN... | 64 | 1.2 | 34.7 | 41 | 55 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 383 | Q8N967 | 370 | LRTM2_HUMAN Leucine-rich repeat and transmemb... | 96 | 0.002 | 43.5 | 38 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 384 | Q5R1V9 | 359 | PGS2_PANTR Decorin OS=Pan troglodytes (Chimpa... | 64 | 1.3 | 34.7 | 39 | 56 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 385 | P07585 | 359 | PGS2_HUMAN Decorin OS=Homo sapiens (Human). G... | 64 | 1.3 | 34.7 | 39 | 56 | GO:0005615; C:extracellular space; IDA:BHF-UCL. | | | | | | | | | | | | | | | | | | | | GO:0009887; P:organ morphogenesis; TAS:ProtInc. | 386 | Q1EA11 | 687 | CCR4_COCIM Glucose-repressible alcohol dehydr... | 104 | 3.3 | 33.5 | 26 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 387 | Q99PI8 | 473 | RTN4R_MOUSE Reticulon-4 receptor OS=Mus muscu... | 160 | 0.002 | 43.5 | 29 | 44 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; IDA:MGI. | 388 | Q6ZVD8 | 1323 | PHLP2_HUMAN PH domain leucine-rich repeat-con... | 241 | 0.31 | 37 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 389 | Q9SSD1 | 496 | TMM_ARATH Protein TOO MANY MOUTHS OS=Arabidop... | 160 | 0.074 | 38.9 | 29 | 43 | GO:0031225; C:anchored to membrane; TAS:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0008356; P:asymmetric cell division; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR. | 390 | Q9TTE2 | 360 | PGS2_SHEEP Decorin OS=Ovis aries (Sheep). GN=... | 64 | 1.3 | 34.7 | 41 | 55 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 391 | Q99645 | 322 | EPYC_HUMAN Epiphycan OS=Homo sapiens (Human).... | 127 | 0.002 | 43.1 | 32 | 49 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc. |