rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
721 | P05180 | 491 | CP2H1_CHICK Cytochrome P450 2H1 OS=Gallus gal... | 268 | 0.000001 | 54.7 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 722 | P04167 | 491 | CP2B2_RAT Cytochrome P450 2B2 OS=Rattus norve... | 187 | 0.000001 | 54.3 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0018933; P:nicotine metabolic process; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 723 | O46491 | 501 | CP7A1_PIG Cholesterol 7-alpha-monooxygenase O... | 210 | 0.000001 | 54.3 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; ISS:UniProtKB.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; ISS:UniProtKB. | 724 | P11371 | 487 | CP2C4_RABIT Cytochrome P450 2C4 OS=Oryctolagu... | 202 | 0.000001 | 54.3 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 725 | Q9M7B7 | 541 | C79D2_MANES Valine N-monooxygenase 2 OS=Manih... | 204 | 0.000002 | 54.3 | 22 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:UniProtKB.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019756; P:cyanogenic glycoside biosynthetic process; IDA:UniProtKB. | 726 | Q9C5Y2 | 489 | KAO2_ARATH Ent-kaurenoic acid oxidase 2 OS=Ar... | 448 | 0.000002 | 54.3 | 23 | 35 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051777; F:ent-kaurenoate oxidase activity; IDA:TAIR.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009686; P:gibberellin biosynthetic process; TAS:TAIR. | 727 | Q6ZSU1 | 146 | C2G1P_HUMAN Putative cytochrome P450 2G1 OS=H... | 108 | 0.000002 | 51.6 | 31 | 53 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 728 | Q95M61 | 503 | CP19A_CALJA Cytochrome P450 19A1 OS=Callithri... | 184 | 0.000002 | 54.3 | 26 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 729 | Q54E98 | 481 | C520B_DICDI Putative cytochrome P450 520B1 OS... | 228 | 0.000002 | 54.3 | 23 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 730 | P05178 | 490 | CP2C6_RAT Cytochrome P450 2C6 OS=Rattus norve... | 176 | 0.000002 | 53.9 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 731 | P33272 | 492 | CP2BC_RAT Cytochrome P450 2B12 OS=Rattus norv... | 207 | 0.000002 | 53.9 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 732 | Q29527 | 503 | C11B1_PAPHU Cytochrome P450 11B1, mitochondri... | 233 | 0.000002 | 53.9 | 25 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 733 | Q9JKJ9 | 470 | CP39A_MOUSE 24-hydroxycholesterol 7-alpha-hyd... | 178 | 0.000002 | 53.9 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033782; F:24-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB.::GO:0008387; F:steroid 7-alpha-hydroxylase activity; IDA:MGI. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0006707; P:cholesterol catabolic process; IDA:MGI.::GO:0007586; P:digestion; TAS:UniProtKB. | 734 | Q6XQ14 | 511 | C71E7_MANES 2-methylbutanal oxime monooxygena... | 204 | 0.000002 | 53.9 | 23 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC. | | | | | | | | | | | 735 | Q9FMA5 | 465 | C85A1_ARATH Cytochrome P450 85A1 OS=Arabidops... | 219 | 0.000002 | 53.9 | 22 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:TAIR.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IDA:TAIR.::GO:0010268; P:brassinosteroid homeostasis; IEP:TAIR. | 736 | P33261 | 490 | CP2CJ_HUMAN Cytochrome P450 2C19 OS=Homo sapi... | 179 | 0.000002 | 53.5 | 25 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0052741; F:(R)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018675; F:(S)-limonene 6-monooxygenase activity; IEA:EC.::GO:0018676; F:(S)-limonene 7-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL. | | | | | | | | | | GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 737 | O35074 | 501 | PTGIS_MOUSE Prostacyclin synthase OS=Mus musc... | 184 | 0.000002 | 53.5 | 26 | 46 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 738 | O44220 | 532 | C12B1_DROAC Cytochrome P450 12b1, mitochondri... | 505 | 0.000002 | 53.9 | 21 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 739 | Q43255 | 536 | C71C2_MAIZE indolin-2-one monooxygenase OS=Ze... | 188 | 0.000003 | 53.5 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 740 | O62671 | 489 | CP241_CANFA Cytochrome P450 2C41 OS=Canis fam... | 176 | 0.000003 | 53.5 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 741 | P85191 | 155 | CP450_HELAN Cytochrome P450 OS=Helianthus ann... | 124 | 0.000003 | 50.8 | 23 | 48 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 742 | P93703 | 535 | C71C3_MAIZE Cytochrome P450 71C3 OS=Zea mays ... | 201 | 0.000003 | 53.5 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 743 | P20678 | 491 | CP2H2_CHICK Cytochrome P450 2H2 OS=Gallus gal... | 174 | 0.000003 | 53.1 | 26 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 744 | P90771 | 493 | C36A1_CAEEL Probable cytochrome P450 CYP36A1 ... | 208 | 0.000003 | 53.1 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 745 | P37114 | 506 | TCMO_MEDSA Trans-cinnamate 4-monooxygenase OS... | 200 | 0.000003 | 53.1 | 27 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | | 746 | O08469 | 410 | CPXY_BACSU Cytochrome P450 OS=Bacillus subtil... | 200 | 0.000004 | 52.8 | 28 | 47 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 747 | P11511 | 503 | CP19A_HUMAN Cytochrome P450 19A1 OS=Homo sapi... | 196 | 0.000004 | 53.1 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 748 | Q62969 | 501 | PTGIS_RAT Prostacyclin synthase OS=Rattus nor... | 144 | 0.000004 | 52.8 | 29 | 49 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; IMP:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 749 | Q9FH66 | 497 | C71AG_ARATH Cytochrome P450 71A16 OS=Arabidop... | 259 | 0.000005 | 52.8 | 22 | 39 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 750 | Q9VW43 | 504 | CP305_DROME Probable cytochrome P450 305a1 OS... | 174 | 0.000005 | 52.8 | 29 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 751 | Q1ZXG6 | 509 | C5131_DICDI Probable cytochrome P450 513A1 OS... | 199 | 0.000006 | 52.4 | 25 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |