rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q91XS1 | 1190 | MTMR4_MOUSE Myotubularin-related protein 4 OS... | 48 | 0.079 | 40 | 40 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 62 | O13821 | 610 | VPS27_SCHPO Vacuolar protein sorting-associat... | 36 | 0.081 | 39.7 | 53 | 58 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:PomBase.::GO:0043130; F:ubiquitin binding; IMP:PomBase. | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0045053; P:protein retention in Golgi apparatus; ISS:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 63 | Q5ABD9 | 841 | VPS27_CANAL Vacuolar protein sorting-associat... | 27 | 0.083 | 39.7 | 52 | 67 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0009405; P:pathogenesis; IMP:CGD. | 64 | Q9TZD0 | 661 | LST2_CAEEL Lateral signaling target protein 2... | 62 | 0.085 | 39.7 | 34 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase. | | | | | | | | | | GO:0040027; P:negative regulation of vulval development; IMP:WormBase. | 65 | P98174 | 961 | FGD1_HUMAN FYVE, RhoGEF and PH domain-contain... | 33 | 0.099 | 39.7 | 36 | 61 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 66 | Q8IZQ1 | 3526 | WDFY3_HUMAN WD repeat and FYVE domain-contain... | 35 | 0.11 | 39.7 | 46 | 51 | GO:0044444; C:cytoplasmic part; IDA:MGI.::GO:0019898; C:extrinsic to membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 67 | Q6VNB8 | 3508 | WDFY3_MOUSE WD repeat and FYVE domain-contain... | 35 | 0.12 | 39.3 | 46 | 51 | | | | | | | | | | | GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 68 | Q0P4S0 | 951 | LST2_XENTR Lateral signaling target protein 2... | 36 | 0.12 | 39.3 | 47 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 69 | Q7Z3T8 | 1539 | ZFY16_HUMAN Zinc finger FYVE domain-containin... | 45 | 0.14 | 39.3 | 36 | 47 | GO:0031901; C:early endosome membrane; TAS:Reactome. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IMP:UniProtKB. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0016050; P:vesicle organization; NAS:UniProtKB. | 70 | Q9HCC9 | 887 | LST2_HUMAN Lateral signaling target protein 2... | 36 | 0.14 | 38.9 | 47 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB. | 71 | Q80U44 | 1528 | ZFY16_MOUSE Zinc finger FYVE domain-containin... | 45 | 0.17 | 38.9 | 36 | 47 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 72 | A0JMD2 | 969 | LST2_DANRE Lateral signaling target protein 2... | 36 | 0.17 | 38.9 | 47 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 73 | Q6ZPK7 | 905 | LST2_MOUSE Lateral signaling target protein 2... | 36 | 0.18 | 38.5 | 47 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 74 | Q0V8S0 | 777 | HGS_BOVIN Hepatocyte growth factor-regulated ... | 56 | 0.18 | 38.5 | 36 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 75 | O14964 | 777 | HGS_HUMAN Hepatocyte growth factor-regulated ... | 56 | 0.2 | 38.5 | 36 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.::GO:0042176; P:regulation of protein catabolic process; TAS:HGNC. | 76 | B4PRU6 | 984 | LST2_DROYA Lateral signaling target protein 2... | 37 | 0.2 | 38.5 | 38 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 77 | B3P851 | 981 | LST2_DROER Lateral signaling target protein 2... | 37 | 0.2 | 38.5 | 38 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 78 | Q9VB70 | 989 | LST2_DROME Lateral signaling target protein 2... | 37 | 0.2 | 38.5 | 38 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 79 | B4IC49 | 975 | LST2_DROSE Lateral signaling target protein 2... | 37 | 0.21 | 38.5 | 38 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 80 | Q960X8 | 760 | HRS_DROME Hepatocyte growth factor-regulated ... | 35 | 0.26 | 38.1 | 51 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; NAS:FlyBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0006897; P:endocytosis; IMP:FlyBase.::GO:0016197; P:endosome transport; TAS:FlyBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; NAS:FlyBase.::GO:0045752; P:positive regulation of Toll signaling pathway; IMP:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0016050; P:vesicle organization; NAS:FlyBase. | 81 | Q9JJ50 | 776 | HGS_RAT Hepatocyte growth factor-regulated ty... | 56 | 0.31 | 37.7 | 36 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 82 | O95405 | 1425 | ZFYV9_HUMAN Zinc finger FYVE domain-containin... | 57 | 0.31 | 38.1 | 32 | 44 | GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 83 | B3MT31 | 985 | LST2_DROAN Lateral signaling target protein 2... | 37 | 0.31 | 37.7 | 38 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 84 | Q9H8W4 | 249 | PKHF2_HUMAN Pleckstrin homology domain-contai... | 53 | 0.32 | 37 | 34 | 45 | GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 85 | Q91WB4 | 249 | PKHF2_MOUSE Pleckstrin homology domain-contai... | 53 | 0.32 | 37 | 34 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 86 | Q7ZUV1 | 247 | PKHF2_DANRE Pleckstrin homology domain-contai... | 54 | 0.32 | 37 | 37 | 48 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 87 | Q5BBK9 | 715 | VPS27_EMENI Vacuolar protein sorting-associat... | 74 | 0.33 | 37.7 | 31 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 88 | Q99LI8 | 775 | HGS_MOUSE Hepatocyte growth factor-regulated ... | 56 | 0.33 | 37.7 | 36 | 45 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 89 | B4JHI7 | 1115 | LST2_DROGR Lateral signaling target protein 2... | 37 | 0.33 | 37.7 | 38 | 51 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | Q5ZLY5 | 249 | PKHF2_CHICK Pleckstrin homology domain-contai... | 53 | 0.35 | 37 | 34 | 45 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 91 | Q2GS33 | 737 | VPS27_CHAGB Vacuolar protein sorting-associat... | 84 | 0.37 | 37.7 | 36 | 42 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |