| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P41499 | 597 | PTN11_RAT Tyrosine-protein phosphatase non-re... | 277 | 2e-23 | 110 | 29 | 40 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0043274; F:phospholipase binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB. | 62 | Q4JDL3 | 420 | PTN20_HUMAN Tyrosine-protein phosphatase non-... | 272 | 2e-23 | 108 | 28 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 63 | Q06124 | 597 | PTN11_HUMAN Tyrosine-protein phosphatase non-... | 277 | 2e-23 | 110 | 29 | 40 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 64 | Q12923 | 2485 | PTN13_HUMAN Tyrosine-protein phosphatase non-... | 285 | 2e-23 | 112 | 28 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 65 | Q15262 | 1439 | PTPRK_HUMAN Receptor-type tyrosine-protein ph... | 34 | 0.8 | 38.1 | 41 | 71 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 66 | P28828 | 1452 | PTPRM_MOUSE Receptor-type tyrosine-protein ph... | 34 | 0.59 | 38.5 | 38 | 74 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB. | 67 | E9Q612 | 1226 | PTPRO_MOUSE Receptor-type tyrosine-protein ph... | 276 | 4e-23 | 110 | 30 | 43 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0043197; C:dendritic spine; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0017147; F:Wnt-protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0002548; P:monocyte chemotaxis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; IMP:UniProtKB. | 68 | P35233 | 416 | PTN2_RAT Tyrosine-protein phosphatase non-rec... | 289 | 4e-23 | 107 | 26 | 39 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | | 69 | Q61152 | 453 | PTN18_MOUSE Tyrosine-protein phosphatase non-... | 266 | 4e-23 | 107 | 30 | 40 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 70 | P27574 | 550 | PYP1_SCHPO Tyrosine-protein phosphatase 1 OS=... | 123 | 0.0000000008 | 67 | 33 | 54 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:PomBase.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase. | 71 | P28192 | 1159 | PTP2_CAEEL Tyrosine-protein phosphatase 2 OS=... | 273 | 9e-23 | 109 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 72 | Q06180 | 406 | PTN2_MOUSE Tyrosine-protein phosphatase non-r... | 289 | 1e-22 | 106 | 26 | 39 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI. | 73 | Q63475 | 1004 | PTPR2_RAT Receptor-type tyrosine-protein phos... | 338 | 1e-22 | 108 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034260; P:negative regulation of GTPase activity; IDA:RGD. | 74 | P18052 | 829 | PTPRA_MOUSE Receptor-type tyrosine-protein ph... | 276 | 5e-17 | 90.9 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 75 | P17706 | 415 | PTN2_HUMAN Tyrosine-protein phosphatase non-r... | 288 | 2e-22 | 105 | 26 | 40 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome. | 76 | Q16849 | 979 | PTPRN_HUMAN Receptor-type tyrosine-protein ph... | 286 | 2e-22 | 108 | 26 | 40 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB. | 77 | Q16827 | 1216 | PTPRO_HUMAN Receptor-type tyrosine-protein ph... | 276 | 2e-22 | 108 | 30 | 42 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0030424; C:axon; ISS:UniProtKB.::GO:0043197; C:dendritic spine; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0016328; C:lateral plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0017147; F:Wnt-protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0002548; P:monocyte chemotaxis; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; ISS:UniProtKB. | 78 | P56722 | 979 | PTPRN_BOVIN Receptor-type tyrosine-protein ph... | 286 | 2e-22 | 108 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB. | 79 | Q63259 | 983 | PTPRN_RAT Receptor-type tyrosine-protein phos... | 286 | 3e-22 | 108 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD. | 80 | Q9IBD8 | 1216 | PTPRC_CYPCA Receptor-type tyrosine-protein ph... | 250 | 0.00000005 | 61.6 | 22 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro. | 81 | P26045 | 913 | PTN3_HUMAN Tyrosine-protein phosphatase non-r... | 291 | 4e-22 | 107 | 27 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL. | 82 | Q60673 | 979 | PTPRN_MOUSE Receptor-type tyrosine-protein ph... | 286 | 4e-22 | 107 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI. | 83 | P43378 | 593 | PTN9_HUMAN Tyrosine-protein phosphatase non-r... | 274 | 4e-22 | 106 | 28 | 42 | GO:0044444; C:cytoplasmic part; IDA:UniProtKB. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 84 | Q641Z2 | 593 | PTN9_RAT Tyrosine-protein phosphatase non-rec... | 270 | 5e-22 | 106 | 29 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 85 | P35822 | 1457 | PTPRK_MOUSE Receptor-type tyrosine-protein ph... | 34 | 0.79 | 38.1 | 41 | 71 | GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | P80560 | 1001 | PTPR2_MOUSE Receptor-type tyrosine-protein ph... | 294 | 5e-22 | 107 | 27 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | A2ALK8 | 913 | PTN3_MOUSE Tyrosine-protein phosphatase non-r... | 292 | 6e-22 | 106 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 88 | O35239 | 593 | PTN9_MOUSE Tyrosine-protein phosphatase non-r... | 274 | 1e-21 | 104 | 28 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 89 | O02695 | 1013 | PTPR2_MACNE Receptor-type tyrosine-protein ph... | 283 | 2e-21 | 105 | 27 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | Q62136 | 1176 | PTN21_MOUSE Tyrosine-protein phosphatase non-... | 282 | 2e-21 | 105 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 91 | Q92932 | 1015 | PTPR2_HUMAN Receptor-type tyrosine-protein ph... | 286 | 2e-21 | 104 | 26 | 39 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | |
