| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A5DP36 | 1440 | PAN1_PICGU Actin cytoskeleton-regulatory comp... | 91 | 0.00005 | 51.6 | 31 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 32 | Q54KI4 | 1196 | EPS15_DICDI Epidermal growth factor receptor ... | 96 | 0.05 | 41.6 | 32 | 47 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 33 | A7TSV7 | 1492 | PAN1_VANPO Actin cytoskeleton-regulatory comp... | 85 | 0.000006 | 54.7 | 36 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 34 | Q5AHB1 | 1397 | PAN1_CANAL Actin cytoskeleton-regulatory comp... | 90 | 0.0006 | 48.1 | 32 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030427; C:site of polarized growth; IDA:CGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:CGD.::GO:0009826; P:unidimensional cell growth; IMP:CGD. | 35 | Q6C370 | 400 | END3_YARLI Actin cytoskeleton-regulatory comp... | 70 | 0.000003 | 54.7 | 40 | 57 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 36 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 62 | 3.6 | 35.8 | 29 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 37 | P32521 | 1480 | PAN1_YEAST Actin cytoskeleton-regulatory comp... | 137 | 0.00006 | 51.2 | 31 | 46 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0007120; P:axial cellular bud site selection; IMP:SGD.::GO:0007121; P:bipolar cellular bud site selection; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD. | 38 | A5DVD6 | 1505 | PAN1_LODEL Actin cytoskeleton-regulatory comp... | 85 | 0.028 | 42.7 | 31 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 39 | Q10172 | 1794 | PAN1_SCHPO Actin cytoskeleton-regulatory comp... | 186 | 0.0004 | 48.5 | 25 | 45 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase. | 40 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 62 | 3.1 | 35.8 | 29 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 41 | Q2H2V8 | 402 | END3_CHAGB Actin cytoskeleton-regulatory comp... | 200 | 0.089 | 40.4 | 27 | 43 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 42 | Q641Z6 | 534 | EHD1_RAT EH domain-containing protein 1 OS=Ra... | 68 | 1.7 | 36.6 | 34 | 50 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 43 | Q9WVK4 | 534 | EHD1_MOUSE EH domain-containing protein 1 OS=... | 68 | 1.7 | 36.6 | 34 | 50 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005811; C:lipid particle; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0031095; C:platelet dense tubular network membrane; IDA:BHF-UCL.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; IMP:BHF-UCL. | 44 | Q5RBP4 | 534 | EHD1_PONAB EH domain-containing protein 1 OS=... | 68 | 1.3 | 37 | 34 | 50 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 45 | Q9H4M9 | 534 | EHD1_HUMAN EH domain-containing protein 1 OS=... | 68 | 1.3 | 37 | 34 | 50 | GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005811; C:lipid particle; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031095; C:platelet dense tubular network membrane; ISS:BHF-UCL.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.::GO:0032456; P:endocytic recycling; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:UniProtKB.::GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; ISS:BHF-UCL.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 46 | Q75AA0 | 1203 | PAN1_ASHGO Actin cytoskeleton-regulatory comp... | 60 | 0.006 | 44.7 | 38 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 47 | Q6CQX9 | 1324 | PAN1_KLULA Actin cytoskeleton-regulatory comp... | 89 | 0.00002 | 52.8 | 34 | 52 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 48 | Q5E9R3 | 534 | EHD1_BOVIN EH domain-containing protein 1 OS=... | 68 | 1.3 | 37 | 34 | 50 | GO:0031901; C:early endosome membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB. | 49 | Q9NZN3 | 535 | EHD3_HUMAN EH domain-containing protein 3 OS=... | 68 | 0.76 | 37.7 | 35 | 49 | GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0032456; P:endocytic recycling; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 50 | Q6FPQ7 | 1374 | PAN1_CANGA Actin cytoskeleton-regulatory comp... | 88 | 0.0007 | 47.8 | 33 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 51 | Q9QXY6 | 535 | EHD3_MOUSE EH domain-containing protein 3 OS=... | 68 | 0.41 | 38.5 | 35 | 51 | GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 52 | Q8R491 | 535 | EHD3_RAT EH domain-containing protein 3 OS=Ra... | 68 | 0.43 | 38.5 | 35 | 51 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 53 | Q7S9V9 | 396 | END3_NEUCR Actin cytoskeleton-regulatory comp... | 206 | 2.5 | 35.8 | 22 | 37 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 54 | A6ZVS5 | 1460 | PAN1_YEAS7 Actin cytoskeleton-regulatory comp... | 137 | 0.00007 | 51.2 | 31 | 46 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 55 | Q9H223 | 541 | EHD4_HUMAN EH domain-containing protein 4 OS=... | 68 | 0.13 | 40 | 35 | 57 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032456; P:endocytic recycling; IGI:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB. | 56 | Q4V8H8 | 543 | EHD2_RAT EH domain-containing protein 2 OS=Ra... | 68 | 0.017 | 43.1 | 38 | 50 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB. | 57 | Q8BH64 | 543 | EHD2_MOUSE EH domain-containing protein 2 OS=... | 68 | 0.015 | 43.1 | 38 | 50 | GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IDA:MGI. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IDA:MGI.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI. | 58 | Q9EQP2 | 541 | EHD4_MOUSE EH domain-containing protein 4 OS=... | 68 | 0.21 | 39.3 | 35 | 56 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 59 | Q9USZ7 | 375 | END3_SCHPO Actin cytoskeleton-regulatory comp... | 96 | 0.00002 | 52 | 31 | 54 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase. | 60 | Q5EN00 | 396 | END3_MAGO7 Actin cytoskeleton-regulatory comp... | 159 | 0.75 | 37.4 | 27 | 43 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 61 | Q96D71 | 796 | REPS1_HUMAN RalBP1-associated Eps domain-cont... | 97 | 0.24 | 39.3 | 28 | 51 | GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | |
