| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q12913 | 1337 | PTPRJ_HUMAN Receptor-type tyrosine-protein ph... | 276 | 3e-25 | 118 | 30 | 43 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0060242; P:contact inhibition; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045885; P:positive regulation of survival gene product expression; IDA:UniProtKB. | 32 | P08575 | 1304 | PTPRC_HUMAN Receptor-type tyrosine-protein ph... | 298 | 0.00000000001 | 73.6 | 22 | 36 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0048539; P:bone marrow development; IMP:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:UniProtKB.::GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.::GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0048864; P:stem cell development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 33 | Q62130 | 1189 | PTN14_MOUSE Tyrosine-protein phosphatase non-... | 319 | 3e-25 | 117 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0001946; P:lymphangiogenesis; IMP:UniProtKB. | 34 | Q64455 | 1238 | PTPRJ_MOUSE Receptor-type tyrosine-protein ph... | 276 | 3e-25 | 117 | 29 | 42 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI. | 35 | P06800 | 1291 | PTPRC_MOUSE Receptor-type tyrosine-protein ph... | 220 | 0.000000004 | 65.5 | 23 | 36 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 36 | P28191 | 1026 | PTP1_CAEEL Tyrosine-protein phosphatase 1 OS=... | 285 | 5e-25 | 117 | 28 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 37 | Q9HD43 | 1115 | PTPRH_HUMAN Receptor-type tyrosine-protein ph... | 282 | 5e-25 | 117 | 30 | 40 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 38 | P16621 | 2029 | LAR_DROME Tyrosine-protein phosphatase Lar OS... | 343 | 7e-20 | 100 | 26 | 38 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0032093; F:SAM domain binding; IPI:FlyBase. | | | | | | | | | | GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; NAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0045467; P:R7 cell development; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase. | 39 | Q9WU22 | 926 | PTN4_MOUSE Tyrosine-protein phosphatase non-r... | 291 | 1e-24 | 115 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | | 40 | P49446 | 699 | PTPRE_MOUSE Receptor-type tyrosine-protein ph... | 276 | 2e-16 | 89 | 25 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI. | 41 | P10586 | 1907 | PTPRF_HUMAN Receptor-type tyrosine-protein ph... | 273 | 4e-24 | 114 | 29 | 41 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 42 | A4IFW2 | 1909 | PTPRF_DANRE Receptor-type tyrosine-protein ph... | 277 | 2e-24 | 115 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 43 | B2GV87 | 699 | PTPRE_RAT Receptor-type tyrosine-protein phos... | 276 | 2e-16 | 88.6 | 25 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 44 | P35831 | 775 | PTN12_MOUSE Tyrosine-protein phosphatase non-... | 275 | 2e-24 | 114 | 27 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 45 | Q05209 | 780 | PTN12_HUMAN Tyrosine-protein phosphatase non-... | 87 | 1.4 | 37 | 29 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | | 46 | Q64512 | 2453 | PTN13_MOUSE Tyrosine-protein phosphatase non-... | 284 | 2e-24 | 115 | 28 | 38 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 47 | P35832 | 1301 | PTP99_DROME Tyrosine-protein phosphatase 99A ... | 83 | 0.0001 | 50.4 | 30 | 51 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:FlyBase. | | | | | | | | | | GO:0007415; P:defasciculation of motor neuron axon; IGI:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase. | 48 | Q9W0G1 | 548 | PTP61_DROME Tyrosine-protein phosphatase non-... | 265 | 3e-24 | 112 | 28 | 42 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase. | | | | | | | | | | GO:0007411; P:axon guidance; IPI:FlyBase.::GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007377; P:germ-band extension; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase. | 49 | P23468 | 1912 | PTPRD_HUMAN Receptor-type tyrosine-protein ph... | 277 | 3e-23 | 111 | 28 | 40 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 50 | P23469 | 700 | PTPRE_HUMAN Receptor-type tyrosine-protein ph... | 276 | 7e-16 | 86.7 | 25 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 51 | Q90687 | 593 | PTN11_CHICK Tyrosine-protein phosphatase non-... | 277 | 4e-24 | 112 | 29 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 52 | Q64487 | 1912 | PTPRD_MOUSE Receptor-type tyrosine-protein ph... | 277 | 3e-23 | 111 | 28 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 53 | O14522 | 1441 | PTPRT_HUMAN Receptor-type tyrosine-protein ph... | 34 | 0.24 | 39.7 | 44 | 74 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045296; F:cadherin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB. | 54 | Q99M80 | 1454 | PTPRT_MOUSE Receptor-type tyrosine-protein ph... | 34 | 0.22 | 39.7 | 44 | 74 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0051393; F:alpha-actinin binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0045296; F:cadherin binding; IPI:MGI.::GO:0070097; F:delta-catenin binding; IPI:MGI.::GO:0045295; F:gamma-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016790; F:thiolester hydrolase activity; IDA:MGI. | | | | | | | | | | | 55 | P35992 | 1631 | PTP10_DROME Tyrosine-protein phosphatase 10D ... | 274 | 7e-24 | 113 | 28 | 41 | GO:0045177; C:apical part of cell; IDA:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase. | | | | | | | | | | GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IGI:FlyBase. | 56 | Q98936 | 1422 | PTPRG_CHICK Receptor-type tyrosine-protein ph... | 72 | 0.000002 | 56.6 | 40 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 57 | Q99952 | 460 | PTN18_HUMAN Tyrosine-protein phosphatase non-... | 271 | 1e-23 | 109 | 28 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 58 | P29074 | 926 | PTN4_HUMAN Tyrosine-protein phosphatase non-r... | 284 | 1e-23 | 112 | 27 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 59 | P28827 | 1452 | PTPRM_HUMAN Receptor-type tyrosine-protein ph... | 34 | 0.6 | 38.5 | 38 | 74 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB. | 60 | P35235 | 597 | PTN11_MOUSE Tyrosine-protein phosphatase non-... | 277 | 2e-23 | 110 | 29 | 40 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0051428; F:peptide hormone receptor binding; IPI:MGI.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0000077; P:DNA damage checkpoint; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0042445; P:hormone metabolic process; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0048609; P:multicellular organismal reproductive process; IMP:MGI.::GO:0051463; P:negative regulation of cortisol secretion; IMP:MGI.::GO:0060125; P:negative regulation of growth hormone secretion; IMP:MGI.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0046887; P:positive regulation of hormone secretion; IMP:MGI.::GO:0009967; P:positive regulation of signal transduction; IMP:MGI.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0046825; P:regulation of protein export from nucleus; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI. | 61 | P41499 | 597 | PTN11_RAT Tyrosine-protein phosphatase non-re... | 277 | 2e-23 | 110 | 29 | 40 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0043274; F:phospholipase binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB. |
