| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
781 | Q14680 | 651 | MELK_HUMAN Maternal embryonic leucine zipper ... | 152 | 0.0000004 | 57.4 | 24 | 47 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 782 | Q5UQ78 | 450 | YR517_MIMIV Putative serine/threonine-protein... | 275 | 0.0000004 | 57 | 20 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 783 | Q8RWL2 | 534 | CDPKT_ARATH Calcium-dependent protein kinase ... | 323 | 0.0000004 | 57.4 | 24 | 41 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 784 | A8WYE4 | 1088 | PAR1_CAEBR Serine/threonine-protein kinase pa... | 173 | 0.0000004 | 57.8 | 24 | 45 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 785 | P19784 | 350 | CSK22_HUMAN Casein kinase II subunit alpha' O... | 210 | 0.0000004 | 56.6 | 23 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 786 | Q8BI55 | 632 | DYRK4_MOUSE Dual specificity tyrosine-phospho... | 200 | 0.0000004 | 57.4 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 787 | Q23023 | 856 | UNC51_CAEEL Serine/threonine-protein kinase u... | 184 | 0.0000004 | 57.4 | 23 | 43 | GO:0030424; C:axon; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IMP:WormBase.::GO:0006914; P:autophagy; IGI:WormBase.::GO:0048675; P:axon extension; IMP:WormBase.::GO:0007411; P:axon guidance; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0040024; P:dauer larval development; IGI:WormBase.::GO:0008340; P:determination of adult lifespan; IGI:WormBase.::GO:0070265; P:necrotic cell death; IMP:WormBase.::GO:0012501; P:programmed cell death; IGI:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0030516; P:regulation of axon extension; IMP:WormBase.::GO:0040014; P:regulation of multicellular organism growth; IGI:WormBase.::GO:0032880; P:regulation of protein localization; IMP:WormBase.::GO:0035121; P:tail morphogenesis; IMP:WormBase. | 788 | Q9FJV0 | 356 | M2K6_ARATH Mitogen-activated protein kinase k... | 165 | 0.0000004 | 56.6 | 24 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 789 | Q750A9 | 447 | HOG1_ASHGO Mitogen-activated protein kinase H... | 96 | 0.0000004 | 57 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 790 | Q63092 | 504 | CAMKV_RAT CaM kinase-like vesicle-associated ... | 219 | 0.0000004 | 57 | 24 | 42 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | | 791 | Q08DZ2 | 1008 | PRP4B_BOVIN Serine/threonine-protein kinase P... | 175 | 0.0000004 | 57.4 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 792 | Q5RKH1 | 1007 | PRP4B_RAT Serine/threonine-protein kinase PRP... | 175 | 0.0000004 | 57.4 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 793 | Q86YV6 | 388 | MYLK4_HUMAN Myosin light chain kinase family ... | 215 | 0.0000004 | 56.6 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 794 | Q9HG11 | 415 | MPKC_EMENI Mitogen-activated protein kinase m... | 96 | 0.0000004 | 56.6 | 26 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 795 | Q91ZN7 | 476 | CHK1_RAT Serine/threonine-protein kinase Chk1... | 131 | 0.0000004 | 57 | 29 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; IEP:RGD.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:RGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:RGD.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:RGD.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB. | 796 | Q8SSA8 | 414 | CHK1_ENCCU Probable serine/threonine-protein ... | 123 | 0.0000004 | 56.6 | 26 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 797 | Q2RAX3 | 454 | CIPKX_ORYSJ CBL-interacting protein kinase 33... | 126 | 0.0000004 | 56.6 | 27 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 798 | Q54VU4 | 1505 | Y8013_DICDI Probable serine/threonine-protein... | 270 | 0.0000005 | 57.4 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 799 | Q7XKA8 | 370 | SAPK5_ORYSJ Serine/threonine-protein kinase S... | 205 | 0.0000005 | 56.6 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW. | 800 | P53350 | 603 | PLK1_HUMAN Serine/threonine-protein kinase PL... | 210 | 0.0000005 | 57 | 20 | 44 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000942; C:condensed nuclear chromosome outer kinetochore; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0051233; C:spindle midzone; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0051297; P:centrosome organization; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.::GO:0007091; P:mitotic metaphase/anaphase transition; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0000088; P:mitotic prophase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.::GO:0031648; P:protein destabilization; IDA:UniProtKB.::GO:0071168; P:protein localization to chromatin; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0090007; P:regulation of mitotic anaphase; IMP:BHF-UCL.::GO:0043393; P:regulation of protein binding; IMP:BHF-UCL. | 801 | P21868 | 391 | CSK21_CHICK Casein kinase II subunit alpha OS... | 210 | 0.0000005 | 56.6 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 802 | Q61136 | 1007 | PRP4B_MOUSE Serine/threonine-protein kinase P... | 175 | 0.0000005 | 57.4 | 26 | 46 | GO:0005694; C:chromosome; IDA:MGI.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 803 | Q9TW45 | 1192 | PAR1_CAEEL Serine/threonine-protein kinase pa... | 173 | 0.0000005 | 57.4 | 24 | 45 | GO:0005938; C:cell cortex; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0009949; P:polarity specification of anterior/posterior axis; TAS:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 804 | B5DK35 | 755 | DCLK_DROPS Serine/threonine-protein kinase GA... | 125 | 0.0000005 | 57 | 26 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 805 | Q16566 | 473 | KCC4_HUMAN Calcium/calmodulin-dependent prote... | 185 | 0.0000005 | 56.6 | 25 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; IGI:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; TAS:UniProtKB.::GO:0033081; P:regulation of T cell differentiation in thymus; TAS:UniProtKB. | 806 | Q8T2I8 | 1167 | SEPA_DICDI Serine/threonine-protein kinase se... | 175 | 0.0000005 | 57.4 | 24 | 47 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 807 | B4GXC2 | 755 | DCLK_DROPE Serine/threonine-protein kinase GL... | 125 | 0.0000005 | 57 | 26 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 808 | Q10LQ2 | 451 | CIPKA_ORYSJ CBL-interacting protein kinase 10... | 201 | 0.0000005 | 56.6 | 24 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 809 | Q3UTQ8 | 938 | CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS... | 220 | 0.0000005 | 57 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 810 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 230 | 0.0000005 | 57 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 811 | Q61XD3 | 302 | AIR2_CAEBR Aurora/IPL1-related protein kinase... | 220 | 0.0000005 | 55.8 | 23 | 42 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. |
