rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | B5DF45 | 530 | TRAF6_RAT TNF receptor-associated factor 6 OS... | 34 | 0.39 | 37 | 41 | 59 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 62 | Q9FPH0 | 376 | XB34_ARATH Putative E3 ubiquitin-protein liga... | 70 | 0.39 | 37 | 40 | 44 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 63 | Q9UJV3 | 735 | TRIM1_HUMAN Probable E3 ubiquitin-protein lig... | 72 | 0.42 | 37 | 33 | 43 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 64 | O94271 | 673 | YORN_SCHPO Uncharacterized RING finger protei... | 69 | 0.43 | 37 | 32 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016567; P:protein ubiquitination; NAS:PomBase.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:PomBase. | 65 | Q568Y3 | 192 | RN185_RAT E3 ubiquitin-protein ligase RNF185 ... | 63 | 0.44 | 36.2 | 32 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 66 | Q96GF1 | 192 | RN185_HUMAN E3 ubiquitin-protein ligase RNF18... | 63 | 0.54 | 35.8 | 32 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 67 | Q7SZN2 | 266 | RN170_DANRE RING finger protein 170 OS=Danio ... | 82 | 0.57 | 36.2 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009790; P:embryo development; IMP:ZFIN. | 68 | Q9D9R0 | 233 | RN125_MOUSE E3 ubiquitin-protein ligase RNF12... | 70 | 0.58 | 35.8 | 30 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; EXP:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 69 | Q86XT4 | 487 | TRI50_HUMAN E3 ubiquitin-protein ligase TRIM5... | 61 | 0.66 | 36.2 | 34 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 70 | P22682 | 913 | CBL_MOUSE E3 ubiquitin-protein ligase CBL OS=... | 61 | 0.71 | 36.6 | 33 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB. | 71 | Q5RFK9 | 192 | RN185_PONAB E3 ubiquitin-protein ligase RNF18... | 63 | 0.71 | 35.4 | 32 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 72 | Q84RR0 | 562 | ARI7_ARATH Probable E3 ubiquitin-protein liga... | 67 | 0.71 | 36.2 | 36 | 45 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 73 | Q5ZIR9 | 194 | RN185_CHICK E3 ubiquitin-protein ligase RNF18... | 61 | 0.93 | 35 | 31 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 74 | Q95KF1 | 232 | RN125_MACFA E3 ubiquitin-protein ligase RNF12... | 68 | 0.94 | 35.4 | 31 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 75 | P36607 | 1133 | RAD5_SCHPO DNA repair protein rad5 OS=Schizos... | 38 | 0.95 | 36.2 | 39 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006289; P:nucleotide-excision repair; IMP:PomBase.::GO:0006301; P:postreplication repair; ISS:PomBase.::GO:0009650; P:UV protection; IMP:PomBase. | 76 | Q96EQ8 | 232 | RN125_HUMAN E3 ubiquitin-protein ligase RNF12... | 68 | 0.96 | 35.4 | 31 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome. | 77 | P40629 | 208 | 413R_IIV6 Putative RING finger protein 413R O... | 94 | 1 | 35 | 27 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 78 | Q8RXD4 | 941 | BRCA1_ARATH Protein BREAST CANCER SUSCEPTIBIL... | 59 | 1.1 | 35.8 | 29 | 41 | GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010332; P:response to gamma radiation; IEP:TAIR. | 79 | Q96EH8 | 262 | NEUL3_HUMAN E3 ubiquitin-protein ligase NEURL... | 59 | 1.1 | 35 | 32 | 42 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 80 | Q6PC78 | 194 | RN185_DANRE E3 ubiquitin-protein ligase RNF18... | 63 | 1.1 | 34.7 | 32 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW. | 81 | P22681 | 906 | CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=... | 61 | 1.1 | 35.8 | 33 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC. | 82 | Q3TTA7 | 982 | CBLB_MOUSE E3 ubiquitin-protein ligase CBL-B ... | 61 | 1.2 | 35.8 | 33 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006955; P:immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0042110; P:T cell activation; IMP:MGI. | 83 | Q6BIP2 | 1190 | RAD5_DEBHA DNA repair protein RAD5 OS=0083 / ... | 116 | 1.2 | 35.8 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 84 | Q8VYZ0 | 645 | ORTH2_ARATH E3 ubiquitin-protein ligase ORTHR... | 62 | 1.3 | 35.4 | 34 | 48 | GO:0010369; C:chromocenter; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:TAIR.::GO:0010385; F:double-stranded methylated DNA binding; IDA:TAIR.::GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IDA:TAIR.::GO:0031508; P:centromeric heterochromatin assembly; IMP:TAIR.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:UniProtKB.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB. | 85 | Q14258 | 630 | TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ... | 32 | 1.3 | 35.4 | 53 | 59 | GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 86 | Q8GUK7 | 243 | RMA3_ARATH E3 ubiquitin-protein ligase RMA3 O... | 61 | 1.3 | 35 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 87 | Q8NA82 | 808 | MARHA_HUMAN Probable E3 ubiquitin-protein lig... | 62 | 1.4 | 35.4 | 34 | 47 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 88 | Q13191 | 982 | CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B ... | 61 | 1.4 | 35.4 | 33 | 38 | | | | | | | | | | | | | | | | | | | | | | 89 | Q8K4S7 | 938 | CBLB_RAT E3 ubiquitin-protein ligase CBL-B OS... | 61 | 1.5 | 35.4 | 33 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD. | 90 | Q6NRE7 | 764 | CBLBB_XENLA E3 ubiquitin-protein ligase CBL-B... | 77 | 1.6 | 35.4 | 31 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro. | 91 | Q6MFY8 | 247 | TRI40_RAT Tripartite motif-containing protein... | 57 | 1.6 | 34.7 | 35 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |